Published in:
Open Access
01-12-2010 | Poster presentation
Short-course intensification with enfuvirtide in virologic failure: impact on intracellular HIV reservoir and on viral tropism (INNOVE study)
Authors:
J Ghosn, C Delaugerre, A Pinta, N Pierre, D Etienne, F Raffi, L Morand-Joubert
Published in:
Journal of the International AIDS Society
|
Special Issue 4/2010
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Excerpt
Overall, studies of ART intensification in suppressed patients showed no reduction in HIV reservoir, as assessed by proviral DNA. Limited data about impact of ART intensification are available for failing patients harbouring multidrug resistant viruses. We studied the effects of intensification with enfuvirtide (ENF) on intracellular HIV reservoir and tropism evolution under treatment selective pressure in this clinical setting. …