Published in:
Open Access
01-12-2014 | Case report
Aminaphtone therapy in patients with type 1 diabetes and albuminuria: a case report
Authors:
Concetta Romano, Consuelo Tamburella, Martino Costa, Marco Messina, Anna Lisa Fassari, Marco Bertini
Published in:
Journal of Medical Case Reports
|
Issue 1/2014
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Abstract
Introduction
Microalbuminuria in type 1 diabetes is the earliest manifestation of diabetic microangiopathy (nephropathy). To date, the pharmacological approach to microangiopathy has not been shown to be useful. By using aminaphtone to control nephrologic complications of insulin-dependent diabetes mellitus we first obtained a significant improvement in microalbuminuria confirming this new pharmacological approach for insulin-dependent diabetes mellitus organospecific complications control.
Case presentation
After being treated with standard therapy for insulin-dependent diabetes mellitus (insulin) for more than 20 years, a 49-year-old white man affected by insulin-dependent diabetes mellitus adopted the standard therapy aminaphtone for a period of 2 months.
This therapy allowed a significant reduction of proteinuria from baseline evaluation that immediately increased after he stopped aminaphtone therapy.
Conclusions
Aminaphtone therapy, used globally in the treatment and prevention of endothelial dysfunctions, could be an interesting option for patients with insulin-dependent diabetes mellitus with the express purpose of preventing diabetic nephropathy.