Published in:
Open Access
01-12-2010 | Oral presentation
Measurements of total and integrated HIV DNA demonstrate sporadic blips of unintegrated HIV DNA in HIV-positive patients on HAART
Authors:
A Mexas, E Graf, L Agosto, JJ Yu, M Pace, M Liszewski, S Migueles, M Connors, U O’Doherty
Published in:
Journal of the International AIDS Society
|
Special Issue 3/2010
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Excerpt
How HIV reservoirs are maintained on HAART remains unclear. Ongoing replication may contribute to reservoir maintenance and may occur at a low level that is not easy to detect. In the absence of ongoing replication, unintegrated HIV DNA should be lost over time; thus, monitoring total and integrated DNA may address this question. …