Published in:
Open Access
01-12-2008 | Research article
Protective efficiacy of taurine against pulmonary edema progression: experimental study
Authors:
Orhan Yucel, Zeki Ilker Kunak, Enis Macit, Armagan Gunal, Alper Gozubuyuk, Husamettin Gul, Onur Genc
Published in:
Journal of Cardiothoracic Surgery
|
Issue 1/2008
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Abstract
Re-expansion pulmonary edema (RPE) is an acute, rare and potentially lethal complication [1,2]. Its beginning is sudden and dramatic. The mechanism is not yet fully understood [1]. Some authors suggest that it may occur after rapid re-inflation of a collapsed lung [1]. It was reported by other authors that it may relate to surfactant depletion or may result from hypoxic capillary damage, leading to increased capillary permeability [1,3]. In RPE, unilateral lung injury is initiated by cytotoxic oxygen metabolites and temporally associated with an influx of polymorphonuclear neutrophils [1]. These toxic oxygen products are the results of re-oxygenation of a collapsed lung. Treatment of re-expansion pulmonary edema is basically preventive [4].