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Published in: Journal of the International AIDS Society 4/2010

Open Access 01-12-2010 | Poster presentation

Switch to once or twice daily unboosted atazanavir in a cohort of stable HIV patients: strong differences in drug exposure and virological outcome

Authors: T Baudry, A Boibieux, MC Gagnieu, L Cotte, JM Livrozet, P Miahles, D Makhloufi, C Chidiac, D Peyramond, T Ferry

Published in: Journal of the International AIDS Society | Special Issue 4/2010

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Excerpt

Switch to once daily unboosted (u) atazanavir (ATV) is an attractive option for HIV-infected patients with undetectable viral load, due to its convenience and favorable metabolic profile. However, due to a large interindividual variability, increased risk of inadequate ATV plasma concentrations (ATVc) and virological failure (VF) may be observed. Dividing the daily dose in a twice a day (BID) regimen could increase ATVc and improve virological success. …
Metadata
Title
Switch to once or twice daily unboosted atazanavir in a cohort of stable HIV patients: strong differences in drug exposure and virological outcome
Authors
T Baudry
A Boibieux
MC Gagnieu
L Cotte
JM Livrozet
P Miahles
D Makhloufi
C Chidiac
D Peyramond
T Ferry
Publication date
01-12-2010
Publisher
BioMed Central
DOI
https://doi.org/10.1186/1758-2652-13-S4-P47

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