Skip to main content
Top
Published in: Journal of Cardiothoracic Surgery 1/2012

Open Access 01-12-2012 | Case report

Löffler endocarditis: a rare cause of acute cardiac failure

Authors: Nicolasine D Niemeijer, Paul LA van Daele, Kadir Caliskan, Frans BS Oei, Olaf JL Loosveld, Nardo JM van der Meer

Published in: Journal of Cardiothoracic Surgery | Issue 1/2012

Login to get access

Abstract

We describe a patient with acute cardiogenic shock due to cardiac involvement in idiopathic hypereosinophilic syndrome (Löffler endocarditis). At the echocardiography, there was a huge mass in the left ventricular cavity, resulting in inflow- and outflow tract obstruction. The posterior leaflet of the mitral valve apparatus was completely embedded in a big (organized) thrombus mass. The patient was treated with high dose corticosteroids, however without effect. Partial remission was achieved after treatment with hydroxycarbamide. He was also treated with anticoagulants and high dose beta-blockers. The patient’s condition improved remarkably after correction of the mitral valve insufficiency by a mitral valve bioprosthesis.
Appendix
Available only for authorised users
Literature
1.
go back to reference Chusid MJ, Dale DC, West BC, Wolff SM: The hypereosinophilic syndrome: analysis of fourteen cases with review of the literature. Medicine (Baltimore). 1975, 54: 1-27. 10.1097/00005792-197501000-00001.CrossRef Chusid MJ, Dale DC, West BC, Wolff SM: The hypereosinophilic syndrome: analysis of fourteen cases with review of the literature. Medicine (Baltimore). 1975, 54: 1-27. 10.1097/00005792-197501000-00001.CrossRef
2.
go back to reference Tefferi A, Patnaik MM, Pardanani A: Eosinophilia: secondary, clonal and idiopathic. Br J Haematol. 2006, 133: 468-492. 10.1111/j.1365-2141.2006.06038.x.CrossRefPubMed Tefferi A, Patnaik MM, Pardanani A: Eosinophilia: secondary, clonal and idiopathic. Br J Haematol. 2006, 133: 468-492. 10.1111/j.1365-2141.2006.06038.x.CrossRefPubMed
3.
go back to reference Weller PF, Bubley GJ: The idiopathic hypereosinophilic syndrome. Blood. 1994, 83: 2759-2779.PubMed Weller PF, Bubley GJ: The idiopathic hypereosinophilic syndrome. Blood. 1994, 83: 2759-2779.PubMed
4.
go back to reference Cincin AA, Ozben B, Tanrikulu MA, Baskan O, Agirbasli M: Large apical thrombus in a patient with persistent heart failure and hypereosinophilia: Loffler endocarditis. J Gen Intern Med. 2008, 23: 1713-1718. 10.1007/s11606-008-0705-y.CrossRefPubMedPubMedCentral Cincin AA, Ozben B, Tanrikulu MA, Baskan O, Agirbasli M: Large apical thrombus in a patient with persistent heart failure and hypereosinophilia: Loffler endocarditis. J Gen Intern Med. 2008, 23: 1713-1718. 10.1007/s11606-008-0705-y.CrossRefPubMedPubMedCentral
5.
go back to reference Roufosse F, Cogan E, Goldman M: The hypereosinophilic syndrome revisited. Annu Rev Med. 2003, 54: 169-184. 10.1146/annurev.med.54.101601.152431.CrossRefPubMed Roufosse F, Cogan E, Goldman M: The hypereosinophilic syndrome revisited. Annu Rev Med. 2003, 54: 169-184. 10.1146/annurev.med.54.101601.152431.CrossRefPubMed
6.
go back to reference Fuzellier JF, Chapoutot L, Torossian PF, Metz D, Baehrel B: Mitral valve replacement in idiopathic eosinophilic endocarditis without peripheral eosinophilia. J Card Surg. 2005, 20: 472-474. 10.1111/j.1540-8191.2005.200460.x.CrossRefPubMed Fuzellier JF, Chapoutot L, Torossian PF, Metz D, Baehrel B: Mitral valve replacement in idiopathic eosinophilic endocarditis without peripheral eosinophilia. J Card Surg. 2005, 20: 472-474. 10.1111/j.1540-8191.2005.200460.x.CrossRefPubMed
7.
go back to reference Sasano H, Virmani R, Patterson RH, Robinowitz M, Guccion JG: Eosinophilic products lead to myocardial damage. Hum Pathol. 1989, 20: 850-857. 10.1016/0046-8177(89)90096-8.CrossRefPubMed Sasano H, Virmani R, Patterson RH, Robinowitz M, Guccion JG: Eosinophilic products lead to myocardial damage. Hum Pathol. 1989, 20: 850-857. 10.1016/0046-8177(89)90096-8.CrossRefPubMed
8.
go back to reference Hendren WG, Jones EL, Smith MD: Aortic and mitral valve replacement in idiopathic hypereosinophilic syndrome. Ann Thorac Surg. 1988, 46: 570-571. 10.1016/S0003-4975(10)64701-7.CrossRefPubMed Hendren WG, Jones EL, Smith MD: Aortic and mitral valve replacement in idiopathic hypereosinophilic syndrome. Ann Thorac Surg. 1988, 46: 570-571. 10.1016/S0003-4975(10)64701-7.CrossRefPubMed
9.
go back to reference Tanino M, Kitamura K, Ohta G, Yamamoto Y, Sugioka G: Hypereosinophilic syndrome with extensive myocardial involvement and mitral valve thrombus instead of mural thrombi. Acta Pathol Jpn. 1983, 33: 1233-1242.PubMed Tanino M, Kitamura K, Ohta G, Yamamoto Y, Sugioka G: Hypereosinophilic syndrome with extensive myocardial involvement and mitral valve thrombus instead of mural thrombi. Acta Pathol Jpn. 1983, 33: 1233-1242.PubMed
10.
go back to reference Benezet-Mazuecos J, Marcos-Alberca P, Farre J, Orejas M, de la Fuente A, Prieto E: Early differential resolution of right and left ventricular obliteration in Löffler endocarditis after chemotherapy and anticoagulation. Circulation. 2006, 114: e635-e637. 10.1161/CIRCULATIONAHA.106.636753.CrossRefPubMed Benezet-Mazuecos J, Marcos-Alberca P, Farre J, Orejas M, de la Fuente A, Prieto E: Early differential resolution of right and left ventricular obliteration in Löffler endocarditis after chemotherapy and anticoagulation. Circulation. 2006, 114: e635-e637. 10.1161/CIRCULATIONAHA.106.636753.CrossRefPubMed
11.
go back to reference ten Oever J, Theunissen LJHJ, Tick LW, Verbunt RJAM: Cardiac involvement in hypereosinophilic syndrome. Neth J Med. 2011, 69: 240-244.PubMed ten Oever J, Theunissen LJHJ, Tick LW, Verbunt RJAM: Cardiac involvement in hypereosinophilic syndrome. Neth J Med. 2011, 69: 240-244.PubMed
12.
go back to reference Bozcali E, Aliyev F, Agac MT, Erkan H, Okcun B, Babalik E, Karpuz H: Unusual case of aortic valve involvement in patient with Loffler’s endomyocarditis: management, follow-up and short review of the literature. J Thromb Thrombolysis. 2007, 24: 309-313. 10.1007/s11239-007-0029-5.CrossRefPubMed Bozcali E, Aliyev F, Agac MT, Erkan H, Okcun B, Babalik E, Karpuz H: Unusual case of aortic valve involvement in patient with Loffler’s endomyocarditis: management, follow-up and short review of the literature. J Thromb Thrombolysis. 2007, 24: 309-313. 10.1007/s11239-007-0029-5.CrossRefPubMed
13.
go back to reference Yoon TY, Ahn GB, Chang SH: Complete remission of hypereosinophilic syndrome after interferon-alpha therapy: report of a case and literature review. J Dermatol. 2000, 27: 110-115.CrossRefPubMed Yoon TY, Ahn GB, Chang SH: Complete remission of hypereosinophilic syndrome after interferon-alpha therapy: report of a case and literature review. J Dermatol. 2000, 27: 110-115.CrossRefPubMed
14.
go back to reference Fauci AS, Harley JB, Roberts WC, Ferrans VJ, Gralnick HR, Bjornson BH: NIH conference. the idiopathic hypereosinophilic syndrome. clinical, pathophysiologic, and therapeutic considerations. Ann Intern Med. 1982, 97: 78-92.CrossRefPubMed Fauci AS, Harley JB, Roberts WC, Ferrans VJ, Gralnick HR, Bjornson BH: NIH conference. the idiopathic hypereosinophilic syndrome. clinical, pathophysiologic, and therapeutic considerations. Ann Intern Med. 1982, 97: 78-92.CrossRefPubMed
15.
go back to reference Tefferi A: Modern diagnosis and treatment of primary eosinophilia. Acta Haematol. 2005, 114: 52-60. 10.1159/000085562.CrossRefPubMed Tefferi A: Modern diagnosis and treatment of primary eosinophilia. Acta Haematol. 2005, 114: 52-60. 10.1159/000085562.CrossRefPubMed
16.
go back to reference Kahn JE, Bletry O, Guillevin L: Hypereosinophilic syndromes. Best Pract Res Clin Rheumatol. 2008, 22: 863-882. 10.1016/j.berh.2008.09.010.CrossRefPubMed Kahn JE, Bletry O, Guillevin L: Hypereosinophilic syndromes. Best Pract Res Clin Rheumatol. 2008, 22: 863-882. 10.1016/j.berh.2008.09.010.CrossRefPubMed
17.
go back to reference Antoniu SA: Novel therapies for hypereosinophilic syndromes. Neth J Med. 2010, 68: 304-310.PubMed Antoniu SA: Novel therapies for hypereosinophilic syndromes. Neth J Med. 2010, 68: 304-310.PubMed
18.
go back to reference Wilkins HJ, Crane MM, Copeland K, Williams WV: Hypereosinophilic syndrome: an update. Am J Hematol. 2005, 80: 148-157. 10.1002/ajh.20423.CrossRefPubMed Wilkins HJ, Crane MM, Copeland K, Williams WV: Hypereosinophilic syndrome: an update. Am J Hematol. 2005, 80: 148-157. 10.1002/ajh.20423.CrossRefPubMed
19.
go back to reference Ueno NT, Anagnostopoulos A, Rondón G, Champlin RE, Mikhailova N, Pankratova OS, Zoubarovskaya LS, Semenova EV, Afanasyev BV, O’Brien S, Andreeff M, Zaritskey AY: Successful non-myeloablative allogeneic transplantation for treatment of idiopathic hypereosinophilic syndrome. Br J Haematol. 2002, 119: 131-134. 10.1046/j.1365-2141.2002.03771.x.CrossRefPubMed Ueno NT, Anagnostopoulos A, Rondón G, Champlin RE, Mikhailova N, Pankratova OS, Zoubarovskaya LS, Semenova EV, Afanasyev BV, O’Brien S, Andreeff M, Zaritskey AY: Successful non-myeloablative allogeneic transplantation for treatment of idiopathic hypereosinophilic syndrome. Br J Haematol. 2002, 119: 131-134. 10.1046/j.1365-2141.2002.03771.x.CrossRefPubMed
20.
go back to reference Cooper MA, Akard LP, Thompson JM, Dugan MJ, Jansen J: Hypereosinophilic syndrome: long-term remission following allogeneic stem cell transplant in spite of transient eosinophilia post-transplant. Am J Hematol. 2005, 78: 33-36. 10.1002/ajh.20214.CrossRefPubMed Cooper MA, Akard LP, Thompson JM, Dugan MJ, Jansen J: Hypereosinophilic syndrome: long-term remission following allogeneic stem cell transplant in spite of transient eosinophilia post-transplant. Am J Hematol. 2005, 78: 33-36. 10.1002/ajh.20214.CrossRefPubMed
21.
go back to reference Boustany CW, Murphy GW, Hicks GL: Mitral valve replacement in idiopathic hypereosinophilic syndrome. Ann Thorac Surg. 1991, 51: 1007-1009. 10.1016/0003-4975(91)91034-S.CrossRefPubMed Boustany CW, Murphy GW, Hicks GL: Mitral valve replacement in idiopathic hypereosinophilic syndrome. Ann Thorac Surg. 1991, 51: 1007-1009. 10.1016/0003-4975(91)91034-S.CrossRefPubMed
Metadata
Title
Löffler endocarditis: a rare cause of acute cardiac failure
Authors
Nicolasine D Niemeijer
Paul LA van Daele
Kadir Caliskan
Frans BS Oei
Olaf JL Loosveld
Nardo JM van der Meer
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Journal of Cardiothoracic Surgery / Issue 1/2012
Electronic ISSN: 1749-8090
DOI
https://doi.org/10.1186/1749-8090-7-109

Other articles of this Issue 1/2012

Journal of Cardiothoracic Surgery 1/2012 Go to the issue