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Virchows Archiv
Published in: Virchows Archiv 2/2006

01-08-2006 | Case Report

Diagnosis of primary esophageal synovial sarcoma by demonstration of t(X;18) translocation: a case report

Authors: Catherine Butori, Véronique Hofman, Rita Attias, Jerôme Mouroux, Florence Pedeutour, Paul Hofman

Published in: Virchows Archiv | Issue 2/2006

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Abstract

Synovial sarcoma (SS) is an uncommon soft tissue tumor occurring mainly in the periarticular region of the extremities of young adults. In this report, we describe a very rare occurrence of primary SS of the esophagus in a 72-year-old woman. Histologically, the tumor demonstrated biphasic morphologic findings associated with poorly differentiated areas. Tumor cells expressed vimentin, epithelial (EMA, CK7, AE1/3), bcl-2 and neuroectodermal (CD56, CD57, CD99) antigens. Differential diagnose included esophageal sarcomatoid carcinoma. Cytogenetic analysis confirmed the diagnosis of SS by identifying t(X;18) translocation. The literature of this very uncommon entity of the esophagus is reviewed.
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Metadata
Title
Diagnosis of primary esophageal synovial sarcoma by demonstration of t(X;18) translocation: a case report
Authors
Catherine Butori
Véronique Hofman
Rita Attias
Jerôme Mouroux
Florence Pedeutour
Paul Hofman
Publication date
01-08-2006
Publisher
Springer-Verlag
Published in
Virchows Archiv / Issue 2/2006
Print ISSN: 0945-6317
Electronic ISSN: 1432-2307
DOI
https://doi.org/10.1007/s00428-006-0234-1

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