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Published in: Reproductive Health 1/2004

Open Access 01-12-2004 | Research

WHO systematic review of maternal morbidity and mortality: the prevalence of severe acute maternal morbidity (near miss)

Authors: Lale Say, Robert C Pattinson, A Metin Gülmezoglu

Published in: Reproductive Health | Issue 1/2004

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Abstract

Aim

To determine the prevalence of severe acute maternal morbidity (SAMM) worldwide (near miss).

Method

Systematic review of all available data. The methodology followed a pre-defined protocol, an extensive search strategy of 10 electronic databases as well as other sources. Articles were evaluated according to specified inclusion criteria. Data were extracted using data extraction instrument which collects additional information on the quality of reporting including definitions and identification of cases. Data were entered into a specially constructed database and tabulated using SAS statistical management and analysis software.

Results

A total of 30 studies are included in the systematic review. Designs are mainly cross-sectional and 24 were conducted in hospital settings, mostly teaching hospitals. Fourteen studies report on a defined SAMM condition while the remainder use a response to an event such as admission to intensive care unit as a proxy for SAMM. Criteria for identification of cases vary widely across studies. Prevalences vary between 0.80% – 8.23% in studies that use disease-specific criteria while the range is 0.38% – 1.09% in the group that use organ-system based criteria and included unselected group of women. Rates are within the range of 0.01% and 2.99% in studies using management-based criteria. It is not possible to pool data together to provide summary estimates or comparisons between different settings due to variations in case-identification criteria. Nevertheless, there seems to be an inverse trend in prevalence with development status of a country.

Conclusion

There is a clear need to set uniform criteria to classify patients as SAMM. This standardisation could be made for similar settings separately. An organ-system dysfunction/failure approach is the most epidemiologically sound as it is least open to bias, and thus could permit developing summary estimates.
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Literature
1.
go back to reference Mantel GD, Buchmann E, Rees H, Pattinson RC: Severe acute maternal morbidity: a pilot study of a definition for a near-miss. Br J Obstet Gynaecol. 1998, 105: 985-990.CrossRefPubMed Mantel GD, Buchmann E, Rees H, Pattinson RC: Severe acute maternal morbidity: a pilot study of a definition for a near-miss. Br J Obstet Gynaecol. 1998, 105: 985-990.CrossRefPubMed
2.
go back to reference Prual A, Bouvier-Colle M-H, De Bernis L, Bréart G: Severe maternal morbidity from direct obstetric causes in West Africa: incidence and case fatality rates. Bull World Health Organ. 2000, 78: 593-602.PubMedPubMedCentral Prual A, Bouvier-Colle M-H, De Bernis L, Bréart G: Severe maternal morbidity from direct obstetric causes in West Africa: incidence and case fatality rates. Bull World Health Organ. 2000, 78: 593-602.PubMedPubMedCentral
3.
go back to reference Stones W, Lim W, Al-Azzawi F, Kelly M: An investigation of maternal morbidity with identification of life-threatening 'near miss' episodes. Health Trends. 1991, 23: 13-15.PubMed Stones W, Lim W, Al-Azzawi F, Kelly M: An investigation of maternal morbidity with identification of life-threatening 'near miss' episodes. Health Trends. 1991, 23: 13-15.PubMed
4.
go back to reference Hall MH: Near misses and severe maternal morbidity. In Why mothers die 1997–1999: The confidential enquiries into maternal deaths in the United Kingdom. 2001, London: RCOG Press: Department of Health, Welsh Office, Scottish Home and Health Department, Department of Health and Social Sciences, Northern Ireland, 323-325. Hall MH: Near misses and severe maternal morbidity. In Why mothers die 1997–1999: The confidential enquiries into maternal deaths in the United Kingdom. 2001, London: RCOG Press: Department of Health, Welsh Office, Scottish Home and Health Department, Department of Health and Social Sciences, Northern Ireland, 323-325.
6.
go back to reference Gülmezoglu AM, Say L, Betran AP, Villar J, Piaggio G: WHO systematic review of maternal mortality and morbidity: methodological issues and challenges. BMC Med Res Methodol. 2004, 4: 16-10.1186/1471-2288-4-16.CrossRefPubMedPubMedCentral Gülmezoglu AM, Say L, Betran AP, Villar J, Piaggio G: WHO systematic review of maternal mortality and morbidity: methodological issues and challenges. BMC Med Res Methodol. 2004, 4: 16-10.1186/1471-2288-4-16.CrossRefPubMedPubMedCentral
7.
go back to reference Bouvier-Colle M-H, Varnoux N, Le groupe MOMS-B: Mortalité maternelle et morbidité grave dans trois régions françaises: resultats de MOMS, une enquête européenne multicentrique. J Gynecol Obstet Biol Reprod. 2001, 30: 2S5-2S9. Bouvier-Colle M-H, Varnoux N, Le groupe MOMS-B: Mortalité maternelle et morbidité grave dans trois régions françaises: resultats de MOMS, une enquête européenne multicentrique. J Gynecol Obstet Biol Reprod. 2001, 30: 2S5-2S9.
8.
go back to reference Brace V, Penney G, Hall M: Quantifying severe maternal morbidity: a Scottish population study. BJOG. 2004, 111: 481-484. 10.1111/j.1471-0528.2004.00101.x.CrossRefPubMed Brace V, Penney G, Hall M: Quantifying severe maternal morbidity: a Scottish population study. BJOG. 2004, 111: 481-484. 10.1111/j.1471-0528.2004.00101.x.CrossRefPubMed
9.
go back to reference Cochet L, Macdonald AP, Pattinson RC: Severe acute maternal morbidity and maternal death audit – a rapid diagnostic tool for evaluating maternal care. S Afr Med J. 2003, 93: 700-702.PubMed Cochet L, Macdonald AP, Pattinson RC: Severe acute maternal morbidity and maternal death audit – a rapid diagnostic tool for evaluating maternal care. S Afr Med J. 2003, 93: 700-702.PubMed
10.
go back to reference Filippi V, Alihonou E, Mukantaganda S, Graham WJ, Ronsmans C: Near misses: maternal morbidity and mortality. Lancet. 1998, 351: 145-146.CrossRefPubMed Filippi V, Alihonou E, Mukantaganda S, Graham WJ, Ronsmans C: Near misses: maternal morbidity and mortality. Lancet. 1998, 351: 145-146.CrossRefPubMed
11.
go back to reference Girard F, Burlet G, Bayoumeu F, Fresson J, Bouvier-Colle M-H, Boutroy J-L: Les complications sévères de la grossess et de l'accouchement: état des lieux en Lorraine dans le cadre de l'enquête européene. J Gynecol Obstet Biol Reprod. 2001, 30: 10-17. Girard F, Burlet G, Bayoumeu F, Fresson J, Bouvier-Colle M-H, Boutroy J-L: Les complications sévères de la grossess et de l'accouchement: état des lieux en Lorraine dans le cadre de l'enquête européene. J Gynecol Obstet Biol Reprod. 2001, 30: 10-17.
12.
go back to reference Kaye D, Mirembe F, Aziga F, Namulema B: Maternal mortality and associated near-misses among emergency intrapartum obstetric referrals in Mulago Hospital, Kampala, Uganda. East Afr Med J. 2003, 80: 144-149.PubMed Kaye D, Mirembe F, Aziga F, Namulema B: Maternal mortality and associated near-misses among emergency intrapartum obstetric referrals in Mulago Hospital, Kampala, Uganda. East Afr Med J. 2003, 80: 144-149.PubMed
13.
go back to reference Khosla AH, Dahiya K, Sangwan K: Maternal mortality and 'near-miss' in rural north India. Int J Gynecol Obstet. 2000, 68: 163-164. 10.1016/S0020-7292(99)00185-X.CrossRef Khosla AH, Dahiya K, Sangwan K: Maternal mortality and 'near-miss' in rural north India. Int J Gynecol Obstet. 2000, 68: 163-164. 10.1016/S0020-7292(99)00185-X.CrossRef
15.
go back to reference Prual A, Huguet D, Gabin O, Rabe G: Severe obstetric morbidity of the third trimester, delivery and early puerperium in Niamey (Niger). Afr J Reprod Health. 1998, 2: 10-19.PubMed Prual A, Huguet D, Gabin O, Rabe G: Severe obstetric morbidity of the third trimester, delivery and early puerperium in Niamey (Niger). Afr J Reprod Health. 1998, 2: 10-19.PubMed
16.
go back to reference Sahel A, De Brouwere V, Lardi M, Van Lerberghe W, Ronsmans C, Filippi V: Obstetric catastrophes barely just avoided: near misses in Moroccan hospitals. Sante. 2001, 11: 229-235.PubMed Sahel A, De Brouwere V, Lardi M, Van Lerberghe W, Ronsmans C, Filippi V: Obstetric catastrophes barely just avoided: near misses in Moroccan hospitals. Sante. 2001, 11: 229-235.PubMed
17.
go back to reference Sivalingam N, Looi K: Clinical experience with management of 'near-miss' cases in obstetrics. Med J Malaysia. 1999, 54: 496-503.PubMed Sivalingam N, Looi K: Clinical experience with management of 'near-miss' cases in obstetrics. Med J Malaysia. 1999, 54: 496-503.PubMed
18.
go back to reference Waterstone M, Bewley S, Wolfe C: Incidence and predictors of severe obstetric morbidity: case-control study. BMJ. 2001, 322: 1089-1094. 10.1136/bmj.322.7294.1089.CrossRefPubMedPubMedCentral Waterstone M, Bewley S, Wolfe C: Incidence and predictors of severe obstetric morbidity: case-control study. BMJ. 2001, 322: 1089-1094. 10.1136/bmj.322.7294.1089.CrossRefPubMedPubMedCentral
19.
go back to reference Baskett TF, Sternadel J: Maternal intensive care and near-miss mortality in obstetrics. Br J Obstet Gynaecol. 1998, 105: 981-984.CrossRefPubMed Baskett TF, Sternadel J: Maternal intensive care and near-miss mortality in obstetrics. Br J Obstet Gynaecol. 1998, 105: 981-984.CrossRefPubMed
20.
go back to reference Ben Letaifa D, Daouas N, Ben Jazia K, Slama A, Jegham H: Maternal emergencies requiring controlled ventilation: epidemiology and prognosis. J Gynecol Obstet Biol Reprod. 2002, 31: 256-260. Ben Letaifa D, Daouas N, Ben Jazia K, Slama A, Jegham H: Maternal emergencies requiring controlled ventilation: epidemiology and prognosis. J Gynecol Obstet Biol Reprod. 2002, 31: 256-260.
21.
go back to reference Bewley S, Creighton S: Near-miss obstetric enquiry. J Obstet Gynaecol (Paris). 1997, 17: 26-29.CrossRef Bewley S, Creighton S: Near-miss obstetric enquiry. J Obstet Gynaecol (Paris). 1997, 17: 26-29.CrossRef
22.
go back to reference Bouvier-Colle M-H, Ancel PY, Varnoux N, Salanave B, Fernandez H, Papiernik E, Bréart G: Soins intensifs des femmes en état gravido-puerpéral. Charactéristiques des patientes et structures de prise en charge. J Gynecol Obstet Biol Reprod. 1997, 26: 47-56. Bouvier-Colle M-H, Ancel PY, Varnoux N, Salanave B, Fernandez H, Papiernik E, Bréart G: Soins intensifs des femmes en état gravido-puerpéral. Charactéristiques des patientes et structures de prise en charge. J Gynecol Obstet Biol Reprod. 1997, 26: 47-56.
23.
go back to reference De Souza JPD, Duarte G, Basile-Filho A: Near-miss maternal mortality in devloping countries. Eur J Obstet Gynecol Reprod Biol. 2002, 104: 80-10.1016/S0301-2115(02)00206-3.CrossRef De Souza JPD, Duarte G, Basile-Filho A: Near-miss maternal mortality in devloping countries. Eur J Obstet Gynecol Reprod Biol. 2002, 104: 80-10.1016/S0301-2115(02)00206-3.CrossRef
24.
go back to reference Loverro G, Greco P, Vimercati A, Nicolardi V, Varcaccio-Garofalo G, Selvaggi L: Maternal complications associated with cesarean section. J Perinat Med. 2001, 29: 322-326.CrossRefPubMed Loverro G, Greco P, Vimercati A, Nicolardi V, Varcaccio-Garofalo G, Selvaggi L: Maternal complications associated with cesarean section. J Perinat Med. 2001, 29: 322-326.CrossRefPubMed
25.
go back to reference Murphy DJ, Charlett P: Cohort study of near-miss maternal mortality and subsequent reproductive outcome. Eur J Obstet Gynecol Reprod Biol. 2002, 102: 173-178. 10.1016/S0301-2115(01)00320-7.CrossRefPubMed Murphy DJ, Charlett P: Cohort study of near-miss maternal mortality and subsequent reproductive outcome. Eur J Obstet Gynecol Reprod Biol. 2002, 102: 173-178. 10.1016/S0301-2115(01)00320-7.CrossRefPubMed
26.
go back to reference Rodriguez-Iglesias G, Calzado JD, Riveiro LP: Experiencia de 12 años de trabajo la atención de adolescentes obstétricas criticamente enferma en la unidad de cuidados intensivos. Rev Cubana Obstet Ginecol. 1999, 25: 141-145. Rodriguez-Iglesias G, Calzado JD, Riveiro LP: Experiencia de 12 años de trabajo la atención de adolescentes obstétricas criticamente enferma en la unidad de cuidados intensivos. Rev Cubana Obstet Ginecol. 1999, 25: 141-145.
27.
go back to reference Ryan M, Hamilton V, Bowen M, McKenna P: The role of a high-dependency unit in a regional obstetric hospital. Anaesthesia. 2000, 55: 1155-1158. 10.1046/j.1365-2044.2000.01627.x.CrossRefPubMed Ryan M, Hamilton V, Bowen M, McKenna P: The role of a high-dependency unit in a regional obstetric hospital. Anaesthesia. 2000, 55: 1155-1158. 10.1046/j.1365-2044.2000.01627.x.CrossRefPubMed
28.
go back to reference Alsayali ARA, Baloul AMA: Emergency obstetric hysterectomy: 8-year review at Taif Maternity Hospital, Saudi Arabia. Ann Saudi Med. 2000, 20: 454-456.PubMed Alsayali ARA, Baloul AMA: Emergency obstetric hysterectomy: 8-year review at Taif Maternity Hospital, Saudi Arabia. Ann Saudi Med. 2000, 20: 454-456.PubMed
29.
go back to reference Bakshi S, Meyer BA: Indications for and outcomes of emergency peripartum hysterectomy. A five-year review. J Reprod Med. 2000, 45: 733-737.PubMed Bakshi S, Meyer BA: Indications for and outcomes of emergency peripartum hysterectomy. A five-year review. J Reprod Med. 2000, 45: 733-737.PubMed
30.
go back to reference Gould DA, Butler-Manuel AS, Turner MJ, Carter PG: Emergency obstetric hysterectomy-an increasing incidence. J Obstet Gynaecol. 1999, 19: 580-583. 10.1080/01443619963761.CrossRefPubMed Gould DA, Butler-Manuel AS, Turner MJ, Carter PG: Emergency obstetric hysterectomy-an increasing incidence. J Obstet Gynaecol. 1999, 19: 580-583. 10.1080/01443619963761.CrossRefPubMed
31.
32.
go back to reference Nasrat HA, Youssef MH, Marzoogi A, Talab F: 'Near miss' obstetric morbidity in an inner city hospital in Saudi Arabia. East Mediterr Health J. 1999, 5: 717-726.PubMed Nasrat HA, Youssef MH, Marzoogi A, Talab F: 'Near miss' obstetric morbidity in an inner city hospital in Saudi Arabia. East Mediterr Health J. 1999, 5: 717-726.PubMed
33.
go back to reference Noor S, Majid S, Ruby N: An audit of obstetrical hysterectomy. J Coll Physicians Surg Pak. 2001, 11: 642-645. Noor S, Majid S, Ruby N: An audit of obstetrical hysterectomy. J Coll Physicians Surg Pak. 2001, 11: 642-645.
34.
go back to reference Yamamoto H, Sagae S, Nishikawa S, Kudo R: Emergency postpartum hysterectomy in obstetric practice. J Obstet Gynaecol Res. 2000, 26: 341-345.CrossRefPubMed Yamamoto H, Sagae S, Nishikawa S, Kudo R: Emergency postpartum hysterectomy in obstetric practice. J Obstet Gynaecol Res. 2000, 26: 341-345.CrossRefPubMed
35.
go back to reference Pattinson RC, Hall MH: Near misses:a useful adjunct to maternal death enquiries. Br Med Bull. 2003, 67: 231-243. 10.1093/bmb/ldg007.CrossRefPubMed Pattinson RC, Hall MH: Near misses:a useful adjunct to maternal death enquiries. Br Med Bull. 2003, 67: 231-243. 10.1093/bmb/ldg007.CrossRefPubMed
36.
go back to reference Why mothers die 1997–1999. Report from the confidential enquiries into maternal deaths in the United Kingdom. 2000, London, National Statistics Office Why mothers die 1997–1999. Report from the confidential enquiries into maternal deaths in the United Kingdom. 2000, London, National Statistics Office
37.
go back to reference Vandecruys HI, Pattinson RC, Macdonald AP, Mantel GD: Severe acute maternal morbidity and mortality in the Pretoria Academic Complex: changing patterns over 4 years. Eur J Obstet Gynecol Reprod Biol. 2002, 102: 6-10. 10.1016/S0301-2115(01)00558-9.CrossRefPubMed Vandecruys HI, Pattinson RC, Macdonald AP, Mantel GD: Severe acute maternal morbidity and mortality in the Pretoria Academic Complex: changing patterns over 4 years. Eur J Obstet Gynecol Reprod Biol. 2002, 102: 6-10. 10.1016/S0301-2115(01)00558-9.CrossRefPubMed
Metadata
Title
WHO systematic review of maternal morbidity and mortality: the prevalence of severe acute maternal morbidity (near miss)
Authors
Lale Say
Robert C Pattinson
A Metin Gülmezoglu
Publication date
01-12-2004
Publisher
BioMed Central
Published in
Reproductive Health / Issue 1/2004
Electronic ISSN: 1742-4755
DOI
https://doi.org/10.1186/1742-4755-1-3

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