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Journal of the International AIDS Society

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Open Access 01-12-2010 | Poster presentation

Feasibility and effectiveness of combination antiretroviral therapy in HIV-infected infants in Pietermaritzburg, South Africa

Authors: D Van der Linden, S Purchase, NH McKerrow

Published in: Journal of the International AIDS Society | Special Issue 4/2010

Excerpt

In the absence of treatment, 50% of HIV-infected children will die before 2 years of age. In a recent randomized controlled trial, a 76% decrease in mortality was observed in infants receiving early combination antiretroviral therapy [1]. The World Health Organization now recommends starting all HIV-infected infants on combination antiretroviral therapy on diagnosis [2]. However, few data are available outside a well-controlled research setting. …

Violari A, Cotton MF, Gibb DM, Babike AG, Steyn J, Madhi SA, Jean-Philippe P, McIntyre JA: CHER Study Team. Early antiretroviral therapy and mortality among HIV-infected infants. N Engl J Med. 2008, 359 (21): 2233-44. 10.1056/NEJMoa0800971. Nov 20PubMedCentralCrossRefPubMed

World Health Organization: WHO antiretroviral therapy for infants and children. 2010, April 10, Last accessed 29 July 2010., [http://www.who.int/hiv/pub/paediatric/art_meeting_april2008/en/index.html]

Title: Feasibility and effectiveness of combination antiretroviral therapy in HIV-infected infants in Pietermaritzburg, South Africa
Authors: D Van der Linden
S Purchase
NH McKerrow
Publication date: 01-12-2010
Publisher: BioMed Central
Published in: Journal of the International AIDS Society / Issue Special Issue 4/2010
Electronic ISSN: 1758-2652
DOI: https://doi.org/10.1186/1758-2652-13-S4-P154

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