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Published in: Virology Journal 1/2009

Open Access 01-12-2009 | Case Report

Phylogenetic analysis and characterization of Korean orf virus from dairy goats: case report

Authors: Jae-Ku Oem, In-Soon Roh, Kyung-Hyun Lee, Kyoung-Ki Lee, Hye-Ryoung Kim, Young-Hwa Jean, O-Soo Lee

Published in: Virology Journal | Issue 1/2009

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Abstract

An outbreak of orf virus infection in dairy goats in Korea was investigated. Suspected samples of the skin and lip of affected goats were sent to the laboratory for more exact diagnosis. Orf virus was detected by electron microscopy and viral DNA was identified by PCR. To reveal the genetic characteristics of the Korean strain (ORF/09/Korea), the sequences of the major envelope protein (B2L) and orf virus interferon resistance (VIR) genes were determined and then compared with published reference sequences. Phylogenetic analysis revealed that the ORF/09/Korea strain was closest to the isolates (Taiping) from Taiwan. This is believed to be the first report on the molecular characterization of orf virus in Korea.
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Literature
1.
go back to reference Robinson AJ, Balassu TC: Contagious pustular dermatitis (orf). Vet Bull 1981, 51: 771-82. Robinson AJ, Balassu TC: Contagious pustular dermatitis (orf). Vet Bull 1981, 51: 771-82.
2.
go back to reference Haig DM, Thomson J, Mclnnes C, McCaughan C, Imlach W, Mercer A, Fleming S: Orf virus immuno-modulation and the host immune response. Vet Immunol Immunopathol 2002, 87: 395-99. 10.1016/S0165-2427(02)00087-9CrossRefPubMed Haig DM, Thomson J, Mclnnes C, McCaughan C, Imlach W, Mercer A, Fleming S: Orf virus immuno-modulation and the host immune response. Vet Immunol Immunopathol 2002, 87: 395-99. 10.1016/S0165-2427(02)00087-9CrossRefPubMed
3.
4.
go back to reference Hosamani M, Bhanuprakash V, Scagliarini A, Singh RK: Comparative sequence analysis of major envelope protein gene (B2L) of Indian orf viruses isolated from sheep and goats. Vet Microbiol 2006, 116: 317-24. 10.1016/j.vetmic.2006.04.028CrossRefPubMed Hosamani M, Bhanuprakash V, Scagliarini A, Singh RK: Comparative sequence analysis of major envelope protein gene (B2L) of Indian orf viruses isolated from sheep and goats. Vet Microbiol 2006, 116: 317-24. 10.1016/j.vetmic.2006.04.028CrossRefPubMed
5.
go back to reference Guo J, Zhang Z, Edwards JF, Ermel RW, Taylor C Jr, de la Concha-Bermejillo A: Characterization of a North American orf virus isolated from a goat with persistent, proliferative dermatitis. Virus Res 2003, 93: 169-79. 10.1016/S0168-1702(03)00095-9CrossRefPubMed Guo J, Zhang Z, Edwards JF, Ermel RW, Taylor C Jr, de la Concha-Bermejillo A: Characterization of a North American orf virus isolated from a goat with persistent, proliferative dermatitis. Virus Res 2003, 93: 169-79. 10.1016/S0168-1702(03)00095-9CrossRefPubMed
6.
go back to reference Chan KW, Lin JW, Lee SH, Liao CJ, Tsai MC, Hsu WL, Wong ML, Shih HC: Identification and phylogenetic analysis of orf virus from goats in Taiwan. Virus Genes 2007, 35: 705-12. 10.1007/s11262-007-0144-6CrossRefPubMed Chan KW, Lin JW, Lee SH, Liao CJ, Tsai MC, Hsu WL, Wong ML, Shih HC: Identification and phylogenetic analysis of orf virus from goats in Taiwan. Virus Genes 2007, 35: 705-12. 10.1007/s11262-007-0144-6CrossRefPubMed
7.
go back to reference Kottaridi C, Nomikou K, Teodori L, Savini G, Lelli R, Markoulatos P, Mangana O: Phylogenetic correlation of Greek and Italian orf virus isolates based on VIR gene. Vet Microbiol 2006, 116: 310-16. 10.1016/j.vetmic.2006.04.020CrossRefPubMed Kottaridi C, Nomikou K, Teodori L, Savini G, Lelli R, Markoulatos P, Mangana O: Phylogenetic correlation of Greek and Italian orf virus isolates based on VIR gene. Vet Microbiol 2006, 116: 310-16. 10.1016/j.vetmic.2006.04.020CrossRefPubMed
8.
go back to reference Mondal B, Bera AK, Hosamani M, Tembhurne PA, Bandyopadhyay SK: Detection of Orf virus from an outbreak in goats and its genetic relation with other parapoxviruses. Vet Res Commun 2006, 30: 531-39. 10.1007/s11259-006-3270-zCrossRefPubMed Mondal B, Bera AK, Hosamani M, Tembhurne PA, Bandyopadhyay SK: Detection of Orf virus from an outbreak in goats and its genetic relation with other parapoxviruses. Vet Res Commun 2006, 30: 531-39. 10.1007/s11259-006-3270-zCrossRefPubMed
9.
go back to reference Zheng M, Liu Q, Jin N, Guo J, Huang X, Li H, Zhu W, Xiong Y: A duplex PCR assay for simultaneous detection and differentiation of capripoxvirus and orf virus. Mol Cell Probes 2007, 21: 276-81. 10.1016/j.mcp.2007.01.005CrossRefPubMed Zheng M, Liu Q, Jin N, Guo J, Huang X, Li H, Zhu W, Xiong Y: A duplex PCR assay for simultaneous detection and differentiation of capripoxvirus and orf virus. Mol Cell Probes 2007, 21: 276-81. 10.1016/j.mcp.2007.01.005CrossRefPubMed
10.
go back to reference Kumar S, Tamura K, Nei M: MEGA3: integrated software for molecular evolutionary genetics analysis and sequence alignment. Brief Bioinform 2004, 5: 150-63. 10.1093/bib/5.2.150CrossRefPubMed Kumar S, Tamura K, Nei M: MEGA3: integrated software for molecular evolutionary genetics analysis and sequence alignment. Brief Bioinform 2004, 5: 150-63. 10.1093/bib/5.2.150CrossRefPubMed
11.
go back to reference Inoshima Y, Morooka A, Sentsui H: Detection and diagnosis of parapoxvirus by the polymerase chain reaction. J Virol Methods 2000, 84: 201-208. 10.1016/S0166-0934(99)00144-5CrossRefPubMed Inoshima Y, Morooka A, Sentsui H: Detection and diagnosis of parapoxvirus by the polymerase chain reaction. J Virol Methods 2000, 84: 201-208. 10.1016/S0166-0934(99)00144-5CrossRefPubMed
12.
go back to reference Chan KW, Hsu WL, Wang CY, Yang CH, Lin FY, Chulakasian S, Wong ML: Differential diagnosis of orf viruses by a single-step PCR. J Virol Methods 2009, 160: 85-9. 10.1016/j.jviromet.2009.04.025CrossRefPubMed Chan KW, Hsu WL, Wang CY, Yang CH, Lin FY, Chulakasian S, Wong ML: Differential diagnosis of orf viruses by a single-step PCR. J Virol Methods 2009, 160: 85-9. 10.1016/j.jviromet.2009.04.025CrossRefPubMed
13.
go back to reference Sullivan JT, Mercer AA, Fleming SB, Robinson AJ: Identification and characterization of an orf virus homologue of the vaccinia virus gene encoding the major envelope antigen p37K. Virol 1994, 202: 968-73. 10.1006/viro.1994.1420CrossRef Sullivan JT, Mercer AA, Fleming SB, Robinson AJ: Identification and characterization of an orf virus homologue of the vaccinia virus gene encoding the major envelope antigen p37K. Virol 1994, 202: 968-73. 10.1006/viro.1994.1420CrossRef
14.
go back to reference Delhon G, Tulman ER, Afonso CL, Lu Z, de la Concha-Bermejillo A, Lehmkuhl HD, Piccone ME, Kutish GF, Rock DL: Genomes of the parapoxviruses ORF virus and bovine papular stomatitis virus. J Virol 2004, 78: 168-77. 10.1128/JVI.78.1.168-177.2004PubMedCentralCrossRefPubMed Delhon G, Tulman ER, Afonso CL, Lu Z, de la Concha-Bermejillo A, Lehmkuhl HD, Piccone ME, Kutish GF, Rock DL: Genomes of the parapoxviruses ORF virus and bovine papular stomatitis virus. J Virol 2004, 78: 168-77. 10.1128/JVI.78.1.168-177.2004PubMedCentralCrossRefPubMed
15.
go back to reference Mercer AA, Ueda N, Friederichs SM, Hofmann K, Fraser KM, Bateman T, Fleming SB: Comparative analysis of genome sequences of three isolates of Orf virus reveals unexpected sequence variation. Virus Res 2006, 116: 146-58.CrossRefPubMed Mercer AA, Ueda N, Friederichs SM, Hofmann K, Fraser KM, Bateman T, Fleming SB: Comparative analysis of genome sequences of three isolates of Orf virus reveals unexpected sequence variation. Virus Res 2006, 116: 146-58.CrossRefPubMed
16.
go back to reference McInnes CJ, Wood AR, Mercer AA: Orf virus encodes a homolog of the vaccinia virus interferon-resistance gene E3L. Virus Genes 1998, 17: 107-15. 10.1023/A:1026431704679CrossRefPubMed McInnes CJ, Wood AR, Mercer AA: Orf virus encodes a homolog of the vaccinia virus interferon-resistance gene E3L. Virus Genes 1998, 17: 107-15. 10.1023/A:1026431704679CrossRefPubMed
17.
go back to reference Chan KW, Yang CH, Lin JW, Wang HC, Lin FY, Kuo ST, Wong ML, Hsu WL: Phylogenetic analysis of parapoxviruses and the C-terminal heterogeneity of viral ATPase proteins. Gene 2009, 432: 44-53. 10.1016/j.gene.2008.10.029CrossRefPubMed Chan KW, Yang CH, Lin JW, Wang HC, Lin FY, Kuo ST, Wong ML, Hsu WL: Phylogenetic analysis of parapoxviruses and the C-terminal heterogeneity of viral ATPase proteins. Gene 2009, 432: 44-53. 10.1016/j.gene.2008.10.029CrossRefPubMed
Metadata
Title
Phylogenetic analysis and characterization of Korean orf virus from dairy goats: case report
Authors
Jae-Ku Oem
In-Soon Roh
Kyung-Hyun Lee
Kyoung-Ki Lee
Hye-Ryoung Kim
Young-Hwa Jean
O-Soo Lee
Publication date
01-12-2009
Publisher
BioMed Central
Published in
Virology Journal / Issue 1/2009
Electronic ISSN: 1743-422X
DOI
https://doi.org/10.1186/1743-422X-6-167

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