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Open Access 01-12-2011 | Case report

Neuroendocrine tumor presenting like lymphoma: a case report

Authors: Riccardo Del Vescovo, Roberto Luigi Cazzato, Sofia Battisti, Francesco D'Agostino, Bruno Vincenzi, Rosario Francesco Grasso, Bruno Beomonte Zobel

Published in: Journal of Medical Case Reports | Issue 1/2011

Abstract

Introduction

Neuroendocrine tumors are a rare but diverse group of malignancies that arise in a wide range of organ systems, including the mediastinum. Differential diagnosis includes other masses arising in the middle mediastinum such as lymphoma, pericardial, bronchogenic and enteric cysts, metastatic tumors, xanthogranuloma, systemic granuloma, diaphragmatic hernia, meningocele and paravertebral abscess.

Case presentation

We present a case of 42-year-old Caucasian man with a neuroendocrine tumor of the middle-posterior mediastinum and liver metastases, which resembled a lymphoma on magnetic resonance imaging.

Conclusion

The differential diagnosis in patients with mediastinal masses and liver lesions should include neuroendocrine tumor.

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Strollo DC, de Christenson MLR, Jett JR: Primary mediastinal tumours. Part II. Tumors of the middle and posterior mediastinum. Chest. 1997, 112 (5): 1344-1357. 10.1378/chest.112.5.1344.CrossRefPubMed

Duwe BV, Sterman DH, Musani AI: Tumors of the Mediastinum. Chest. 2005, 128 (4): 2893-2909. 10.1378/chest.128.4.2893.CrossRefPubMed

Crapo JD, Glassroth J, Karlinsky J, King TE: Baum's textbook of pulmonary diseases. 2004, Philadelphia, PA: Lippincott Williams & Wilkins, 883-912.

Macchiarini P, Ostertag H: Uncommon primary mediastinal tumours. Lancet Oncol. 2004, 5 (2): 107-118. 10.1016/S1470-2045(04)01385-3.CrossRefPubMed

Steward MJ, Warbey VS, Malhotra A, Caplin ME, Buscombe JR, Yu D: Neuroendocrine tumors: role of interventional radiology in therapy. Radiographics. 2008, 28 (4): 1131-1145. 10.1148/rg.284075170.CrossRefPubMed

Socia E, Kloppel G, Sobin LH: Histologic typing of endocrine tumors. WHO international histological classification of tumors. 2000, Heidelberg, Germany: Springer Verlag

Castellino RA, Blank N, Hoppe RT, Cho C: Hodgkin disease: contributions of chest CT in the initial staging evaluation. Radiology. 1986, 160 (3): 603-605.CrossRefPubMed

Castellino RA, Hilton S, O'Brien JP, Portlock CS: Non-Hodgkin lymphoma: contribution of chest CT in the initial staging evaluation. Radiology. 1996, 199 (1): 129-132.CrossRefPubMed

Sharma A, Fidias P, Hayman LA, Loomis SL, Taber KH, Aquino SL: Patterns of lymphadenopathy in thoracic malignancies. Radiographics. 2004, 24 (2): 419-434. 10.1148/rg.242035075.CrossRefPubMed

10.

Dromain C, de Baere T, Lumbroso J, Caillet H, Laplanche A, Boige V, Ducreux M, Duvillard P, Elias D, Schlumberger M, Sigal R, Baudin E: Detection of liver metastases from endocrine tumors: a prospective comparison of somatostatin receptor scintigraphy, computed tomography, and magnetic resonance imaging. J Clin Oncol. 2005, 23 (1): 70-78.CrossRefPubMed

11.

McStay MK, Maudgil D, Williams M, Tibballs JM, Watkinson AF, Caplin ME, Buscombe JR: Large volume liver metastases from neuroendocrine tumors: hepatic intraarterial 90Y-DOTA-lanreotide as effective palliative therapy. Radiology. 2005, 237 (2): 718-726. 10.1148/radiol.2372041203.CrossRefPubMed

12.

Gupta S, Johnson MM, Murthy R, Ahrar K, Wallace MJ, Madoff DC, McRae SE, Hicks ME, Rao S, Vauthey JN, Ajani JA, Yao JC: Hepatic arterial embolization and chemoembolization for the treatment of patients with metastatic neuroendocrine tumors: variables affecting response rates and survival. Cancer. 2005, 104 (8): 1590-1602. 10.1002/cncr.21389.CrossRefPubMed

13.

14.

Atwell TD, Charboneau JW, Que FG, Rubin J, Lewis BD, Nagorney DM, Callstrom MR, Farrell MA, Pitot HC, Hobday TJ: Treatment of neuroendocrine cancer metastatic to the liver: the role of ablative techniques. Cardiovasc Intervent Radiol. 2005, 28 (4): 409-421. 10.1007/s00270-004-4082-6.CrossRefPubMed

15.

Shetty PK, Baliga SV, Balaiah K, Bnana PS: Primary hepatic neuroendocrine tumor: an unusual cystic presentation. Indian J Path Microbiol. 2010, 53 (4): 760-762. 10.4103/0377-4929.72078.CrossRef

Title: Neuroendocrine tumor presenting like lymphoma: a case report
Authors: Riccardo Del Vescovo
Roberto Luigi Cazzato
Sofia Battisti
Francesco D'Agostino
Bruno Vincenzi
Rosario Francesco Grasso
Bruno Beomonte Zobel
Publication date: 01-12-2011
Publisher: BioMed Central
Published in: Journal of Medical Case Reports / Issue 1/2011
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/1752-1947-5-506

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Neuroendocrine tumor presenting like lymphoma: a case report

Abstract

Introduction

Case presentation

Conclusion

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Introduction

Case presentation

Conclusion

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