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Published in: Chinese Medicine 1/2010

Open Access 01-12-2010 | Review

Pharmacological effects of Salvia miltiorrhiza (Danshen) on cerebral infarction

Authors: Tsai-Hui Lin, Ching-Liang Hsieh

Published in: Chinese Medicine | Issue 1/2010

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Abstract

Danshen, the dried root of Salvia miltiorrhiza, is a Chinese medicine used to promote blood flow and treat vascular disease. The present article reviews the pharmacological effects of Danshen on cerebral infarction and possible interactions between Danshen and Western drugs. Danshen may reduce or prolong the development of atherosclerosis and may have anti-hypertensive and anti-platelet aggregation effects, which prevent cerebral infarction. Danshen may enhance endogenous anti-oxidative enzyme activities such as the expression of endothelial nitric oxide synthase and may scavenge oxygen free radicals. Prevention and treatment of cerebral infarction by Danshen involves multiple pathways, including anti-atherosclerosis, anti-hypertension, anti-platelet aggregation, anti-inflammatory and anti-oxidative effects.
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Metadata
Title
Pharmacological effects of Salvia miltiorrhiza (Danshen) on cerebral infarction
Authors
Tsai-Hui Lin
Ching-Liang Hsieh
Publication date
01-12-2010
Publisher
BioMed Central
Published in
Chinese Medicine / Issue 1/2010
Electronic ISSN: 1749-8546
DOI
https://doi.org/10.1186/1749-8546-5-22

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