Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Journal of Thrombosis and Thrombolysis
Published in: Journal of Thrombosis and Thrombolysis 3/2007

01-12-2007

Unusual case of aortic valve involvement in patient with Löffler’s Endomyocarditis: management, follow-up and short review of the literature

Authors: Evin Bozcali, Farid Aliyev, Mustafa Tarik Agac, Hakan Erkan, Barıs Okcun, Erhan Babalik, Hakan Karpuz

Published in: Journal of Thrombosis and Thrombolysis | Issue 3/2007

Login to get access

Abstract

Idiopathic hypereosinophilic syndrome (IHES) is an uncommon systemic disease which is characterised by blood eosinophilia and multiple clinical presentations. Cardiac involvement is the major cause of mortality and morbidity. Here we describe a 59-year-old man with symptoms of progressive dyspnea on exertion, and productive cough as an unusual case of Löffler endomyocarditis with a mass on the aortic valve which showed regression with treatment.
Literature
1.
Dauphin C, Motreff P, Ruivard M, Rieu V, Cloix JJ, Lamaison D, Cassagnes J, Lusson JR (2005) Regressive aortic valve and infundibular tumors during idiopathic hypereosinophilic syndrome. J Am Soc Echocardiogr 18(7):772aCrossRef
2.
Loffler W (1936) Endocarditis parietalis fibroplastica mit bluteosinophilie. Ein eigenartiges Krankheitsbild. Schweiz Med Wochenschr 66:817–820
3.
Weller P, Bubley G (1994) The idiopathic hypereosinophilic syndrome. Blood 83(10):2759–2779PubMed
4.
Parrillo JE, Borer JS, Henry WL, Wolff SM, Fauci AS (1979) The cardiovascular manifestations of the hypereosinophilic syndrome. Prospective study of 26 patients with review of the literature. Am J Med 67(4):572–582PubMedCrossRef
5.
Shah RS, Ananthasubramaniam K (2006) Evaluation of cardiac involvement in hypereosinophilic syndrome: complementary roles of transthoracic, transesopageal, and contrast echocardiography. Echocardiography 23(8):689–691PubMedCrossRef
6.
Gudmundsson GS, Ohr J, Leya F, Jacops WR, Godwin JE, Schwartz J (2003) An unusual case of recurrent Loffler endomyocarditis of the aortic valve. Arch Pathol Lab Med 127(5):606–609PubMed
7.
Hendren WG, Jones EL, Smith MD (1988) Aortic and mitral valve replacement in idiopathic hypereosinophilic syndrome. Ann Thorac Surg 46:570–571PubMedCrossRef
8.
Smith MD, Metcalfe M, DeMaria AN, Hendren WG, Walter PF, Jones EL (1989) Hypereosinophilic syndrome resulting in aortic and mitral stenosis: a case requiring double valve replacement. Am Heart J 117(2):475–479PubMedCrossRef
9.
Fauci AS, Harley JB, Roberts WC, Ferrans VJ, Gralnick HR, Bjornson BH (1982) NIH conference. The idiopathic hypereosinophilic syndrome Clinical pathophysiologic and therapeutic considerations. Ann Intern Med 97(1):78–92PubMed
10.
Assa’ad AH, Spicer RL, Nelson DP, Zimmermann N, Rothenberg ME (2000) Hypereosinophilic syndromes. Chem Immunol 76:208–229PubMedCrossRef
11.
Parrillo JE, Fauci AS, Wolff SM (1978) Therapy of the hypereosinophilic syndrome. Ann Intern Med 89:167–172PubMed
12.
Cortes J, Ault P, Koller C, Thomas D, Ferrajoli A, Wierda W, Rios MB, Letvak L, Kaled ES, Kantarjian H (2003) Efficacy of imatinib mesylate in the treatment of idiopathic hypereosinophilic syndrome. Blood 101:4714–4716PubMedCrossRef
13.
Anghel G, De rosa L, Ruscio C, Petti N, Riccardi M, Severino A, Majolino I (2005) Efficay of imatinib mesylate in a patient with idiopathic hypereosinophilic syndrome and severe involvement. Tumori 91(1):67–70PubMed
14.
Radford DJ, Garlick RB, Pohlner PG (2002) Multiple valvar replacements for hypereosinophilic syndrome. Cardiol Young 12(1):67–70PubMedCrossRef
15.
Fuzeller JF, Chapoutot L, Torossian PF, Metz D, Baehrel B (2005) Mitral valve replacement in idiopathic eosinophilic endocarditis without peripheral eosinophilia. J Card Surg 20(5):472–474CrossRef
16.
Mazuecos JB, Alberca PM, Farre J, Orejas M, Fuente A, Prieto E (2006) Early differential resolution of right and left ventricular obliteration in Löffler Endocarditis after chemotherapy and anticoagulation. Circulation 114:e635–e637CrossRef
17.
Menzel T, Lambertz H, Rau G (1992) Cardiac involvement in the hypereosinophilia syndrome. The importance of echocardiography in the follow-up. Dtsch Med Wochenschr 117(40):1518–1524PubMedCrossRef
18.
Bunc M, Remskar Z, Brucan A (2001) The idiopathic hypereosinophilic syndrome. Eur J Emerg Med 8(4):325–330PubMedCrossRef
Metadata
Title
Unusual case of aortic valve involvement in patient with Löffler’s Endomyocarditis: management, follow-up and short review of the literature
Authors
Evin Bozcali
Farid Aliyev
Mustafa Tarik Agac
Hakan Erkan
Barıs Okcun
Erhan Babalik
Hakan Karpuz
Publication date
01-12-2007
Publisher
Springer US
Published in
Journal of Thrombosis and Thrombolysis / Issue 3/2007
Print ISSN: 0929-5305
Electronic ISSN: 1573-742X
DOI
https://doi.org/10.1007/s11239-007-0029-5

Other articles of this Issue 3/2007

Journal of Thrombosis and Thrombolysis 3/2007 Go to the issue

OriginalPaper

Relation between impaired antiplatelet response to clopidogrel and possible pleiotropic effects

OriginalPaper

Inhibition of collagen, and thrombin-induced platelet aggregation by Lansberg’s hognose pit viper (Porthidium lansbergii hutmanni) venom

OriginalPaper

Increased Factor V Leiden frequency is associated with venous thrombotic events among young Brazilian patients

OriginalPaper

A five-year, retrospective, comparison review of survival in neurosurgical patients diagnosed with venous thromboembolism and treated with either inferior vena cava filters or anticoagulants

OriginalPaper

Inferior vena caval tumor thrombus extending into the right atrium in a patient with pancreatic cancer

OriginalPaper

Routine upstream versus selective down stream use of tirofiban in non-ST elevation myocardial infarction patients scheduled for early invasive therapy; a randomized comparison
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Pediatric Cardiology Video

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

Cardiopulmonary Comorbidity Video

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Valvular Heart Disease Video

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits