Skip to main content
Top
Published in: Journal of Medical Case Reports 1/2012

Open Access 01-12-2012 | Case report

Monophasic synovial sarcoma presenting as a primary ileal mass: a case report and review of the literature

Authors: Alaa N Alsharief, Musa Fageeh, Yousof Alabdulkarim

Published in: Journal of Medical Case Reports | Issue 1/2012

Login to get access

Abstract

Introduction

Synovial sarcoma is a rare malignant mesenchymal tumor mainly arising in the peri-articular tissue in young adults. There are few cases reported in other areas.

Case presentation

We report the case of a 29-year-old Saudi woman of Arabian ethnicity with synovial sarcoma arising primarily from the ileum who presented with abdominal pain, a palpable mass and incomplete intestinal obstruction. A literature review was performed to gather information on this rare gastrointestinal tract sarcoma.

Conclusions

Although it is a rare tumor of the pre-articular tissues, synovial sarcoma can present, in exceedingly rare cases, in unusual anatomical sites such as the gastrointestinal tract. We believe the reporting of all rare or unexpected presentations of sarcoma will eventually improve our understanding of this relatively unusual malignancy.
Appendix
Available only for authorised users
Literature
1.
go back to reference Billings SD, Meisner LF, Cummings OW, Tejada E: Synovial sarcoma of the upper digestive tract: a report of two cases with demonstration of the X;18 translocation by flouresence in situ hybridization. Mod Pathol. 2000, 13: 68-76. 10.1038/modpathol.3880011.CrossRefPubMed Billings SD, Meisner LF, Cummings OW, Tejada E: Synovial sarcoma of the upper digestive tract: a report of two cases with demonstration of the X;18 translocation by flouresence in situ hybridization. Mod Pathol. 2000, 13: 68-76. 10.1038/modpathol.3880011.CrossRefPubMed
2.
go back to reference Kumar V, Cotran RD, Robbins SL: Robbins Basic Pathology. 2007, Philadelphia, PA: Saunders, 8 Kumar V, Cotran RD, Robbins SL: Robbins Basic Pathology. 2007, Philadelphia, PA: Saunders, 8
3.
go back to reference Sphillane AJ, A'Hern R, Judson IR, Fisher C, Thomas JM: Synovial sarcoma: a clinicopathologica, staging, and prognostic assessment. J Clin Oncol. 2000, 18: 3794-3803. Sphillane AJ, A'Hern R, Judson IR, Fisher C, Thomas JM: Synovial sarcoma: a clinicopathologica, staging, and prognostic assessment. J Clin Oncol. 2000, 18: 3794-3803.
4.
go back to reference Park JK, Ham SY, Hwang JC, Jeong YK, Lee JH, Yang S, Suh J, Choi DH: Synovial sarcoma of the head and neck: a case of predominantly cystic mass. AJNR Am J Neuroradiol. 2004, 25: 1103-1105.PubMed Park JK, Ham SY, Hwang JC, Jeong YK, Lee JH, Yang S, Suh J, Choi DH: Synovial sarcoma of the head and neck: a case of predominantly cystic mass. AJNR Am J Neuroradiol. 2004, 25: 1103-1105.PubMed
5.
go back to reference Pai S, Chinoy RF, Pradhan SA, D'Cruz AK, Kane SV, Yadav JN: Head and neck synovial sarcinomas. J Surg Oncol. 1993, 54: 82-86. 10.1002/jso.2930540206.CrossRefPubMed Pai S, Chinoy RF, Pradhan SA, D'Cruz AK, Kane SV, Yadav JN: Head and neck synovial sarcinomas. J Surg Oncol. 1993, 54: 82-86. 10.1002/jso.2930540206.CrossRefPubMed
6.
go back to reference Zamarron C, Abdulkader I, Alvarez UC, Baron FJ, Prim JM, Ledo RL, Forteza J: Primary synovial sarcoma of the lung. Intern Med. 2006, 45: 679-683. 10.2169/internalmedicine.45.1508.CrossRefPubMed Zamarron C, Abdulkader I, Alvarez UC, Baron FJ, Prim JM, Ledo RL, Forteza J: Primary synovial sarcoma of the lung. Intern Med. 2006, 45: 679-683. 10.2169/internalmedicine.45.1508.CrossRefPubMed
7.
go back to reference Etienne-Mastroianni B, Falchero L, Chalabrevesse L, Loire R, Ranchere D, Souguet PJ, Cordier JF: Primary sarcomas of the lung: a clinicopathologic study of 12 cases. Lung Cancer. 2002, 38: 283-289. 10.1016/S0169-5002(02)00303-3.CrossRefPubMed Etienne-Mastroianni B, Falchero L, Chalabrevesse L, Loire R, Ranchere D, Souguet PJ, Cordier JF: Primary sarcomas of the lung: a clinicopathologic study of 12 cases. Lung Cancer. 2002, 38: 283-289. 10.1016/S0169-5002(02)00303-3.CrossRefPubMed
8.
go back to reference Mermigkis CM, Kopanakis A, Patentalakis G, Polychronopoulos V, Patentalakis M: Primary monophasic synovial sarcoma presenting as a pulmonary mass: a case report. J Med Case Reports. 2008, 2: 18-10.1186/1752-1947-2-18.CrossRefPubMedCentral Mermigkis CM, Kopanakis A, Patentalakis G, Polychronopoulos V, Patentalakis M: Primary monophasic synovial sarcoma presenting as a pulmonary mass: a case report. J Med Case Reports. 2008, 2: 18-10.1186/1752-1947-2-18.CrossRefPubMedCentral
9.
go back to reference Nicholson AG, Rigby M, Lincoln C, Meller S, Fisher C: Synovial sarcoma of the heart. Histopathology. 1997, 30: 349-352. 10.1046/j.1365-2559.1997.d01-616.x.CrossRefPubMed Nicholson AG, Rigby M, Lincoln C, Meller S, Fisher C: Synovial sarcoma of the heart. Histopathology. 1997, 30: 349-352. 10.1046/j.1365-2559.1997.d01-616.x.CrossRefPubMed
10.
go back to reference Shmookler BM: Retroperitoneal synovial sarcoma. A report of four cases. Am J Clin Pathol. 1982, 77: 686-691.CrossRefPubMed Shmookler BM: Retroperitoneal synovial sarcoma. A report of four cases. Am J Clin Pathol. 1982, 77: 686-691.CrossRefPubMed
11.
go back to reference Jun L, Ke S, Zhaoming W, Linjie X, Xinru Y: Primary synovial sarcoma of the prostate: report of 2 cases and literature review. Int J Surg Pathol. 2008, 16: 329-334. 10.1177/1066896907309575.CrossRefPubMed Jun L, Ke S, Zhaoming W, Linjie X, Xinru Y: Primary synovial sarcoma of the prostate: report of 2 cases and literature review. Int J Surg Pathol. 2008, 16: 329-334. 10.1177/1066896907309575.CrossRefPubMed
12.
go back to reference Chu PG, Benhattar J, Weiss LM, Meagher-Villemure K: Intraneural synovial sarcoma: two cases. Mod Pathol. 2004, 17: 258-263. 10.1038/modpathol.3800048.CrossRefPubMed Chu PG, Benhattar J, Weiss LM, Meagher-Villemure K: Intraneural synovial sarcoma: two cases. Mod Pathol. 2004, 17: 258-263. 10.1038/modpathol.3800048.CrossRefPubMed
13.
go back to reference Medina-Franco H, Ramos-De la Medina A, Cortes-Gonzalez R, Baquera J, Angeles-Angeles A, Urist MM, Eltoum IE, Heslin MJ: Expression of p53 and proliferation index as prognostic factors in gastrointestinal sarcomas. Ann Surg Oncol. 2003, 10: 190-195. 10.1245/ASO.2003.03.033.CrossRefPubMed Medina-Franco H, Ramos-De la Medina A, Cortes-Gonzalez R, Baquera J, Angeles-Angeles A, Urist MM, Eltoum IE, Heslin MJ: Expression of p53 and proliferation index as prognostic factors in gastrointestinal sarcomas. Ann Surg Oncol. 2003, 10: 190-195. 10.1245/ASO.2003.03.033.CrossRefPubMed
14.
go back to reference Medina-Franco H, Eltoum IE, Urist MM, Heslin MJ: Primary gastrointestinal sarcomas. Am Surg. 2000, 66: 1-5. Medina-Franco H, Eltoum IE, Urist MM, Heslin MJ: Primary gastrointestinal sarcomas. Am Surg. 2000, 66: 1-5.
15.
go back to reference Miettinen M, Lasota J: Gastrointestinal stromal tumors - definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis. Virchows Arch. 2001, 438: 1-12. 10.1007/s004280000338.CrossRefPubMed Miettinen M, Lasota J: Gastrointestinal stromal tumors - definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis. Virchows Arch. 2001, 438: 1-12. 10.1007/s004280000338.CrossRefPubMed
16.
go back to reference Palmer BV, Levene A, Shaw H: Synovial sarcoma of the pharynx and oesophagus. J Laryngol Otol. 1983, 97: 1173-1176.CrossRefPubMed Palmer BV, Levene A, Shaw H: Synovial sarcoma of the pharynx and oesophagus. J Laryngol Otol. 1983, 97: 1173-1176.CrossRefPubMed
17.
go back to reference Amr SS, Shihabi NK, AI Hajj H: Synovial sarcoma of the esophagus. Am J Otolaryngol. 1984, 5: 266-269. 10.1016/S0196-0709(84)80037-X.CrossRefPubMed Amr SS, Shihabi NK, AI Hajj H: Synovial sarcoma of the esophagus. Am J Otolaryngol. 1984, 5: 266-269. 10.1016/S0196-0709(84)80037-X.CrossRefPubMed
18.
go back to reference Bloch MJ, lozzo RV, Edmunds H, Brooks JJ: Polypoid synovial sarcoma of the esophagus. Gastroenterology. 1987, 92: 229-233.CrossRefPubMed Bloch MJ, lozzo RV, Edmunds H, Brooks JJ: Polypoid synovial sarcoma of the esophagus. Gastroenterology. 1987, 92: 229-233.CrossRefPubMed
19.
go back to reference Pulpeiro JR, Cruz R, Arenas A, Perez-Espejo G: Para-oesophageal synovial sarcoma. Eur J Radiol. 1988, 18: 120-121. Pulpeiro JR, Cruz R, Arenas A, Perez-Espejo G: Para-oesophageal synovial sarcoma. Eur J Radiol. 1988, 18: 120-121.
20.
go back to reference Caldwell CB, Bains MS, Burt M: Unusual malignant neoplasm of the esophagus. Oat cell carcinoma, melanoma, and sarcoma. J Thorac Cardiovasc Surg. 1991, 101: 100-107.PubMed Caldwell CB, Bains MS, Burt M: Unusual malignant neoplasm of the esophagus. Oat cell carcinoma, melanoma, and sarcoma. J Thorac Cardiovasc Surg. 1991, 101: 100-107.PubMed
21.
go back to reference Perch SJ, Soffen EM, Whittington R, Brooks JJ: Esophageal sarcomas. J Surg Oncol. 1991, 48: 194-198. 10.1002/jso.2930480311.CrossRefPubMed Perch SJ, Soffen EM, Whittington R, Brooks JJ: Esophageal sarcomas. J Surg Oncol. 1991, 48: 194-198. 10.1002/jso.2930480311.CrossRefPubMed
22.
go back to reference Anton-Pacheco J, Cano I, Cuadros J, Vilarino A, Berchi F: Synovial sarcoma of the esophagus. J Pediatr Surg. 1996, 31: 1703-1705. 10.1016/S0022-3468(96)90057-3.CrossRefPubMed Anton-Pacheco J, Cano I, Cuadros J, Vilarino A, Berchi F: Synovial sarcoma of the esophagus. J Pediatr Surg. 1996, 31: 1703-1705. 10.1016/S0022-3468(96)90057-3.CrossRefPubMed
23.
go back to reference Habu S, Okamoto E, Toyosaka A, Takeuchi M: Synovial sarcoma of the esophagus: report of a case. Surg Today. 1998, 28: 401-404. 10.1007/s005950050149.CrossRefPubMed Habu S, Okamoto E, Toyosaka A, Takeuchi M: Synovial sarcoma of the esophagus: report of a case. Surg Today. 1998, 28: 401-404. 10.1007/s005950050149.CrossRefPubMed
24.
go back to reference Bonavina L, Fociani P, Asnaghi D, Ferrero S: Synovial sarcoma of the esophagus simulating achalasia. Dis Esophagus. 1998, 11: 268-271.PubMed Bonavina L, Fociani P, Asnaghi D, Ferrero S: Synovial sarcoma of the esophagus simulating achalasia. Dis Esophagus. 1998, 11: 268-271.PubMed
25.
go back to reference Billings SD, Meisner LF, Cummings OW, Tejada E: Synovial sarcoma of the upper digestive tract: a report of two cases with demonstration of the X;18 translocation by fluorescence in situ hybridization. Mod Pathol. 2000, 13: 68-76. 10.1038/modpathol.3880011.CrossRefPubMed Billings SD, Meisner LF, Cummings OW, Tejada E: Synovial sarcoma of the upper digestive tract: a report of two cases with demonstration of the X;18 translocation by fluorescence in situ hybridization. Mod Pathol. 2000, 13: 68-76. 10.1038/modpathol.3880011.CrossRefPubMed
26.
go back to reference Chan GS, Yuen ST, Chan KW: Synovial sarcoma presenting as a polypoid jejunal mass. Histopathology. 2004, 44: 191-193. 10.1111/j.1365-2559.2004.01780.x.CrossRefPubMed Chan GS, Yuen ST, Chan KW: Synovial sarcoma presenting as a polypoid jejunal mass. Histopathology. 2004, 44: 191-193. 10.1111/j.1365-2559.2004.01780.x.CrossRefPubMed
27.
go back to reference Butori C, Hofman V, Attias R, Mouroux J, Pedeutour F, Hofman P: Diagnosis of primary esophageal synovial sarcoma by demonstration of t(X;18) translocation: a case report. Virchows Arch. 2006, 449: 262-267. 10.1007/s00428-006-0234-1.CrossRefPubMed Butori C, Hofman V, Attias R, Mouroux J, Pedeutour F, Hofman P: Diagnosis of primary esophageal synovial sarcoma by demonstration of t(X;18) translocation: a case report. Virchows Arch. 2006, 449: 262-267. 10.1007/s00428-006-0234-1.CrossRefPubMed
28.
go back to reference Akhunji S, Musil I, Baisre de Leon A, Bhattacharyya A, Cranmer LD: Synovial sarcoma arising in the gastric wall: case report and literature review. Cancer Therapy. 2007, 5: 457-462. Akhunji S, Musil I, Baisre de Leon A, Bhattacharyya A, Cranmer LD: Synovial sarcoma arising in the gastric wall: case report and literature review. Cancer Therapy. 2007, 5: 457-462.
29.
go back to reference Parfitt JR, Xu J, Kontozoglou T, Oluwafemi AR, Driman DK: Primary monophasic synovial sarcoma of the colon. Histopathology. 2007, 50: 521-523. 10.1111/j.1365-2559.2007.02603.x.CrossRefPubMed Parfitt JR, Xu J, Kontozoglou T, Oluwafemi AR, Driman DK: Primary monophasic synovial sarcoma of the colon. Histopathology. 2007, 50: 521-523. 10.1111/j.1365-2559.2007.02603.x.CrossRefPubMed
30.
go back to reference Schreiber-Facklam H, Bode-Lesniewska B, Frigerio S, Flury R: Primary monophasic synovial sarcoma of the duodenum with SYT/SSX2 type of translocation. Hum Pathol. 2007, 38: 946-949. 10.1016/j.humpath.2007.01.018.CrossRefPubMed Schreiber-Facklam H, Bode-Lesniewska B, Frigerio S, Flury R: Primary monophasic synovial sarcoma of the duodenum with SYT/SSX2 type of translocation. Hum Pathol. 2007, 38: 946-949. 10.1016/j.humpath.2007.01.018.CrossRefPubMed
31.
go back to reference Company-Campins MM, Morales R, Dolz C, Garcia-Bonate M, Vilella A, Huguet P: Primary monophasic synovial sarcoma of the duodenum confirmed by cytogenetic analysis with demonstration of t(X;18): a case report. J Gastrointestin Liver Dis. 2009, 18: 89-93.PubMed Company-Campins MM, Morales R, Dolz C, Garcia-Bonate M, Vilella A, Huguet P: Primary monophasic synovial sarcoma of the duodenum confirmed by cytogenetic analysis with demonstration of t(X;18): a case report. J Gastrointestin Liver Dis. 2009, 18: 89-93.PubMed
32.
go back to reference Makhlouf HR, Ahrens W, Agarwal B, Dow N, Marshalleck JJ, Lee EL, Dotto JE, Hui P, Sobin LH, Oliveira A, Miettinen M: Synovial sarcoma of the stomach: a clinicopathologic, immunohistochemical, and molecular genetic study of 10 cases. Am J Surg Pathol. 2008, 32: 275-281. 10.1097/PAS.0b013e31812e6a58.CrossRefPubMed Makhlouf HR, Ahrens W, Agarwal B, Dow N, Marshalleck JJ, Lee EL, Dotto JE, Hui P, Sobin LH, Oliveira A, Miettinen M: Synovial sarcoma of the stomach: a clinicopathologic, immunohistochemical, and molecular genetic study of 10 cases. Am J Surg Pathol. 2008, 32: 275-281. 10.1097/PAS.0b013e31812e6a58.CrossRefPubMed
33.
go back to reference Bergh P, Meis-Kindblom JM, Gherlinzoni F, Berlin O Bacchini P, Bertoni F, Gunterberg B, Kindblom LG: Synovial sarcoma: identification of low and high risk groups. Cancer. 1999, 85: 2596-2607. 10.1002/(SICI)1097-0142(19990615)85:12<2596::AID-CNCR16>3.0.CO;2-K.CrossRefPubMed Bergh P, Meis-Kindblom JM, Gherlinzoni F, Berlin O Bacchini P, Bertoni F, Gunterberg B, Kindblom LG: Synovial sarcoma: identification of low and high risk groups. Cancer. 1999, 85: 2596-2607. 10.1002/(SICI)1097-0142(19990615)85:12<2596::AID-CNCR16>3.0.CO;2-K.CrossRefPubMed
Metadata
Title
Monophasic synovial sarcoma presenting as a primary ileal mass: a case report and review of the literature
Authors
Alaa N Alsharief
Musa Fageeh
Yousof Alabdulkarim
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2012
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-6-83

Other articles of this Issue 1/2012

Journal of Medical Case Reports 1/2012 Go to the issue