Skip to main content
Top
Published in: Journal of Medical Case Reports 1/2014

Open Access 01-12-2014 | Case report

Diabetic neuropathic cachexia: a case report

Authors: Deeb D Naccache, William B Nseir, Moshe Z Herskovitz, Mogher H Khamaisi

Published in: Journal of Medical Case Reports | Issue 1/2014

Login to get access

Abstract

Introduction

We report a case of the rare entity of diabetic neuropathic cachexia, in order to remind clinicians that these cases still exist.

Case presentation

A 71-year-old Moslem Arab man with type 2 diabetes along with diabetic neuropathic cachexia complicated by a hyperfunctioning autonomous thyroid nodule, and undiagnosed acromegaly came under our care. We report the unique challenges as to what are the priorities to consider in the course of investigation and treatment. This case emphasizes the fast recovery from this remediable disorder, with antineuropathic medication and exogenous insulin to serve as an anabolic hormone on top of its hypoglycemic effect. Shared pathophysiologic aspects of diabetic neuropathic cachexia, cancerous etiologies and acute phase response are discussed.

Conclusions

Diabetic neuropathic cachexia is an integral differential diagnosis, whenever an intense neuropathic pain dominates patient complaints, accompanied with anorexia, weight loss as well as mood and sleep disturbances. This is an original case report of interest to internists, endocrinologists, diabetologists and pain clinic practitioners. Raising the suspicion of diabetic neuropathic cachexia early and concomitant to weight loss investigation, might curtail suffering and prompt early recovery from a severe illness that has a good prognosis.
Appendix
Available only for authorised users
Literature
2.
go back to reference Casi Casanellas A, del Cazo Cativiela FJ, Lanzón la Cruz C, Ortoll Batlle P: Early diagnosis of a case of diabetic neuropathic cachexia. Med Clin (Barc). 1986, 86: 865- Casi Casanellas A, del Cazo Cativiela FJ, Lanzón la Cruz C, Ortoll Batlle P: Early diagnosis of a case of diabetic neuropathic cachexia. Med Clin (Barc). 1986, 86: 865-
3.
go back to reference Chandler PT, Singh RS, Schwetschenau RP: Diabetic neuropathic cachexia. Acta Diabetologia Latina. 1978, 15: 212-216. 10.1007/BF02581067.CrossRef Chandler PT, Singh RS, Schwetschenau RP: Diabetic neuropathic cachexia. Acta Diabetologia Latina. 1978, 15: 212-216. 10.1007/BF02581067.CrossRef
4.
go back to reference Grewal J, Bril V, Lewis GF, Perkins BA: Objective evidence for the reversibility of nerve injury in diabetic neuropathic cachexia. Diabetes Care. 2006, 29: 473-474. 10.2337/diacare.29.02.06.dc05-2177.CrossRefPubMed Grewal J, Bril V, Lewis GF, Perkins BA: Objective evidence for the reversibility of nerve injury in diabetic neuropathic cachexia. Diabetes Care. 2006, 29: 473-474. 10.2337/diacare.29.02.06.dc05-2177.CrossRefPubMed
5.
go back to reference Puigdevall Gallego V, Rodríguez Ramírez J, Peña Quintana P, Gómez Díaz J: [Diabetic neuropathic cachexia: report of 2 cases]. Rev Clin Esp. 1988, 183: 504-505.PubMed Puigdevall Gallego V, Rodríguez Ramírez J, Peña Quintana P, Gómez Díaz J: [Diabetic neuropathic cachexia: report of 2 cases]. Rev Clin Esp. 1988, 183: 504-505.PubMed
6.
go back to reference Yuen KC, Day JL, Flannagan DW, Rayman G: Diabetic neuropathic cachexia and acute bilateral cataract formation following rapid glycaemic control in a newly diagnosed type 1 diabetic patient. Diabet Med. 2001, 18: 854-857. 10.1046/j.1464-5491.2001.00586.x.CrossRefPubMed Yuen KC, Day JL, Flannagan DW, Rayman G: Diabetic neuropathic cachexia and acute bilateral cataract formation following rapid glycaemic control in a newly diagnosed type 1 diabetic patient. Diabet Med. 2001, 18: 854-857. 10.1046/j.1464-5491.2001.00586.x.CrossRefPubMed
7.
go back to reference Al-Hajeri T, El-Gebely S, Abdella N: Profound weight loss in a type 2 diabetic patient with diabetic neuropathic cachexia: a case report. Diabetes Metab. 2009, 35: 422-424. 10.1016/j.diabet.2009.06.001.CrossRefPubMed Al-Hajeri T, El-Gebely S, Abdella N: Profound weight loss in a type 2 diabetic patient with diabetic neuropathic cachexia: a case report. Diabetes Metab. 2009, 35: 422-424. 10.1016/j.diabet.2009.06.001.CrossRefPubMed
8.
go back to reference Sheeran P, Hall GM: Cytokines in anaesthesia. Br J Anaesth. 1997, 78: 201-219. 10.1093/bja/78.2.201.CrossRefPubMed Sheeran P, Hall GM: Cytokines in anaesthesia. Br J Anaesth. 1997, 78: 201-219. 10.1093/bja/78.2.201.CrossRefPubMed
9.
go back to reference Desborough JP: The stress response to trauma and surgery. Br J Anaesth. 2000, 85: 109-117. 10.1093/bja/85.1.109.CrossRefPubMed Desborough JP: The stress response to trauma and surgery. Br J Anaesth. 2000, 85: 109-117. 10.1093/bja/85.1.109.CrossRefPubMed
Metadata
Title
Diabetic neuropathic cachexia: a case report
Authors
Deeb D Naccache
William B Nseir
Moshe Z Herskovitz
Mogher H Khamaisi
Publication date
01-12-2014
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2014
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-8-20

Other articles of this Issue 1/2014

Journal of Medical Case Reports 1/2014 Go to the issue