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Open Access 01-12-2008 | Research article

Double vs single internal thoracic artery harvesting in diabetic patients: role in perioperative infection rate

Authors: Marco Agrifoglio, Matteo Trezzi, Fabio Barili, Luca Dainese, Faisal H Cheema, Veli K Topkara, Chiara Ghislandi, Alessandro Parolari, Gianluca Polvani, Francesco Alamanni, Paolo Biglioli

Published in: Journal of Cardiothoracic Surgery | Issue 1/2008

Abstract

Background

The aim of this prospective study is to evaluate the role in the onset of surgical site infections of bilateral internal thoracic arteries harvesting in patients with decompensated preoperative glycemia.

Methods

81 consecutive patients with uncontrolled diabetes mellitus underwent elective CABG harvesting single or double internal thoracic arteries. Single left ITA was harvested in 41 patients (Group 1, 50.6%), BITAs were harvested in 40 (Group 2, 49.4%). The major clinical end points analyzed in this study were infection rate, type of infection, duration of infection, infection relapse rate and total hospital length of stay.

Results

Five patients developed sternal SSI in the perioperative period, 2 in group 1 and 3 in group 2 without significant difference. All sternal SSIs were superficial with no sternal dehiscence. The development of infection from the time of surgery took 18.5 ± 2.1 and 7.3 ± 3.0 days for Groups 1 and 2 respectively. The infections were treated with wound irrigation and debridement, and with VAC therapy as well as with antibiotics. The VAC system was removed after a mean of 12.8 ± 5.1 days, when sterilization was achieved. The overall survival estimate at 1 year was 98.7%. Only BMI was a significant predictor of SSI using multivariate stepwise logistic regression analysis (Odds Ratio: 1.34; 95%Conficdence Interval: 1.02–1.83; p value: 0.04). In the model, the use of BITA was not an independent predictor of SSI.

Conclusion

CABG with bilateral pedicled ITAs grafting could be performed safely even in diabetics with poor preoperative glycaemic control.

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Title: Double vs single internal thoracic artery harvesting in diabetic patients: role in perioperative infection rate
Authors: Marco Agrifoglio
Matteo Trezzi
Fabio Barili
Luca Dainese
Faisal H Cheema
Veli K Topkara
Chiara Ghislandi
Alessandro Parolari
Gianluca Polvani
Francesco Alamanni
Paolo Biglioli
Publication date: 01-12-2008
Publisher: BioMed Central
Published in: Journal of Cardiothoracic Surgery / Issue 1/2008
Electronic ISSN: 1749-8090
DOI: https://doi.org/10.1186/1749-8090-3-35

At a glance: The STEP trials

Springer Medicine

Double vs single internal thoracic artery harvesting in diabetic patients: role in perioperative infection rate

Abstract

Background

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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