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Published in: World Journal of Emergency Surgery 1/2006

Open Access 01-12-2006 | Case report

A case report of a new pulmonary embolism occurring in a patient receiving continuous infusion of recombinant activated protein C

Authors: Bernard J Benedetto, Michael A Houston

Published in: World Journal of Emergency Surgery | Issue 1/2006

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Abstract

Background

There are no guidelines governing the concomitant use of recombinant human activated protein C (rhAPC) and deep venous thrombosis/pulmonary embolism (DVT/PE) prophylaxis in critically ill patients. It is unknown if rhAPC provides any protection against DVT/PE in this population of patients.

Methods

Case report.

Results

This report describes the first case of a radiographically demonstrated pulmonary embolism occurring in a patient receiving continuous therapeutic infusion of rhAPC.

Conclusion

The administration of rhAPC alone may not be sufficient DVT/PE prophylaxis in high risk patients. The risks associated with concomitant anticoagulation and rhAPC therapy are unknown. Further research is necessary to determine the safest and most effective regimen for DVT/PE prophylaxis in patients receiving rhAPC.
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Metadata
Title
A case report of a new pulmonary embolism occurring in a patient receiving continuous infusion of recombinant activated protein C
Authors
Bernard J Benedetto
Michael A Houston
Publication date
01-12-2006
Publisher
BioMed Central
Published in
World Journal of Emergency Surgery / Issue 1/2006
Electronic ISSN: 1749-7922
DOI
https://doi.org/10.1186/1749-7922-1-23

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