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Open Access 01-12-2011 | Review

Anti-inflammatory and anti-infectious effects of Evodia rutaecarpa (Wuzhuyu) and its major bioactive components

Authors: Jyh-Fei Liao, Wen-Fei Chiou, Yuh-Chiang Shen, Guei-Jane Wang, Chieh-Fu Chen

Published in: Chinese Medicine | Issue 1/2011

Abstract

This article reviews the anti-inflammatory relative and anti-infectious effects of Evodia rutaecarpa and its major bioactive components and the involvement of the nitric oxide synthases, cyclooxygenase, NADPH oxidase, nuclear factor kappa B, hypoxia-inducible factor 1 alpha, reactive oxygen species, prostaglandins, tumor necrosis factor, LIGHT, amyloid protein and orexigenic neuropeptides. Their potential applications for the treatment of endotoxaemia, obesity, diabetes, Alzheimer's disease and their uses as cardiovascular and gastrointestinal protective agents, analgesics, anti-oxidant, anti-atherosclerosis agents, dermatological agents and anti-infectious agents are highlighted. Stimulation of calcitonin gene-related peptide release may partially explain the analgesic, cardiovascular and gastrointestinal protective, anti-obese activities of Evodia rutaecarpa and its major bioactive components.

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Title: Anti-inflammatory and anti-infectious effects of Evodia rutaecarpa (Wuzhuyu) and its major bioactive components
Authors: Jyh-Fei Liao
Wen-Fei Chiou
Yuh-Chiang Shen
Guei-Jane Wang
Chieh-Fu Chen
Publication date: 01-12-2011
Publisher: BioMed Central
Published in: Chinese Medicine / Issue 1/2011
Electronic ISSN: 1749-8546
DOI: https://doi.org/10.1186/1749-8546-6-6

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Anti-inflammatory and anti-infectious effects of Evodia rutaecarpa (Wuzhuyu) and its major bioactive components

Abstract

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

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