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Diagnostic Pathology
Published in: Diagnostic Pathology 1/2014

Open Access 01-12-2014 | Case Report

A case report of seronegative cat scratch disease, emphasizing the histopathologic point of view

Authors: Ok Ran Shin, Yang Ree Kim, Tae-hyun Ban, Taeseok Lim, Tae Hee Han, Su Yeon Kim, Kyung Jin Seo

Published in: Diagnostic Pathology | Issue 1/2014

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Abstract

Cat scratch disease, necrotizing granulomatous lymphadenitis caused by Bartonella henselae, usually benign and self-limited. However, various clinical manifestations and no pathognomonic histopathologic features can lead to misinterpretations and diagnostic disputes. We report a case of cat scratch disease in a 39-yr-old male patient with fever and left axillary lymphadenitis. He had a history of cat bite on the left hand dorsum. On excision, the lymph node showed follicular hyperplasia, stellate microabscesses with a rim of granulomatous inflammation. Warthin-Starry silver staining showed many clumps of silver-stained bacilli within the necrotic foci. Serological tests were negative. Diagnosis was established by PCR analysis.

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Metadata
Title
A case report of seronegative cat scratch disease, emphasizing the histopathologic point of view
Authors
Ok Ran Shin
Yang Ree Kim
Tae-hyun Ban
Taeseok Lim
Tae Hee Han
Su Yeon Kim
Kyung Jin Seo
Publication date
01-12-2014
Publisher
BioMed Central
Published in
Diagnostic Pathology / Issue 1/2014
Electronic ISSN: 1746-1596
DOI
https://doi.org/10.1186/1746-1596-9-62

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