Published in:
Open Access
01-12-2012 | Review
Initial Emergency Department Diagnosis and Management of Adult Patients with Severe Sepsis and Septic Shock
Authors:
Sarah M Perman, Munish Goyal, David F Gaieski
Published in:
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
|
Issue 1/2012
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Abstract
Severe sepsis is a medical emergency affecting up to 18 million individuals world wide, with an annual incidence of 750,000 in North America alone. Mortality ranges between 28-50% of those individuals stricken by severe sepsis. Sepsis is a time critical illness, requiring early identification and prompt intervention in order to improve outcomes. This observation has led to increased awareness and education in the field of Emergency Medicine; it has also led to the implementation of critical interventions early in the course of patient management, specifically Early-Goal Directed Therapy, and rapid administration of appropriate antimicrobials. This review begins with a brief summary of the pathophysiology of sepsis, and then addresses the fundamental clinical aspects of ED identification and resuscitation of the septic patient.