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Journal of the International AIDS Society
Published in: Journal of the International AIDS Society 4/2010

Open Access 01-12-2010 | Oral presentation

How early to start: what do observational data suggest?

Author: J Sterne

Published in: Journal of the International AIDS Society | Special Issue 4/2010

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Excerpt

National and international guidelines on antiretroviral therapy for HIV infection recently changed to recommend earlier treatment, following the publication during 2009 of two collaborative analyses of HIV cohort studies [1, 2]. These studies used different methodologies, and reached different conclusions about the benefits of very early treatment. I will describe their methods, and possible reasons for differences in their results. …
Literature
1.
Kitahata MM, Gange SJ, Abraham AG, NAACCORD Investigators, et al: Effect of early versus deferred antiretroviral therapy for HIV on survival. N Engl J Med. 2009, 360 (18): 1815-1826. 10.1056/NEJMoa0807252.PubMedCentralCrossRefPubMed
2.
When To Start Consortium: Timing of initiation of antiretroviral therapy in AIDS-free HIV-1-infected patients: a collaborative analysis of 18 HIV cohort studies. Lancet. 2009, 373 (9672): 1352-1363. 10.1016/S0140-6736(09)60612-7.PubMedCentralCrossRef
Metadata
Title
How early to start: what do observational data suggest?
Author
J Sterne
Publication date
01-12-2010
Publisher
BioMed Central
DOI
https://doi.org/10.1186/1758-2652-13-S4-O34

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