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Reproductive Health
Published in: Reproductive Health 1/2004

Open Access 01-12-2004 | Review

Genomic imprinting and assisted reproduction

Authors: Ariane Paoloni-Giacobino, J Richard Chaillet

Published in: Reproductive Health | Issue 1/2004

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Abstract

Imprinted genes exhibit a parent-of-origin specific pattern of expression. Such genes have been shown to be targets of molecular defects in particular genetic syndromes such as Beckwith-Wiedemann and Angelman syndromes. Recent reports have raised concern about the possibility that assisted reproduction techniques, such as in vitro fertilization or intracytoplasmic sperm injection, might cause genomic imprinting disorders. The number of reported cases of those disorders is still too small to draw firm conclusions and the safety of these widely used assisted reproduction techniques needs to be further evaluated.
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Metadata
Title
Genomic imprinting and assisted reproduction
Authors
Ariane Paoloni-Giacobino
J Richard Chaillet
Publication date
01-12-2004
Publisher
BioMed Central
Published in
Reproductive Health / Issue 1/2004
Electronic ISSN: 1742-4755
DOI
https://doi.org/10.1186/1742-4755-1-6

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