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Molecular Pain
Published in: Molecular Pain 1/2009

Open Access 01-12-2009 | Review

Challenges of functional imaging research of pain in children

Authors: Simona Sava, Alyssa A Lebel, David S Leslie, Athena Drosos, Charles Berde, Lino Becerra, David Borsook

Published in: Molecular Pain | Issue 1/2009

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Abstract

Functional imaging has revolutionized the neurosciences. In the pain field it has dramatically altered our understanding of how the brain undergoes significant functional, anatomical and chemical changes in patients with chronic pain. However, most studies have been performed in adults. Because functional imaging is non-invasive and can be performed in awake individuals, applications in children have become more prevalent, but only recently in the pain field. Measures of changes in the brains of children have important implications in understanding neural plasticity in response to acute and chronic pain in the developing brain. Such findings may have implications for treatments in children affected by chronic pain and provide novel insights into chronic pain syndromes in adults. In this review we summarize this potential and discuss specific concerns related to the imaging of pain in children.
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Metadata
Title
Challenges of functional imaging research of pain in children
Authors
Simona Sava
Alyssa A Lebel
David S Leslie
Athena Drosos
Charles Berde
Lino Becerra
David Borsook
Publication date
01-12-2009
Publisher
BioMed Central
Published in
Molecular Pain / Issue 1/2009
Electronic ISSN: 1744-8069
DOI
https://doi.org/10.1186/1744-8069-5-30

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