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Published in: Journal of Cardiothoracic Surgery 1/2008

Open Access 01-12-2008 | Research article

Protective efficiacy of taurine against pulmonary edema progression: experimental study

Authors: Orhan Yucel, Zeki Ilker Kunak, Enis Macit, Armagan Gunal, Alper Gozubuyuk, Husamettin Gul, Onur Genc

Published in: Journal of Cardiothoracic Surgery | Issue 1/2008

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Abstract

Re-expansion pulmonary edema (RPE) is an acute, rare and potentially lethal complication [1,2]. Its beginning is sudden and dramatic. The mechanism is not yet fully understood [1]. Some authors suggest that it may occur after rapid re-inflation of a collapsed lung [1]. It was reported by other authors that it may relate to surfactant depletion or may result from hypoxic capillary damage, leading to increased capillary permeability [1,3]. In RPE, unilateral lung injury is initiated by cytotoxic oxygen metabolites and temporally associated with an influx of polymorphonuclear neutrophils [1]. These toxic oxygen products are the results of re-oxygenation of a collapsed lung. Treatment of re-expansion pulmonary edema is basically preventive [4].
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Metadata
Title
Protective efficiacy of taurine against pulmonary edema progression: experimental study
Authors
Orhan Yucel
Zeki Ilker Kunak
Enis Macit
Armagan Gunal
Alper Gozubuyuk
Husamettin Gul
Onur Genc
Publication date
01-12-2008
Publisher
BioMed Central
Published in
Journal of Cardiothoracic Surgery / Issue 1/2008
Electronic ISSN: 1749-8090
DOI
https://doi.org/10.1186/1749-8090-3-57

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