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Published in: Journal of Medical Case Reports 1/2011

Open Access 01-12-2011 | Case report

Giant condyloma acuminatum of the scrotum in a man with AIDS: a case report

Authors: Peter M Nthumba, Peter Ngure, Patrick Nyoro

Published in: Journal of Medical Case Reports | Issue 1/2011

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Abstract

Introduction

Giant condyloma acuminatum, also called a Buschke-Löwenstein tumor, first described in 1925, is a slow-growing, locally aggressive, destructive tumor of the ano-genital region. Scrotal tumors are rare. Reports on giant condyloma acuminatum lesions in patients with HIV and AIDS are surprisingly even rarer.

Case presentation

In this report, we present the case of a 42-year-old African man with AIDS who was undergoing anti-retroviral therapy. He was found to have a giant condyloma acuminatum of the scrotum. Wide surgical excision and scrotal reconstruction with a pedicled anterolateral thigh flap was performed, significantly improving his quality of life.

Conclusion

Decision making regarding the goals of surgical intervention in the terminally ill is a complex process. The options include conservative medical palliation or palliative excision versus a curative excision that has the potential for significant morbidity. Wide surgical excision with local flap reconstruction significantly improved the quality of life of the patient described herein. The challenges presented by emerging or unusual presentations of surgical pathology secondary to HIV and AIDS in patients who are on anti-retroviral therapy provide an opportunity for research and the establishment of guidelines for the use of adjuvant chemotherapy in these patients.
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Literature
1.
go back to reference Gholam P, Enk A, Hartschuh W: Successful surgical management of giant condyloma acuminatum (Buschke-Löwenstein tumor) in the genitoanal region: a case report and evaluation of current therapies. Dermatology. 2009, 218: 56-59. 10.1159/000165359.CrossRefPubMed Gholam P, Enk A, Hartschuh W: Successful surgical management of giant condyloma acuminatum (Buschke-Löwenstein tumor) in the genitoanal region: a case report and evaluation of current therapies. Dermatology. 2009, 218: 56-59. 10.1159/000165359.CrossRefPubMed
2.
go back to reference Bertram P, Treutner KH, Rübben A, Hauptmann S, Schumpelick V: Invasive squamous-cell carcinoma in giant anorectal condyloma (Buschke-Löwenstein tumor). Langenbecks Arch Chir. 1995, 380: 115-118.CrossRefPubMed Bertram P, Treutner KH, Rübben A, Hauptmann S, Schumpelick V: Invasive squamous-cell carcinoma in giant anorectal condyloma (Buschke-Löwenstein tumor). Langenbecks Arch Chir. 1995, 380: 115-118.CrossRefPubMed
3.
go back to reference Meli BG, Ramos H, Gomez LAD: Giant condyloma acuminatum (Buschke-Loewenstein tumour) of the scrotum. Eur J Plast Surg. 1994, 17: 43-47.CrossRef Meli BG, Ramos H, Gomez LAD: Giant condyloma acuminatum (Buschke-Loewenstein tumour) of the scrotum. Eur J Plast Surg. 1994, 17: 43-47.CrossRef
4.
go back to reference Sepou A, Zoguereh DD: [Giant anovulvar condyloma acuminata revealing HIV-1 seropositivity in a Centrafrican patient] [in French]. Med Trop (Mars). 1998, 58: 378-380. Sepou A, Zoguereh DD: [Giant anovulvar condyloma acuminata revealing HIV-1 seropositivity in a Centrafrican patient] [in French]. Med Trop (Mars). 1998, 58: 378-380.
5.
go back to reference Granados E, Palou J, Rios G, Vicente J: Urologic pathology in patients positive for anti-HIV antibodies. Actas Urol Esp. 1989, 13: 378-380.PubMed Granados E, Palou J, Rios G, Vicente J: Urologic pathology in patients positive for anti-HIV antibodies. Actas Urol Esp. 1989, 13: 378-380.PubMed
6.
go back to reference Garazzino S, Canavese F, Coppo P, Cortese MG, Pucci A, Mignone F, Tovo PA: An infant presenting with a voluminous exophytic perineal mass. Pediatr Infect Dis J. 2010, 29: 577-583. 10.1097/INF.0b013e3181cf428c.CrossRefPubMed Garazzino S, Canavese F, Coppo P, Cortese MG, Pucci A, Mignone F, Tovo PA: An infant presenting with a voluminous exophytic perineal mass. Pediatr Infect Dis J. 2010, 29: 577-583. 10.1097/INF.0b013e3181cf428c.CrossRefPubMed
7.
go back to reference Landin L, Rodriguez-Perez JC, Garcia-Bello MA, Cavadas PC, Thione A, Nthumba P, Blanes M, Ibañez J: Kidney transplants in HIV-positive recipients under HAART: a comprehensive review and meta-analysis of 12 series. Nephrol Dial Transplant. 2010, 9: 3106-3115.CrossRef Landin L, Rodriguez-Perez JC, Garcia-Bello MA, Cavadas PC, Thione A, Nthumba P, Blanes M, Ibañez J: Kidney transplants in HIV-positive recipients under HAART: a comprehensive review and meta-analysis of 12 series. Nephrol Dial Transplant. 2010, 9: 3106-3115.CrossRef
8.
go back to reference Tytherleigh MG, Birtle AJ, Cohen CE, Glynne-Jones R, Livingstone J, Gilbert J: Combined surgery and chemoradiation as a treatment for the Buschke-Löwenstein tumour. Surgeon. 2006, 4: 378-383. 10.1016/S1479-666X(06)80114-9.CrossRefPubMed Tytherleigh MG, Birtle AJ, Cohen CE, Glynne-Jones R, Livingstone J, Gilbert J: Combined surgery and chemoradiation as a treatment for the Buschke-Löwenstein tumour. Surgeon. 2006, 4: 378-383. 10.1016/S1479-666X(06)80114-9.CrossRefPubMed
9.
go back to reference Wiltz OH, Torregrosa M, Wiltz O: Autogenous vaccine: the best therapy for perianal condyloma acuminata?. Dis Colon Rectum. 1995, 38: 838-841. 10.1007/BF02049840.CrossRefPubMed Wiltz OH, Torregrosa M, Wiltz O: Autogenous vaccine: the best therapy for perianal condyloma acuminata?. Dis Colon Rectum. 1995, 38: 838-841. 10.1007/BF02049840.CrossRefPubMed
10.
go back to reference Govender PS: Atypical presentation of angiosarcoma of the scalp in the setting of human immunodeficiency virus (HIV). World J Surg Oncol. 2009, 7: 99-10.1186/1477-7819-7-99.CrossRefPubMedPubMedCentral Govender PS: Atypical presentation of angiosarcoma of the scalp in the setting of human immunodeficiency virus (HIV). World J Surg Oncol. 2009, 7: 99-10.1186/1477-7819-7-99.CrossRefPubMedPubMedCentral
11.
Metadata
Title
Giant condyloma acuminatum of the scrotum in a man with AIDS: a case report
Authors
Peter M Nthumba
Peter Ngure
Patrick Nyoro
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2011
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-5-272

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