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Published in: Journal of Medical Case Reports 1/2012

Open Access 01-12-2012 | Case report

Homonymous Quadrantanopsia as the First Manifestation of Cerebral Metastasis of Invasive Mole: a case report

Authors: De-Lu Song, Yong Zhong, Feng Feng, Yuan Li, Meng-Hui Li

Published in: Journal of Medical Case Reports | Issue 1/2012

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Abstract

Introduction

Homonymous quadrantanopsia results from retrochiasmal lesions in the visual pathway. Invasive mole is a benign tumor that arises from myometrial invasion of a hydatidiform mole via direct extension through tissue or venous channels. Cerebral metastasis of invasive mole is rare and there has been no report demonstrating homonymous quadrantanopsia as the first manifestation of metastasis in any trophoblastic neoplasms.

Case presentation

We report the case of a 31-year-old Asian woman who presented with right homonymous inferior quadrantanopsia from the mass effect of a solitary cerebral metastasis from an invasive mole. A magnetic resonance image (MRI) of the brain showed a metastatic tumor in the left occipital lobe. The visual field improved slightly after chemotherapy. There was a reduction in the tumor size and the surrounding edema. This is the first case report demonstrating that homonymous quadrantanopsia should be included in the manifestations of the metastasis of an invasive mole.

Conclusions

The presentation of homonymous quadrantanopsia must alert ophthalmologists to conduct a complete medical history and arrange specialist consultation.
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Literature
1.
go back to reference Zhang X, Kedar S, Lynn MJ, Newman NJ, Biousse V: Homonymous hemianopias: clinical-anatomic correlations in 904 cases. Neurology. 2006, 66: 906-910. 10.1212/01.wnl.0000203913.12088.93.CrossRefPubMed Zhang X, Kedar S, Lynn MJ, Newman NJ, Biousse V: Homonymous hemianopias: clinical-anatomic correlations in 904 cases. Neurology. 2006, 66: 906-910. 10.1212/01.wnl.0000203913.12088.93.CrossRefPubMed
2.
go back to reference Lurain JR, Brewer JI: Invasive mole. Semin Oncol. 1982, 9: 174-180.PubMed Lurain JR, Brewer JI: Invasive mole. Semin Oncol. 1982, 9: 174-180.PubMed
3.
go back to reference Lurain JR: Gestational trophoblastic disease I: epidemiology, pathology, clinical presentation and diagnosis of gestational trophoblastic disease, and management of hydatidiform mole. Am J Obstet Gynecol. 2010, 203: 531-539. 10.1016/j.ajog.2010.06.073.CrossRefPubMed Lurain JR: Gestational trophoblastic disease I: epidemiology, pathology, clinical presentation and diagnosis of gestational trophoblastic disease, and management of hydatidiform mole. Am J Obstet Gynecol. 2010, 203: 531-539. 10.1016/j.ajog.2010.06.073.CrossRefPubMed
4.
go back to reference Evans AC, Soper JT, Clarke-Pearson DL, Berchuck A, Rodriguez GC, Hammond CB: Gestational trophoblastic disease metastatic to the central nervous system. Gynecol Oncol. 1995, 59: 226-230. 10.1006/gyno.1995.0013.CrossRefPubMed Evans AC, Soper JT, Clarke-Pearson DL, Berchuck A, Rodriguez GC, Hammond CB: Gestational trophoblastic disease metastatic to the central nervous system. Gynecol Oncol. 1995, 59: 226-230. 10.1006/gyno.1995.0013.CrossRefPubMed
5.
go back to reference Newlands ES, Holden L, Seckl MJ, McNeish I, Strickland S, Rustin GJ: Management of brain metastases in patients with high-risk gestational trophoblastic tumors. J Reprod Med. 2002, 47: 465-471.PubMed Newlands ES, Holden L, Seckl MJ, McNeish I, Strickland S, Rustin GJ: Management of brain metastases in patients with high-risk gestational trophoblastic tumors. J Reprod Med. 2002, 47: 465-471.PubMed
6.
go back to reference Rampini P, Alimehmeti R, Egidi M, Locatelli M, Zavanone M: Left quadrantanopsia caused by traumatic subclavian steal syndrome. J Trauma. 2004, 56: 1342-1344. 10.1097/01.TA.0000052367.00866.5E.CrossRefPubMed Rampini P, Alimehmeti R, Egidi M, Locatelli M, Zavanone M: Left quadrantanopsia caused by traumatic subclavian steal syndrome. J Trauma. 2004, 56: 1342-1344. 10.1097/01.TA.0000052367.00866.5E.CrossRefPubMed
7.
go back to reference Donzis PB, Factor JS: Visual field loss resulting from cervical chiropractic manipulation. Am J Ophthalmol. 1997, 123: 851-852.CrossRefPubMed Donzis PB, Factor JS: Visual field loss resulting from cervical chiropractic manipulation. Am J Ophthalmol. 1997, 123: 851-852.CrossRefPubMed
8.
go back to reference Gomez CR, Bhat MH, Chung HD: Homonymous quadrantic visual field defect resulting from vertebrobasilar insufficiency: report of a case. Angiology. 1990, 41: 151-155. 10.1177/000331979004100210.CrossRefPubMed Gomez CR, Bhat MH, Chung HD: Homonymous quadrantic visual field defect resulting from vertebrobasilar insufficiency: report of a case. Angiology. 1990, 41: 151-155. 10.1177/000331979004100210.CrossRefPubMed
9.
go back to reference Smith JL: Homonymous hemianopia. A review of one hundred cases. Am J Ophthalmol. 1962, 54: 616-623.CrossRefPubMed Smith JL: Homonymous hemianopia. A review of one hundred cases. Am J Ophthalmol. 1962, 54: 616-623.CrossRefPubMed
10.
go back to reference Groom M, Kay MD, Vicinanza-Adami C, Santini R: Optic tract syndrome secondary to metastatic breast cancer. Am J Ophthalmol. 1998, 125: 115-118. 10.1016/S0002-9394(99)80251-7.CrossRefPubMed Groom M, Kay MD, Vicinanza-Adami C, Santini R: Optic tract syndrome secondary to metastatic breast cancer. Am J Ophthalmol. 1998, 125: 115-118. 10.1016/S0002-9394(99)80251-7.CrossRefPubMed
11.
go back to reference Baehring JM, de Lotbiniere A, Bannykh S: Heteronymous inferior quadrantanopsia from a hypothalamic metastasis. J Neurooncol. 2005, 75: 345-346. 10.1007/s11060-005-4032-4.CrossRefPubMed Baehring JM, de Lotbiniere A, Bannykh S: Heteronymous inferior quadrantanopsia from a hypothalamic metastasis. J Neurooncol. 2005, 75: 345-346. 10.1007/s11060-005-4032-4.CrossRefPubMed
Metadata
Title
Homonymous Quadrantanopsia as the First Manifestation of Cerebral Metastasis of Invasive Mole: a case report
Authors
De-Lu Song
Yong Zhong
Feng Feng
Yuan Li
Meng-Hui Li
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2012
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-6-117

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