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Published in: Journal of Medical Case Reports 1/2008

Open Access 01-12-2008 | Case report

Nail changes secondary to docetaxel chemotherapy : a case report

Authors: Qamar Ghafoor, Anula Chetiyawardana

Published in: Journal of Medical Case Reports | Issue 1/2008

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Abstract

Introduction

Docetaxel is a chemotherapy agent used in the management of many neoplastic conditions. Various side effects are known. Nail changes are often under-recognised or attributed to other causes.

Case presentation

We report the case of a 66 year old gentleman who received docetaxel chemotherapy for non-small cell lung cancer. He had nail changes as a complication of the treatment.

Conclusion

Nail toxicity is a recognised side-effect of taxane chemotherapy agents and can often persist for many months after finishing the treatment. We would like to highlight this problem, so it can be considered as a differential diagnosis in the appropriate population.
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Literature
2.
go back to reference Escobar PF, Rose PG: Docetaxel in ovarian cancer. Expert opin pharmacother. 2005, 6 (15): 2719-26. 10.1517/14656566.6.15.2719.CrossRefPubMed Escobar PF, Rose PG: Docetaxel in ovarian cancer. Expert opin pharmacother. 2005, 6 (15): 2719-26. 10.1517/14656566.6.15.2719.CrossRefPubMed
3.
go back to reference Vaishampayan U, Parchment RE, Jasti BR, Hussain M: Taxanes: an overview of the pharmacokinetics and pharmacodynamics. Urology. 1999, 54: 22-29. 10.1016/S0090-4295(99)00451-3.CrossRefPubMed Vaishampayan U, Parchment RE, Jasti BR, Hussain M: Taxanes: an overview of the pharmacokinetics and pharmacodynamics. Urology. 1999, 54: 22-29. 10.1016/S0090-4295(99)00451-3.CrossRefPubMed
4.
go back to reference Sobin LH, Wittekind C: International Union against Cancer; TNM: Classification of Malignant Tumors. 2002, New York, NY: Wiley-Liss, 6th edition. Sobin LH, Wittekind C: International Union against Cancer; TNM: Classification of Malignant Tumors. 2002, New York, NY: Wiley-Liss, 6th edition.
5.
go back to reference Spazzapon Simon, crivellari Diana, Lombardi Davide: Nail Toxicity related to weekly Taxanes: An important issue requiring a change in Common Toxicity Criteria Grading?. J Clin Oncol. 2002, 21: 4404-4405. 10.1200/JCO.2002.99.147.CrossRef Spazzapon Simon, crivellari Diana, Lombardi Davide: Nail Toxicity related to weekly Taxanes: An important issue requiring a change in Common Toxicity Criteria Grading?. J Clin Oncol. 2002, 21: 4404-4405. 10.1200/JCO.2002.99.147.CrossRef
Metadata
Title
Nail changes secondary to docetaxel chemotherapy : a case report
Authors
Qamar Ghafoor
Anula Chetiyawardana
Publication date
01-12-2008
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2008
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-2-24

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