Published in:
Open Access
01-12-2010 | Short report
NSP2 gene variation of the North American genotype of the Thai PRRSV in central Thailand
Authors:
Roongtham Kedkovid, Suparlark Nuntawan Na Ayudhya, Alongkorn Amonsin, Roongroje Thanawongnuwech
Published in:
Virology Journal
|
Issue 1/2010
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Abstract
Porcine reproductive and respiratory syndrome virus (PRRSV) is a major swine pathogen causing economic losses in the swine industry almost worldwide. PRRSV has been divided into 2 genotypes, the European (Type 1) and North American (Type 2) genotype, respectively and displays a large degree of genetic variability, particularly at the nonstructural protein (nsp) 2 gene. This is the first study determining genetic variation of the nsp2 of Thai PRRSV isolates. The results showed that 9 out of 10 Thai PRRSV isolates were nsp2-truncated viruses that might have evolved from a virus previously introduced in the past, but not from one recently introduced.