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Published in: BMC Medicine 1/2014

Open Access 01-12-2014 | Review

Early life programming as a target for prevention of child and adolescent mental disorders

Authors: Andrew James Lewis, Megan Galbally, Tara Gannon, Christos Symeonides

Published in: BMC Medicine | Issue 1/2014

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Abstract

This paper concerns future policy development and programs of research for the prevention of mental disorders based on research emerging from fetal and early life programming. The current review offers an overview of findings on pregnancy exposures such as maternal mental health, lifestyle factors, and potential teratogenic and neurotoxic exposures on child outcomes. Outcomes of interest are common child and adolescent mental disorders including hyperactive, behavioral and emotional disorders. This literature suggests that the preconception and perinatal periods offer important opportunities for the prevention of deleterious fetal exposures. As such, the perinatal period is a critical period where future mental health prevention efforts should be focused and prevention models developed. Interventions grounded in evidence-based recommendations for the perinatal period could take the form of public health, universal and more targeted interventions. If successful, such interventions are likely to have lifelong effects on (mental) health.
Literature
1.
go back to reference Barker DJ: The developmental origins of chronic adult disease. Acta Paediatrica. 2004, 93: 26-33.PubMed Barker DJ: The developmental origins of chronic adult disease. Acta Paediatrica. 2004, 93: 26-33.PubMed
2.
go back to reference Belfer ML: Child and adolescent mental disorders: the magnitude of the problem across the globe. J Child Psychol Psychiatry. 2008, 49: 226-236. 10.1111/j.1469-7610.2007.01855.x.PubMed Belfer ML: Child and adolescent mental disorders: the magnitude of the problem across the globe. J Child Psychol Psychiatry. 2008, 49: 226-236. 10.1111/j.1469-7610.2007.01855.x.PubMed
3.
go back to reference Ravens-Sieberer U, Wille N, Erhart M, Bettge S, Wittchen HU, Rothenberger A, Herpertz-Dahlmann B, Resch F, Holling H, Bullinger M, Barkmann C, Schulte-Markwort M, Dopfner M, BELLA study group: Prevalence of mental health problems among children and adolescents in Germany: results of the BELLA study within the National Health Interview and Examination Survey. Eur Child Adolesc Psychiatry. 2008, 17: 22-33. 10.1007/s00787-008-1003-2.PubMed Ravens-Sieberer U, Wille N, Erhart M, Bettge S, Wittchen HU, Rothenberger A, Herpertz-Dahlmann B, Resch F, Holling H, Bullinger M, Barkmann C, Schulte-Markwort M, Dopfner M, BELLA study group: Prevalence of mental health problems among children and adolescents in Germany: results of the BELLA study within the National Health Interview and Examination Survey. Eur Child Adolesc Psychiatry. 2008, 17: 22-33. 10.1007/s00787-008-1003-2.PubMed
4.
go back to reference Sawyer MG, Arney FM, Baghurst PA, Clarke JJ, Graetz BW, Kosky RJ, Nurcomber B, Patton GC, Prior MR, Raphael B, et al: The mental health of young people in Australia-key findings from the child and adolescent component of the national survey of mental health and well-being. Aust N Z J Psychiatry. 2001, 35: 806-814. 10.1046/j.1440-1614.2001.00964.x.PubMed Sawyer MG, Arney FM, Baghurst PA, Clarke JJ, Graetz BW, Kosky RJ, Nurcomber B, Patton GC, Prior MR, Raphael B, et al: The mental health of young people in Australia-key findings from the child and adolescent component of the national survey of mental health and well-being. Aust N Z J Psychiatry. 2001, 35: 806-814. 10.1046/j.1440-1614.2001.00964.x.PubMed
5.
go back to reference Merikangas KR, He JP, Brody D, Fisher PW, Bourdon K, Koretz DS: Prevalence and treatment of mental disorders among US children in the 2001–2004 NHANES. Pediatrics. 2010, 125: 75-81. 10.1542/peds.2008-2598.PubMed Merikangas KR, He JP, Brody D, Fisher PW, Bourdon K, Koretz DS: Prevalence and treatment of mental disorders among US children in the 2001–2004 NHANES. Pediatrics. 2010, 125: 75-81. 10.1542/peds.2008-2598.PubMed
6.
go back to reference Meltzer H: Childhood mental disorders in Great Britain: an epidemiological perspective. Child Care Pract. 2007, 13: 313-326. 10.1080/13575270701488683. Meltzer H: Childhood mental disorders in Great Britain: an epidemiological perspective. Child Care Pract. 2007, 13: 313-326. 10.1080/13575270701488683.
7.
go back to reference Rescorla L, Achenbach TM, Ivanova MY, Dumenci L, Almqvist F, Bilenberg N, Bird H, Broberg A, Dobrean A, Dopfner M, et al: Epidemiological comparisons of problems and positive qualities reported by adolescents in 24 countries. J Consult Clin Psychol. 2007, 75: 351-358.PubMed Rescorla L, Achenbach TM, Ivanova MY, Dumenci L, Almqvist F, Bilenberg N, Bird H, Broberg A, Dobrean A, Dopfner M, et al: Epidemiological comparisons of problems and positive qualities reported by adolescents in 24 countries. J Consult Clin Psychol. 2007, 75: 351-358.PubMed
8.
go back to reference Angold A, Costello EJ, Worthman CM: Puberty and depression- the roles of age, pubertal status and pubertal timing. Psychol Med. 1998, 28: 51-61. 10.1017/S003329179700593X.PubMed Angold A, Costello EJ, Worthman CM: Puberty and depression- the roles of age, pubertal status and pubertal timing. Psychol Med. 1998, 28: 51-61. 10.1017/S003329179700593X.PubMed
9.
go back to reference Mueller BR, Bale TL: Sex-specific programming of offspring emotionality after stress early in pregnancy. J Neurosci. 2008, 28: 9055-9065. 10.1523/JNEUROSCI.1424-08.2008.PubMedPubMedCentral Mueller BR, Bale TL: Sex-specific programming of offspring emotionality after stress early in pregnancy. J Neurosci. 2008, 28: 9055-9065. 10.1523/JNEUROSCI.1424-08.2008.PubMedPubMedCentral
10.
go back to reference Barker DJ: The Wellcome Foundation Lecture, 1994. The fetal origins of adult disease. Proc Biol Sci. 1995, 262: 37-43. 10.1098/rspb.1995.0173.PubMed Barker DJ: The Wellcome Foundation Lecture, 1994. The fetal origins of adult disease. Proc Biol Sci. 1995, 262: 37-43. 10.1098/rspb.1995.0173.PubMed
11.
go back to reference Gluckman PD, Hanson MA: The developmental origins of health and disease: the breadth and importance of the concept. Early Life Origins of Health and Disease. Edited by: Wintour EM, Owens JA. 2006, New York, NY: Springer Science + Business Media Gluckman PD, Hanson MA: The developmental origins of health and disease: the breadth and importance of the concept. Early Life Origins of Health and Disease. Edited by: Wintour EM, Owens JA. 2006, New York, NY: Springer Science + Business Media
12.
go back to reference Kieling C, Baker-Henningham H, Belfer M, Conti G, Ertem I, Omigbodun O, Rohde LA, Srinath S, Ulkuer N, Rahman A: Child and adolescent mental health worldwide: evidence for action. Lancet. 2011, 378: 1515-1525. 10.1016/S0140-6736(11)60827-1.PubMed Kieling C, Baker-Henningham H, Belfer M, Conti G, Ertem I, Omigbodun O, Rohde LA, Srinath S, Ulkuer N, Rahman A: Child and adolescent mental health worldwide: evidence for action. Lancet. 2011, 378: 1515-1525. 10.1016/S0140-6736(11)60827-1.PubMed
13.
go back to reference Stearns SC, Koella JC: The evolution of phenotypic plasticity in life-history traits: predictions of reaction norms for age and size at maturity. Evolution. 1986, 40: 893-913. 10.2307/2408752. Stearns SC, Koella JC: The evolution of phenotypic plasticity in life-history traits: predictions of reaction norms for age and size at maturity. Evolution. 1986, 40: 893-913. 10.2307/2408752.
14.
go back to reference Gluckman PD, Hanson MA, Beedle AS: Early life events and their consequences for later disease: a life history and evolutionary perspective. Am J Hum Biol. 2007, 19: 1-19. 10.1002/ajhb.20590.PubMed Gluckman PD, Hanson MA, Beedle AS: Early life events and their consequences for later disease: a life history and evolutionary perspective. Am J Hum Biol. 2007, 19: 1-19. 10.1002/ajhb.20590.PubMed
15.
go back to reference West-Eberhard MJ: Developmental Plasticity and Evolution. 2003, Oxford: Oxford University Press West-Eberhard MJ: Developmental Plasticity and Evolution. 2003, Oxford: Oxford University Press
16.
go back to reference Gluckman PD, Hanson MA, Bateson P, Beedle AS, Law CM, Bhutta ZA, Anokhin KV, Bougnères P, Chandak GR, Dasgupta P, et al: Towards a new developmental synthesis: adaptive developmental plasticity and human disease. Lancet. 2009, 373: 1654-1657. 10.1016/S0140-6736(09)60234-8.PubMed Gluckman PD, Hanson MA, Bateson P, Beedle AS, Law CM, Bhutta ZA, Anokhin KV, Bougnères P, Chandak GR, Dasgupta P, et al: Towards a new developmental synthesis: adaptive developmental plasticity and human disease. Lancet. 2009, 373: 1654-1657. 10.1016/S0140-6736(09)60234-8.PubMed
17.
go back to reference Bateson P, Barker D, Clutton-Brock T, Deb D, D'Udine B, Foley R, Gluckman P, Godfrey K, Kirkwood T, Lahr M: Developmental plasticity and human health. Nature. 2004, 430: 419-421. 10.1038/nature02725.PubMed Bateson P, Barker D, Clutton-Brock T, Deb D, D'Udine B, Foley R, Gluckman P, Godfrey K, Kirkwood T, Lahr M: Developmental plasticity and human health. Nature. 2004, 430: 419-421. 10.1038/nature02725.PubMed
18.
go back to reference Gluckman PD, Hanson MA: The conceptual basis for the developmental origins of health and disease. Developmental Origins of Health and Disease. Edited by: Gluckman PD, Hanson MA. 2006, New York: Cambridge University Press, 33-50. Gluckman PD, Hanson MA: The conceptual basis for the developmental origins of health and disease. Developmental Origins of Health and Disease. Edited by: Gluckman PD, Hanson MA. 2006, New York: Cambridge University Press, 33-50.
19.
go back to reference Ollikainen M, Smith KR, Joo EJ-H, Ng HK, Andronikos R, Novakovic B, Aziz NKA, Carlin JB, Morley R, Saffery R: DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome. Hum Mol Genet. 2010, 19: 4176-4188. 10.1093/hmg/ddq336.PubMed Ollikainen M, Smith KR, Joo EJ-H, Ng HK, Andronikos R, Novakovic B, Aziz NKA, Carlin JB, Morley R, Saffery R: DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome. Hum Mol Genet. 2010, 19: 4176-4188. 10.1093/hmg/ddq336.PubMed
20.
go back to reference Meaney MJ, Szyf M, Seckl JR: Epigenetic mechanisms of perinatal programming of hypothalamic-pituitary-adrenal function and health. Trends Mol Med. 2007, 13: 269-277. 10.1016/j.molmed.2007.05.003.PubMed Meaney MJ, Szyf M, Seckl JR: Epigenetic mechanisms of perinatal programming of hypothalamic-pituitary-adrenal function and health. Trends Mol Med. 2007, 13: 269-277. 10.1016/j.molmed.2007.05.003.PubMed
21.
go back to reference Schlotz W, Phillips DI: Fetal origins of mental health: evidence and mechanisms. Brain Behav Immun. 2009, 23: 905-916. 10.1016/j.bbi.2009.02.001.PubMed Schlotz W, Phillips DI: Fetal origins of mental health: evidence and mechanisms. Brain Behav Immun. 2009, 23: 905-916. 10.1016/j.bbi.2009.02.001.PubMed
22.
go back to reference Whitelaw E, Garrick D: Epigenetic mechanisms. Developmental Origins of Health and Disease. Edited by: Gluckman PD, Hanson MA. 2006, New York: Cambridge University Press, 62-74. Whitelaw E, Garrick D: Epigenetic mechanisms. Developmental Origins of Health and Disease. Edited by: Gluckman PD, Hanson MA. 2006, New York: Cambridge University Press, 62-74.
23.
go back to reference Martino D, Loke YJ, Gordon L, Ollikainen M, Cruickshank MN, Saffery R, Craig JM: Longitudinal, genome-scale analysis of DNA methylation in twins from birth to 18 months of age reveals rapid epigenetic change in early life and pair-specific effects of discordance. Genome Biol. 2013, 14: R42-10.1186/gb-2013-14-5-r42.PubMedPubMedCentral Martino D, Loke YJ, Gordon L, Ollikainen M, Cruickshank MN, Saffery R, Craig JM: Longitudinal, genome-scale analysis of DNA methylation in twins from birth to 18 months of age reveals rapid epigenetic change in early life and pair-specific effects of discordance. Genome Biol. 2013, 14: R42-10.1186/gb-2013-14-5-r42.PubMedPubMedCentral
24.
go back to reference Barker DJ, Osmond C, Rodin I, Fall C, Winter P: Low weight gain in infancy and suicide in adult life. BMJ. 1995, 311: 1203-10.1136/bmj.311.7014.1203.PubMedPubMedCentral Barker DJ, Osmond C, Rodin I, Fall C, Winter P: Low weight gain in infancy and suicide in adult life. BMJ. 1995, 311: 1203-10.1136/bmj.311.7014.1203.PubMedPubMedCentral
25.
go back to reference Talge NM, Neal C, Glover V: Antenatal maternal stress and long-term effects on child neurodevelopment: how and why?. J Child Psychol Psychiatry. 2007, 48: 245-261. 10.1111/j.1469-7610.2006.01714.x.PubMed Talge NM, Neal C, Glover V: Antenatal maternal stress and long-term effects on child neurodevelopment: how and why?. J Child Psychol Psychiatry. 2007, 48: 245-261. 10.1111/j.1469-7610.2006.01714.x.PubMed
26.
go back to reference Swanson JD, Wadhwa PM: Developmental origins of child mental health disorders. J Child Psychol Psychiatry. 2008, 49: 1009-1019. 10.1111/j.1469-7610.2008.02014.x.PubMedPubMedCentral Swanson JD, Wadhwa PM: Developmental origins of child mental health disorders. J Child Psychol Psychiatry. 2008, 49: 1009-1019. 10.1111/j.1469-7610.2008.02014.x.PubMedPubMedCentral
27.
go back to reference Lupien SJ, McEwen BS, Gunnar MR, Heim C: Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nat Rev Neurosci. 2009, 10: 434-445. 10.1038/nrn2639.PubMed Lupien SJ, McEwen BS, Gunnar MR, Heim C: Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nat Rev Neurosci. 2009, 10: 434-445. 10.1038/nrn2639.PubMed
28.
go back to reference Bolt R, Van Weissenbruch M, Lafeber H, Delemarre-Van de Waal H: Development of the hypothalamic-pituitary-adrenal axis in the fetus and preterm infant. J Pediatr Endocrinol Metab. 2002, 15: 759-770.PubMed Bolt R, Van Weissenbruch M, Lafeber H, Delemarre-Van de Waal H: Development of the hypothalamic-pituitary-adrenal axis in the fetus and preterm infant. J Pediatr Endocrinol Metab. 2002, 15: 759-770.PubMed
29.
go back to reference Challis J, Sloboda D, Matthews S, Holloway A, Alfaidy N, Patel F, Whittle W, Fraser M, Moss T, Newnham J: The fetal placental hypothalamic–pituitary–adrenal (HPA) axis, parturition and post natal health. Mol Cell Endocrinol. 2001, 185: 135-144. 10.1016/S0303-7207(01)00624-4.PubMed Challis J, Sloboda D, Matthews S, Holloway A, Alfaidy N, Patel F, Whittle W, Fraser M, Moss T, Newnham J: The fetal placental hypothalamic–pituitary–adrenal (HPA) axis, parturition and post natal health. Mol Cell Endocrinol. 2001, 185: 135-144. 10.1016/S0303-7207(01)00624-4.PubMed
30.
go back to reference De Kloet ER, Joëls M, Holsboer F: Stress and the brain: from adaptation to disease. Nat Rev Neurosci. 2005, 6: 463-475. 10.1038/nrn1683.PubMed De Kloet ER, Joëls M, Holsboer F: Stress and the brain: from adaptation to disease. Nat Rev Neurosci. 2005, 6: 463-475. 10.1038/nrn1683.PubMed
31.
go back to reference Phillips DI, Jones A: Fetal programming of autonomic and HPA function: do people who were small babies have enhanced stress responses?. J Physiol. 2006, 572: 45-50.PubMedPubMedCentral Phillips DI, Jones A: Fetal programming of autonomic and HPA function: do people who were small babies have enhanced stress responses?. J Physiol. 2006, 572: 45-50.PubMedPubMedCentral
32.
go back to reference Price D, Close G, Fielding B: Age of appearance of circadian rhythm in salivary cortisol values in infancy. Arch Dis Child. 1983, 58: 454-456. 10.1136/adc.58.6.454.PubMedPubMedCentral Price D, Close G, Fielding B: Age of appearance of circadian rhythm in salivary cortisol values in infancy. Arch Dis Child. 1983, 58: 454-456. 10.1136/adc.58.6.454.PubMedPubMedCentral
33.
go back to reference Gunnar M, Quevedo K: The neurobiology of stress and development. Annu Rev Psychol. 2007, 58: 145-173. 10.1146/annurev.psych.58.110405.085605.PubMed Gunnar M, Quevedo K: The neurobiology of stress and development. Annu Rev Psychol. 2007, 58: 145-173. 10.1146/annurev.psych.58.110405.085605.PubMed
34.
go back to reference Cottrell EC, Seckl JR: Prenatal stress, glucocorticoids and the programming of adult disease. Front Behav Neurosci. 2009, 3: 1-9. Cottrell EC, Seckl JR: Prenatal stress, glucocorticoids and the programming of adult disease. Front Behav Neurosci. 2009, 3: 1-9.
35.
go back to reference O'donnell K, O'connor T, Glover V: Prenatal stress and neurodevelopment of the child: focus on the HPA axis and role of the placenta. Dev Neurosci. 2009, 31: 285-292. 10.1159/000216539.PubMed O'donnell K, O'connor T, Glover V: Prenatal stress and neurodevelopment of the child: focus on the HPA axis and role of the placenta. Dev Neurosci. 2009, 31: 285-292. 10.1159/000216539.PubMed
36.
go back to reference Monk C, Spicer J, Champagne FA: Linking prenatal maternal adversity to developmental outcomes in infants: the role of epigenetic pathways. Dev Psychopathol. 2012, 24: 1361-1376. 10.1017/S0954579412000764.PubMedPubMedCentral Monk C, Spicer J, Champagne FA: Linking prenatal maternal adversity to developmental outcomes in infants: the role of epigenetic pathways. Dev Psychopathol. 2012, 24: 1361-1376. 10.1017/S0954579412000764.PubMedPubMedCentral
37.
go back to reference Schroeder JW, Smith AK, Brennan PA, Conneely KN, Kilaru V, Knight BT, Newport DJ, Cubells JF, Stowe ZN: DNA methylation in neonates born to women receiving psychiatric care. Epigenetics. 2012, 7: 409-414. 10.4161/epi.19551.PubMedPubMedCentral Schroeder JW, Smith AK, Brennan PA, Conneely KN, Kilaru V, Knight BT, Newport DJ, Cubells JF, Stowe ZN: DNA methylation in neonates born to women receiving psychiatric care. Epigenetics. 2012, 7: 409-414. 10.4161/epi.19551.PubMedPubMedCentral
38.
go back to reference Smith AK, Conneely KN, Newport DJ, Kilaru V, Schroeder JW, Pennell PB, Knight BT, Cubells JC, Stowe ZN, Brennan PA: Prenatal antiepileptic exposure associates with neonatal DNA methylation differences. Epigenetics. 2012, 7: 458-463. 10.4161/epi.19617.PubMedPubMedCentral Smith AK, Conneely KN, Newport DJ, Kilaru V, Schroeder JW, Pennell PB, Knight BT, Cubells JC, Stowe ZN, Brennan PA: Prenatal antiepileptic exposure associates with neonatal DNA methylation differences. Epigenetics. 2012, 7: 458-463. 10.4161/epi.19617.PubMedPubMedCentral
39.
go back to reference Oberlander TF, Weinberg J, Papsdorf M, Grunau R, Misri S, Devlin AM: Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses. Epigenetics. 2008, 3: 97-106. 10.4161/epi.3.2.6034.PubMed Oberlander TF, Weinberg J, Papsdorf M, Grunau R, Misri S, Devlin AM: Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses. Epigenetics. 2008, 3: 97-106. 10.4161/epi.3.2.6034.PubMed
40.
go back to reference Nathanielsz PW, Nathanielsz P: Life in the Womb: The Origin of Health and Disease. 1999, Ithaca, NY: Promethean Press Nathanielsz PW, Nathanielsz P: Life in the Womb: The Origin of Health and Disease. 1999, Ithaca, NY: Promethean Press
41.
go back to reference Barker DJ: Maternal nutrition, fetal nutrition, and disease in later life. Nutrition. 1997, 13: 807-813. 10.1016/S0899-9007(97)00193-7.PubMed Barker DJ: Maternal nutrition, fetal nutrition, and disease in later life. Nutrition. 1997, 13: 807-813. 10.1016/S0899-9007(97)00193-7.PubMed
42.
go back to reference Bale TL, Baram TZ, Brown AS, Goldstein JM, Insel TR, McCarthy MM, Nemeroff CB, Reyes TM, Simerly RB, Susser ES: Early life programming and neurodevelopmental disorders. Biol Psychiatry. 2010, 68: 314-319. 10.1016/j.biopsych.2010.05.028.PubMedPubMedCentral Bale TL, Baram TZ, Brown AS, Goldstein JM, Insel TR, McCarthy MM, Nemeroff CB, Reyes TM, Simerly RB, Susser ES: Early life programming and neurodevelopmental disorders. Biol Psychiatry. 2010, 68: 314-319. 10.1016/j.biopsych.2010.05.028.PubMedPubMedCentral
43.
go back to reference Sullivan EL, Grayson B, Takahashi D, Robertson N, Maier A, Bethea CL, Smith MS, Coleman K, Grove KL: Chronic consumption of a high-fat diet during pregnancy causes perturbations in the serotonergic system and increased anxiety-like behavior in nonhuman primate offspring. J Neurosci. 2010, 30: 3826-3830. 10.1523/JNEUROSCI.5560-09.2010.PubMedPubMedCentral Sullivan EL, Grayson B, Takahashi D, Robertson N, Maier A, Bethea CL, Smith MS, Coleman K, Grove KL: Chronic consumption of a high-fat diet during pregnancy causes perturbations in the serotonergic system and increased anxiety-like behavior in nonhuman primate offspring. J Neurosci. 2010, 30: 3826-3830. 10.1523/JNEUROSCI.5560-09.2010.PubMedPubMedCentral
44.
go back to reference Vucetic Z, Kimmel J, Totoki K, Hollenbeck E, Reyes TM: Maternal high-fat diet alters methylation and gene expression of dopamine and opioid-related genes. Endocrinology. 2010, 151: 4756-4764. 10.1210/en.2010-0505.PubMedPubMedCentral Vucetic Z, Kimmel J, Totoki K, Hollenbeck E, Reyes TM: Maternal high-fat diet alters methylation and gene expression of dopamine and opioid-related genes. Endocrinology. 2010, 151: 4756-4764. 10.1210/en.2010-0505.PubMedPubMedCentral
45.
go back to reference Jacka FN, Ystrom E, Brantsaeter AL, Karevold E, Roth C, Haugen M, Meltzer HM, Schjolberg S, Berk M: Maternal and early postnatal nutrition and mental health of offspring by age 5 years: a prospective cohort study. J Am Acad Child Adolesc Psychiatr. 2013, 52: 1038-1047. 10.1016/j.jaac.2013.07.002. Jacka FN, Ystrom E, Brantsaeter AL, Karevold E, Roth C, Haugen M, Meltzer HM, Schjolberg S, Berk M: Maternal and early postnatal nutrition and mental health of offspring by age 5 years: a prospective cohort study. J Am Acad Child Adolesc Psychiatr. 2013, 52: 1038-1047. 10.1016/j.jaac.2013.07.002.
46.
go back to reference Keenan K, Bartlett TQ, Nijland M, Rodriguez JS, Nathanielsz PW, Zürcher NR: Poor nutrition during pregnancy and lactation negatively affects neurodevelopment of the offspring: evidence from a translational primate model. Am J Clin Nutr. 2013, 98: 396-402. 10.3945/ajcn.112.040352.PubMedPubMedCentral Keenan K, Bartlett TQ, Nijland M, Rodriguez JS, Nathanielsz PW, Zürcher NR: Poor nutrition during pregnancy and lactation negatively affects neurodevelopment of the offspring: evidence from a translational primate model. Am J Clin Nutr. 2013, 98: 396-402. 10.3945/ajcn.112.040352.PubMedPubMedCentral
47.
go back to reference Rodriguez A: Maternal pre‒pregnancy obesity and risk for inattention and negative emotionality in children. J Child Psychol Psychiatry. 2010, 51: 134-143. 10.1111/j.1469-7610.2009.02133.x.PubMed Rodriguez A: Maternal pre‒pregnancy obesity and risk for inattention and negative emotionality in children. J Child Psychol Psychiatry. 2010, 51: 134-143. 10.1111/j.1469-7610.2009.02133.x.PubMed
48.
go back to reference Van Lieshout RJ, Taylor VH, Boyle MH: Pre-pregnancy and pregnancy obesity and neurodevelopmental outcomes in offspring: a systematic review. Obes Rev. 2011, 12: e548-e559. 10.1111/j.1467-789X.2010.00850.x.PubMed Van Lieshout RJ, Taylor VH, Boyle MH: Pre-pregnancy and pregnancy obesity and neurodevelopmental outcomes in offspring: a systematic review. Obes Rev. 2011, 12: e548-e559. 10.1111/j.1467-789X.2010.00850.x.PubMed
49.
go back to reference Goodman SH, Gotlib IH: Risk for psychopathology in the children of depressed mothers: a developmental model for understanding mechanisms of transmission. Psychol Rev. 1999, 106: 458-490.PubMed Goodman SH, Gotlib IH: Risk for psychopathology in the children of depressed mothers: a developmental model for understanding mechanisms of transmission. Psychol Rev. 1999, 106: 458-490.PubMed
50.
go back to reference Grote NK, Bridge JA, Gavin AR, Melville JL, Iyengar S, Katon WJ: A meta-analysis of depression during pregnancy and the risk of preterm birth, low birth weight, and intrauterine growth restriction. Arch Gen Psychiatry. 2010, 67: 1012-10.1001/archgenpsychiatry.2010.111.PubMedPubMedCentral Grote NK, Bridge JA, Gavin AR, Melville JL, Iyengar S, Katon WJ: A meta-analysis of depression during pregnancy and the risk of preterm birth, low birth weight, and intrauterine growth restriction. Arch Gen Psychiatry. 2010, 67: 1012-10.1001/archgenpsychiatry.2010.111.PubMedPubMedCentral
51.
go back to reference Murray L, Halligan SL, Goodyer I, Herbert J: Disturbances in early parenting of depressed mothers and cortisol secretion in offspring: a preliminary study. J Affect Disord. 2010, 122: 218-223. 10.1016/j.jad.2009.06.034.PubMed Murray L, Halligan SL, Goodyer I, Herbert J: Disturbances in early parenting of depressed mothers and cortisol secretion in offspring: a preliminary study. J Affect Disord. 2010, 122: 218-223. 10.1016/j.jad.2009.06.034.PubMed
52.
go back to reference Bagner DM, Pettit JW, Lewinsohn PM, Seeley JR: Effect of maternal depression on child behavior: a sensitive period?. J Am Acad Child Adolesc Psychiatry. 2010, 49: 699-707.PubMedPubMedCentral Bagner DM, Pettit JW, Lewinsohn PM, Seeley JR: Effect of maternal depression on child behavior: a sensitive period?. J Am Acad Child Adolesc Psychiatry. 2010, 49: 699-707.PubMedPubMedCentral
53.
go back to reference Bureau JF, Easterbrooks MA, Lyons-Ruth K: Maternal depressive symptoms in infancy: unique contribution to children's depressive symptoms in childhood and adolescence?. Dev Psychopathol. 2009, 21: 519-537. 10.1017/S0954579409000285.PubMedPubMedCentral Bureau JF, Easterbrooks MA, Lyons-Ruth K: Maternal depressive symptoms in infancy: unique contribution to children's depressive symptoms in childhood and adolescence?. Dev Psychopathol. 2009, 21: 519-537. 10.1017/S0954579409000285.PubMedPubMedCentral
54.
go back to reference Dawson G, Klinger LG, Panagiotides H, Hill D, Spieker S: Frontal lobe activity and affective behavior of infants of mothers with depressive symptoms. Child Dev. 1992, 63: 725-737. 10.2307/1131357.PubMed Dawson G, Klinger LG, Panagiotides H, Hill D, Spieker S: Frontal lobe activity and affective behavior of infants of mothers with depressive symptoms. Child Dev. 1992, 63: 725-737. 10.2307/1131357.PubMed
55.
go back to reference Tronick EZ: Emotions and emotional communication in infants. Am Psychol. 1989, 44: 112-119.PubMed Tronick EZ: Emotions and emotional communication in infants. Am Psychol. 1989, 44: 112-119.PubMed
56.
go back to reference Field T: Maternal depression effects on infants and early interventions. Prev Med. 1998, 27: 200-203. 10.1006/pmed.1998.0293.PubMed Field T: Maternal depression effects on infants and early interventions. Prev Med. 1998, 27: 200-203. 10.1006/pmed.1998.0293.PubMed
57.
go back to reference Gotlib IH, Whiffen VE, Mount JH, Milne K, Cordy NI: Prevalence rates and demographic characteristics associated with depression in pregnancy and the postpartum. J Consult Clin Psychol. 1989, 57: 269-274.PubMed Gotlib IH, Whiffen VE, Mount JH, Milne K, Cordy NI: Prevalence rates and demographic characteristics associated with depression in pregnancy and the postpartum. J Consult Clin Psychol. 1989, 57: 269-274.PubMed
58.
go back to reference O'Hara MW, Swain AM: Rates and risk of postpartum degression - a meta-analysis. Int Rev Psychiatry. 1996, 8: 37-54. 10.3109/09540269609037816. O'Hara MW, Swain AM: Rates and risk of postpartum degression - a meta-analysis. Int Rev Psychiatry. 1996, 8: 37-54. 10.3109/09540269609037816.
59.
go back to reference Martins C, Gaffan EA: Effects of early maternal depression on patterns of infant-mother attachment: a meta-analytic investigation. J Child Psychol Psychiatry. 2000, 41: 737-746. 10.1111/1469-7610.00661.PubMed Martins C, Gaffan EA: Effects of early maternal depression on patterns of infant-mother attachment: a meta-analytic investigation. J Child Psychol Psychiatry. 2000, 41: 737-746. 10.1111/1469-7610.00661.PubMed
60.
go back to reference Weinstock M: The potential influence of maternal stress hormones on development and mental health of the offspring. Brain Behav Immun. 2005, 19: 296-308. 10.1016/j.bbi.2004.09.006.PubMed Weinstock M: The potential influence of maternal stress hormones on development and mental health of the offspring. Brain Behav Immun. 2005, 19: 296-308. 10.1016/j.bbi.2004.09.006.PubMed
61.
go back to reference Van den Bergh BRH, Marcoen A: High antenatal maternal anxiety is related to ADHD symptoms, externalizing problems, and anxiety in 8- and 9-year-olds. Child Dev. 2004, 75: 1085-1097. 10.1111/j.1467-8624.2004.00727.x.PubMed Van den Bergh BRH, Marcoen A: High antenatal maternal anxiety is related to ADHD symptoms, externalizing problems, and anxiety in 8- and 9-year-olds. Child Dev. 2004, 75: 1085-1097. 10.1111/j.1467-8624.2004.00727.x.PubMed
62.
go back to reference Bergman K, Sarkar P, Glover V, O'Connor TG: Maternal prenatal cortisol and infant cognitive development: moderation by infant-mother attachment. Biol Psychiatry. 2010, 67: 1026-1032. 10.1016/j.biopsych.2010.01.002.PubMedPubMedCentral Bergman K, Sarkar P, Glover V, O'Connor TG: Maternal prenatal cortisol and infant cognitive development: moderation by infant-mother attachment. Biol Psychiatry. 2010, 67: 1026-1032. 10.1016/j.biopsych.2010.01.002.PubMedPubMedCentral
63.
go back to reference Lewis AJ, Olsson CA: Early life stress and child temperament style as predictors of childhood anxiety and depressive symptoms: findings from the longitudinal study of Australian children. Depress Res Treat. 2011, 2012: 1-9. Lewis AJ, Olsson CA: Early life stress and child temperament style as predictors of childhood anxiety and depressive symptoms: findings from the longitudinal study of Australian children. Depress Res Treat. 2011, 2012: 1-9.
64.
go back to reference Kaplan LA, Evans L, Monk C: Effects of mothers’ prenatal psychiatric status and postnatal caregiving on infant biobehavioral regulation: can prenatal programming be modified?. Early Hum Dev. 2008, 84: 249-256. 10.1016/j.earlhumdev.2007.06.004.PubMed Kaplan LA, Evans L, Monk C: Effects of mothers’ prenatal psychiatric status and postnatal caregiving on infant biobehavioral regulation: can prenatal programming be modified?. Early Hum Dev. 2008, 84: 249-256. 10.1016/j.earlhumdev.2007.06.004.PubMed
65.
go back to reference O'Connor TG, Heron J, Golding J, Beveridge M, Glover V: Maternal antenatal anxiety and children's behavioural/emotional problems at 4 years: report from the Avon Longitudinal Study of Parents and Children. Br J Psychiatry. 2002, 180: 502-508. 10.1192/bjp.180.6.502.PubMed O'Connor TG, Heron J, Golding J, Beveridge M, Glover V: Maternal antenatal anxiety and children's behavioural/emotional problems at 4 years: report from the Avon Longitudinal Study of Parents and Children. Br J Psychiatry. 2002, 180: 502-508. 10.1192/bjp.180.6.502.PubMed
66.
go back to reference Van den Bergh BRH, van Calster B, Smits T, van Huffel S, Lagae L: Antenatal maternal anxiety is related to HPA-axis dysregulation and self-reported depressive symptoms in adolescence: a prospective study on the fetal origins of depressed mood. Neuropsychopharmacology. 2008, 33: 536-545. 10.1038/sj.npp.1301450.PubMed Van den Bergh BRH, van Calster B, Smits T, van Huffel S, Lagae L: Antenatal maternal anxiety is related to HPA-axis dysregulation and self-reported depressive symptoms in adolescence: a prospective study on the fetal origins of depressed mood. Neuropsychopharmacology. 2008, 33: 536-545. 10.1038/sj.npp.1301450.PubMed
67.
go back to reference Glover V: Annual research review: prenatal stress and the origins of psychopathology: an evolutionary perspective. J Child Psychol Psychiatry. 2011, 52: 356-367. 10.1111/j.1469-7610.2011.02371.x.PubMed Glover V: Annual research review: prenatal stress and the origins of psychopathology: an evolutionary perspective. J Child Psychol Psychiatry. 2011, 52: 356-367. 10.1111/j.1469-7610.2011.02371.x.PubMed
68.
go back to reference Van den Bergh BR, Mulder EJ, Mennes M, Glover V: Antenatal maternal anxiety and stress and the neurobehavioural development of the fetus and child: links and possible mechanisms. A review. Neurosci Biobehav Rev. 2005, 29: 237-258. 10.1016/j.neubiorev.2004.10.007.PubMed Van den Bergh BR, Mulder EJ, Mennes M, Glover V: Antenatal maternal anxiety and stress and the neurobehavioural development of the fetus and child: links and possible mechanisms. A review. Neurosci Biobehav Rev. 2005, 29: 237-258. 10.1016/j.neubiorev.2004.10.007.PubMed
69.
go back to reference Räikkönen K, Seckl J, Pesonen A-K, Simons A, Van den Bergh B: Stress, glucocorticoids and liquorice in human pregnancy: programmers of the offspring brain. Stress. 2011, 14: 590-603.PubMed Räikkönen K, Seckl J, Pesonen A-K, Simons A, Van den Bergh B: Stress, glucocorticoids and liquorice in human pregnancy: programmers of the offspring brain. Stress. 2011, 14: 590-603.PubMed
70.
go back to reference Khashan AS, Abel KM, McNamee R, Pedersen MG, Webb RT, Baker PN, Kenny LC, Mortensen PB: Higher risk of offspring schizophrenia following antenatal maternal exposure to severe adverse life events. Arch Gen Psychiatry. 2008, 65: 146-152. 10.1001/archgenpsychiatry.2007.20.PubMed Khashan AS, Abel KM, McNamee R, Pedersen MG, Webb RT, Baker PN, Kenny LC, Mortensen PB: Higher risk of offspring schizophrenia following antenatal maternal exposure to severe adverse life events. Arch Gen Psychiatry. 2008, 65: 146-152. 10.1001/archgenpsychiatry.2007.20.PubMed
71.
go back to reference Spauwen J, Krabbendam L, Lieb R, Wittchen HU, van Os J: Early maternal stress and health behaviours and offspring expression of psychosis in adolescence. Acta Psychiatr Scand. 2004, 110: 356-364. 10.1111/j.1600-0447.2004.00429.x.PubMed Spauwen J, Krabbendam L, Lieb R, Wittchen HU, van Os J: Early maternal stress and health behaviours and offspring expression of psychosis in adolescence. Acta Psychiatr Scand. 2004, 110: 356-364. 10.1111/j.1600-0447.2004.00429.x.PubMed
72.
go back to reference Kinney DK, Miller AM, Crowley DJ, Huang E, Gerber E: Autism prevalence following prenatal exposure to hurricanes and tropical storms in Louisiana. J Autism Dev Disord. 2008, 38: 481-488. 10.1007/s10803-007-0414-0.PubMed Kinney DK, Miller AM, Crowley DJ, Huang E, Gerber E: Autism prevalence following prenatal exposure to hurricanes and tropical storms in Louisiana. J Autism Dev Disord. 2008, 38: 481-488. 10.1007/s10803-007-0414-0.PubMed
73.
go back to reference Watson JB, Mednick SA, Huttunen M, Wang X: Prenatal teratogens and the development of adult mental illness. Dev Psychopathol. 1999, 11: 457-466. 10.1017/S0954579499002151.PubMed Watson JB, Mednick SA, Huttunen M, Wang X: Prenatal teratogens and the development of adult mental illness. Dev Psychopathol. 1999, 11: 457-466. 10.1017/S0954579499002151.PubMed
74.
go back to reference Loomans EM, van der Stelt O, van Eijsden M, Gemke RJBJ, Vrijkotte T, van den Bergh BR: Antenatal maternal anxiety is associated with problem behaviour at age five. Early Hum Dev. 2011, 87: 565-570. 10.1016/j.earlhumdev.2011.04.014.PubMed Loomans EM, van der Stelt O, van Eijsden M, Gemke RJBJ, Vrijkotte T, van den Bergh BR: Antenatal maternal anxiety is associated with problem behaviour at age five. Early Hum Dev. 2011, 87: 565-570. 10.1016/j.earlhumdev.2011.04.014.PubMed
75.
go back to reference O'Connor TG, Heron J, Golding J, Glover V, the ALSPAC Study Team: Maternal antenatal anxiety and behavioural/ emotional problems in children: a test of a programming hypothesis. J Child Psychol Psychiatry. 2003, 44: 1025-1036. 10.1111/1469-7610.00187.PubMed O'Connor TG, Heron J, Golding J, Glover V, the ALSPAC Study Team: Maternal antenatal anxiety and behavioural/ emotional problems in children: a test of a programming hypothesis. J Child Psychol Psychiatry. 2003, 44: 1025-1036. 10.1111/1469-7610.00187.PubMed
76.
go back to reference Clavarino AM, Mamun AA, O'Callaghan M, Aird R, Bor W, O'Callaghan F, Williams GM, Marrington S, Najman JM, Alati R: Maternal anxiety and attention problems in children at 5 and 14 years. J Atten Disord. 2010, 13: 658-667. 10.1177/1087054709347203.PubMed Clavarino AM, Mamun AA, O'Callaghan M, Aird R, Bor W, O'Callaghan F, Williams GM, Marrington S, Najman JM, Alati R: Maternal anxiety and attention problems in children at 5 and 14 years. J Atten Disord. 2010, 13: 658-667. 10.1177/1087054709347203.PubMed
77.
go back to reference Robinson M, Oddy WH, Li J, Kendall GE, de Klerk NH, Silburn SR, Zubrick SR, Newnham JP, Stanley FJ, Mattes E: Pre- and postnatal influences on preschool mental health: a large-scale cohort study. J Child Psychol Psychiatry. 2008, 49: 1118-1128. 10.1111/j.1469-7610.2008.01955.x.PubMed Robinson M, Oddy WH, Li J, Kendall GE, de Klerk NH, Silburn SR, Zubrick SR, Newnham JP, Stanley FJ, Mattes E: Pre- and postnatal influences on preschool mental health: a large-scale cohort study. J Child Psychol Psychiatry. 2008, 49: 1118-1128. 10.1111/j.1469-7610.2008.01955.x.PubMed
78.
go back to reference Mayes LC, Ward A: Principles of neurobehavioral teratology. Neurodevelopmental Mech Psychopathol. 2003, 3-33. Mayes LC, Ward A: Principles of neurobehavioral teratology. Neurodevelopmental Mech Psychopathol. 2003, 3-33.
79.
go back to reference Obican S, Scialli AR: Teratogenic exposures. Am J Med Genet C Semin Med Genet. 2011, 157C: 150-169.PubMed Obican S, Scialli AR: Teratogenic exposures. Am J Med Genet C Semin Med Genet. 2011, 157C: 150-169.PubMed
80.
go back to reference Vandenberg LN, Colborn T, Hayes TB, Heindel JJ, Jacobs DR, Lee D-H, Shioda T, Soto AM, vom Saal FS, Welshons WV: Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endocr Rev. 2012, 33: 378-455. 10.1210/er.2011-1050.PubMedPubMedCentral Vandenberg LN, Colborn T, Hayes TB, Heindel JJ, Jacobs DR, Lee D-H, Shioda T, Soto AM, vom Saal FS, Welshons WV: Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endocr Rev. 2012, 33: 378-455. 10.1210/er.2011-1050.PubMedPubMedCentral
81.
go back to reference Lewis MW, Misra S, Johnson HL, Rosen TS: Neurological and developmental outcomes of prenatally cocaine-exposed offspring from 12 to 36 months. Am J Drug Alcohol Abuse. 2004, 30: 299-320. 10.1081/ADA-120037380.PubMed Lewis MW, Misra S, Johnson HL, Rosen TS: Neurological and developmental outcomes of prenatally cocaine-exposed offspring from 12 to 36 months. Am J Drug Alcohol Abuse. 2004, 30: 299-320. 10.1081/ADA-120037380.PubMed
82.
go back to reference McDonald SD, Walker M, Perkins SL, Beyene J, Murphy K, Gibb W, Ohlsson A: The effect of tobacco exposure on the fetal hypothalamic-pituitary-adrenal axis. Bjog. 2006, 113: 1289-1295. 10.1111/j.1471-0528.2006.01089.x.PubMed McDonald SD, Walker M, Perkins SL, Beyene J, Murphy K, Gibb W, Ohlsson A: The effect of tobacco exposure on the fetal hypothalamic-pituitary-adrenal axis. Bjog. 2006, 113: 1289-1295. 10.1111/j.1471-0528.2006.01089.x.PubMed
83.
go back to reference Stene-Larsen K, Borge AIH, Vollrath ME: Maternal smoking in pregnancy and externalizing behavior in 18-month-old children: results from a population-based prospective study. J Am Acad Child Adolesc Psychiatr. 2009, 48: 283-289. 10.1097/CHI.0b013e318195bcfb. Stene-Larsen K, Borge AIH, Vollrath ME: Maternal smoking in pregnancy and externalizing behavior in 18-month-old children: results from a population-based prospective study. J Am Acad Child Adolesc Psychiatr. 2009, 48: 283-289. 10.1097/CHI.0b013e318195bcfb.
84.
go back to reference Lester BM, Bagner DM, Liu J, LaGasse LL, Seifer R, Bauer CR, Shankaran S, Bada H, Higgins RD, Das A: Infant neurobehavioral dysregulation: behavior problems in children with prenatal substance exposure. Pediatrics. 2009, 124: 1355-1362. 10.1542/peds.2008-2898.PubMedPubMedCentral Lester BM, Bagner DM, Liu J, LaGasse LL, Seifer R, Bauer CR, Shankaran S, Bada H, Higgins RD, Das A: Infant neurobehavioral dysregulation: behavior problems in children with prenatal substance exposure. Pediatrics. 2009, 124: 1355-1362. 10.1542/peds.2008-2898.PubMedPubMedCentral
85.
go back to reference Ebrahim SH, Floyd RL, Merritt RK, Decoufle P, Holtzman D: Trends in pregnancy-related smoking rates in the United States, 1987–1996. JAMA. 2000, 283: 361-366. 10.1001/jama.283.3.361.PubMed Ebrahim SH, Floyd RL, Merritt RK, Decoufle P, Holtzman D: Trends in pregnancy-related smoking rates in the United States, 1987–1996. JAMA. 2000, 283: 361-366. 10.1001/jama.283.3.361.PubMed
86.
go back to reference Ethen MK, Ramadhani TA, Scheuerle AE, Canfield MA, Wyszynski DF, Druschel CM, Romitti PA: Alcohol consumption by women before and during pregnancy. Matern Child Health J. 2009, 13: 274-285. 10.1007/s10995-008-0328-2.PubMed Ethen MK, Ramadhani TA, Scheuerle AE, Canfield MA, Wyszynski DF, Druschel CM, Romitti PA: Alcohol consumption by women before and during pregnancy. Matern Child Health J. 2009, 13: 274-285. 10.1007/s10995-008-0328-2.PubMed
87.
go back to reference Cooper WO, Willy ME, Pont SJ, Ray WA: Increasing use of antidepressants in pregnancy. Am J Obstet Gynecol. 2007, 196: 544.PubMed Cooper WO, Willy ME, Pont SJ, Ray WA: Increasing use of antidepressants in pregnancy. Am J Obstet Gynecol. 2007, 196: 544.PubMed
88.
go back to reference Pirkle JL, Brody DJ, Gunter EW, Kramer RA, Paschal DC, Flegal KM, Matte TD: The decline in blood lead levels in the United States. JAMA. 1994, 272: 284-291. 10.1001/jama.1994.03520040046039.PubMed Pirkle JL, Brody DJ, Gunter EW, Kramer RA, Paschal DC, Flegal KM, Matte TD: The decline in blood lead levels in the United States. JAMA. 1994, 272: 284-291. 10.1001/jama.1994.03520040046039.PubMed
89.
go back to reference Linnet KM, Dalsgaard S, Obel C, Wisborg K, Henriksen TB, Rodriguez A, Kotimaa A, Moilanen I, Thomsen PH, Olsen J, Jarvelin MR: Maternal lifestyle factors in pregnancy risk of ADHD. Am J Psychiatr. 2003, 160: 1028-1040. 10.1176/appi.ajp.160.6.1028.PubMed Linnet KM, Dalsgaard S, Obel C, Wisborg K, Henriksen TB, Rodriguez A, Kotimaa A, Moilanen I, Thomsen PH, Olsen J, Jarvelin MR: Maternal lifestyle factors in pregnancy risk of ADHD. Am J Psychiatr. 2003, 160: 1028-1040. 10.1176/appi.ajp.160.6.1028.PubMed
90.
go back to reference Rodriguez A, Bohlin G: Are maternal smoking and stress during pregnancy related to ADHD symptoms in children?. J Child Psychol Psychiatry. 2005, 46: 246-254. 10.1111/j.1469-7610.2004.00359.x.PubMed Rodriguez A, Bohlin G: Are maternal smoking and stress during pregnancy related to ADHD symptoms in children?. J Child Psychol Psychiatry. 2005, 46: 246-254. 10.1111/j.1469-7610.2004.00359.x.PubMed
91.
go back to reference Tiesler CM, Chen CM, Sausenthaler S, Herbarth O, Lehmann I, Schaaf B, Kramer U, von Berg A, von Kries R, Wichmann HE, Heinrich J: Passive smoking and behavioural problems in children: results from the LISAplus prospective birth cohort study. Environ Res. 2011, 111: 1173-1179. 10.1016/j.envres.2011.06.011.PubMed Tiesler CM, Chen CM, Sausenthaler S, Herbarth O, Lehmann I, Schaaf B, Kramer U, von Berg A, von Kries R, Wichmann HE, Heinrich J: Passive smoking and behavioural problems in children: results from the LISAplus prospective birth cohort study. Environ Res. 2011, 111: 1173-1179. 10.1016/j.envres.2011.06.011.PubMed
92.
go back to reference Braun JM, Kahn RS, Froehlich T, Auinger P, Lanphear BP: Exposures to environmental toxicants and attention deficit hyperactivity disorder in U.S. children. Environ Health Perspect. 2006, 114: 1904-1909.PubMedPubMedCentral Braun JM, Kahn RS, Froehlich T, Auinger P, Lanphear BP: Exposures to environmental toxicants and attention deficit hyperactivity disorder in U.S. children. Environ Health Perspect. 2006, 114: 1904-1909.PubMedPubMedCentral
93.
go back to reference Brion MJ, Victora C, Matijasevich A, Horta B, Anselmi L, Steer C, Menezes AM, Lawlor DA, Davey Smith G: Maternal smoking and child psychological problems: disentangling causal and noncausal effects. Pediatrics. 2010, 126: e57-e65. 10.1542/peds.2009-2754.PubMedPubMedCentral Brion MJ, Victora C, Matijasevich A, Horta B, Anselmi L, Steer C, Menezes AM, Lawlor DA, Davey Smith G: Maternal smoking and child psychological problems: disentangling causal and noncausal effects. Pediatrics. 2010, 126: e57-e65. 10.1542/peds.2009-2754.PubMedPubMedCentral
94.
go back to reference Hsieh CJ, Jeng SF, Su YN, Liao HF, Hsieh WS, Wu KY, Chen PC: CYP1A1 modifies the effect of maternal exposure to environmental tobacco smoke on child behavior. Nicotine Tob Res. 2010, 12: 1108-1117. 10.1093/ntr/ntq157.PubMed Hsieh CJ, Jeng SF, Su YN, Liao HF, Hsieh WS, Wu KY, Chen PC: CYP1A1 modifies the effect of maternal exposure to environmental tobacco smoke on child behavior. Nicotine Tob Res. 2010, 12: 1108-1117. 10.1093/ntr/ntq157.PubMed
95.
go back to reference Liu J, Leung PW, McCauley L, Ai Y, Pinto-Martin J: Mother's environmental tobacco smoke exposure during pregnancy and externalizing behavior problems in children. Neurotoxicology. 2013, 34: 167-174.PubMed Liu J, Leung PW, McCauley L, Ai Y, Pinto-Martin J: Mother's environmental tobacco smoke exposure during pregnancy and externalizing behavior problems in children. Neurotoxicology. 2013, 34: 167-174.PubMed
96.
go back to reference Twardella D, Bolte G, Fromme H, Wildner M, von Kries R: Exposure to secondhand tobacco smoke and child behaviour - results from a cross-sectional study among preschool children in Bavaria. Acta Paediatr. 2010, 99: 106-111.PubMed Twardella D, Bolte G, Fromme H, Wildner M, von Kries R: Exposure to secondhand tobacco smoke and child behaviour - results from a cross-sectional study among preschool children in Bavaria. Acta Paediatr. 2010, 99: 106-111.PubMed
97.
go back to reference Ruckinger S, Rzehak P, Chen CM, Sausenthaler S, Koletzko S, Bauer CP, Hoffmann U, Kramer U, Berdel D, von Berg A, et al: Prenatal and postnatal tobacco exposure and behavioral problems in 10-year-old children: results from the GINI-plus prospective birth cohort study. Environ Health Perspect. 2010, 118: 150-154.PubMed Ruckinger S, Rzehak P, Chen CM, Sausenthaler S, Koletzko S, Bauer CP, Hoffmann U, Kramer U, Berdel D, von Berg A, et al: Prenatal and postnatal tobacco exposure and behavioral problems in 10-year-old children: results from the GINI-plus prospective birth cohort study. Environ Health Perspect. 2010, 118: 150-154.PubMed
98.
go back to reference Langley K, Heron J, Smith GD, Thapar A: Maternal and paternal smoking during pregnancy and risk of ADHD symptoms in offspring: testing for intrauterine effects. Am J Epidemiol. 2012, 176: 261-268. 10.1093/aje/kwr510.PubMedPubMedCentral Langley K, Heron J, Smith GD, Thapar A: Maternal and paternal smoking during pregnancy and risk of ADHD symptoms in offspring: testing for intrauterine effects. Am J Epidemiol. 2012, 176: 261-268. 10.1093/aje/kwr510.PubMedPubMedCentral
99.
go back to reference Thapar A, Rice F, Hay D, Boivin J, Langley K, van den Bree M, Rutter M, Harold G: Prenatal smoking might not cause attention-deficit/hyperactivity disorder: evidence from a novel design. Biol Psychiatry. 2009, 66: 722-727. 10.1016/j.biopsych.2009.05.032.PubMedPubMedCentral Thapar A, Rice F, Hay D, Boivin J, Langley K, van den Bree M, Rutter M, Harold G: Prenatal smoking might not cause attention-deficit/hyperactivity disorder: evidence from a novel design. Biol Psychiatry. 2009, 66: 722-727. 10.1016/j.biopsych.2009.05.032.PubMedPubMedCentral
100.
go back to reference Buschgens CJ, Swinkels SH, van Aken MA, Ormel J, Verhulst FC, Buitelaar JK: Externalizing behaviors in preadolescents: familial risk to externalizing behaviors, prenatal and perinatal risks, and their interactions. Eur Child Adolesc Psychiatry. 2009, 18: 65-74. 10.1007/s00787-008-0704-x.PubMed Buschgens CJ, Swinkels SH, van Aken MA, Ormel J, Verhulst FC, Buitelaar JK: Externalizing behaviors in preadolescents: familial risk to externalizing behaviors, prenatal and perinatal risks, and their interactions. Eur Child Adolesc Psychiatry. 2009, 18: 65-74. 10.1007/s00787-008-0704-x.PubMed
101.
go back to reference Streissguth AP, Barr HM, Sampson PD: Moderate prenatal alcohol exposure: effects on child IQ and learning problems at age 7 1/2 years. Alcohol Clin Exp Res. 1990, 14: 662-669. 10.1111/j.1530-0277.1990.tb01224.x.PubMed Streissguth AP, Barr HM, Sampson PD: Moderate prenatal alcohol exposure: effects on child IQ and learning problems at age 7 1/2 years. Alcohol Clin Exp Res. 1990, 14: 662-669. 10.1111/j.1530-0277.1990.tb01224.x.PubMed
102.
go back to reference Sood B, Delaney-Black V, Covington C, Nordstrom-Klee B, Ager J, Templin T, Janisse J, Martier S, Sokol RJ: Prenatal alcohol exposure and childhood behavior at age 6 to 7 years: I. dose–response effect. Pediatrics. 2001, 108: e34-e34. 10.1542/peds.108.2.e34.PubMed Sood B, Delaney-Black V, Covington C, Nordstrom-Klee B, Ager J, Templin T, Janisse J, Martier S, Sokol RJ: Prenatal alcohol exposure and childhood behavior at age 6 to 7 years: I. dose–response effect. Pediatrics. 2001, 108: e34-e34. 10.1542/peds.108.2.e34.PubMed
103.
go back to reference Bada HS, Das A, Bauer CR, Shankaran S, Lester B, LaGasse L, Hammond J, Wright LL, Higgins R: Impact of prenatal cocaine exposure on child behavior problems through school age. Pediatrics. 2007, 119: e348-e359. 10.1542/peds.2006-1404.PubMed Bada HS, Das A, Bauer CR, Shankaran S, Lester B, LaGasse L, Hammond J, Wright LL, Higgins R: Impact of prenatal cocaine exposure on child behavior problems through school age. Pediatrics. 2007, 119: e348-e359. 10.1542/peds.2006-1404.PubMed
104.
go back to reference Savage J, Brodsky NL, Malmud E, Giannetta JM, Hurt H: Attentional functioning and impulse control in cocaine-exposed and control children at age ten years. J Dev Behav Pediatr. 2005, 26: 42-47.PubMed Savage J, Brodsky NL, Malmud E, Giannetta JM, Hurt H: Attentional functioning and impulse control in cocaine-exposed and control children at age ten years. J Dev Behav Pediatr. 2005, 26: 42-47.PubMed
105.
go back to reference LaGasse LL, Derauf C, Smith LM, Newman E, Shah R, Neal C, Arria A, Huestis MA, DellaGrotta S, Lin H, Danereau L, Lester BM: Prenatal methamphetamine exposure and childhood behavior problems at 3 and 5 years of age. Pediatrics. 2012, 129: 681-688. 10.1542/peds.2011-2209.PubMedPubMedCentral LaGasse LL, Derauf C, Smith LM, Newman E, Shah R, Neal C, Arria A, Huestis MA, DellaGrotta S, Lin H, Danereau L, Lester BM: Prenatal methamphetamine exposure and childhood behavior problems at 3 and 5 years of age. Pediatrics. 2012, 129: 681-688. 10.1542/peds.2011-2209.PubMedPubMedCentral
106.
go back to reference Goldschmidt L, Day NL, Richardson GA: Effects of prenatal marijuana exposure on child behavior problems at age 10. Neurotoxicol Teratol. 2000, 22: 325-336. 10.1016/S0892-0362(00)00066-0.PubMed Goldschmidt L, Day NL, Richardson GA: Effects of prenatal marijuana exposure on child behavior problems at age 10. Neurotoxicol Teratol. 2000, 22: 325-336. 10.1016/S0892-0362(00)00066-0.PubMed
107.
go back to reference Day NL, Leech SL, Goldschmidt L: The effects of prenatal marijuana exposure on delinquent behaviors are mediated by measures of neurocognitive functioning. Neurotoxicol Teratol. 2011, 33: 129-136. 10.1016/j.ntt.2010.07.006.PubMedPubMedCentral Day NL, Leech SL, Goldschmidt L: The effects of prenatal marijuana exposure on delinquent behaviors are mediated by measures of neurocognitive functioning. Neurotoxicol Teratol. 2011, 33: 129-136. 10.1016/j.ntt.2010.07.006.PubMedPubMedCentral
108.
go back to reference Andrade SE, Raebel MA, Brown J, Lane K, Livingston J, Boudreau D, Rolnick SJ, Roblin D, Smith DH, Willy ME, Staffa JA, Platt R: Use of antidepressant medications during pregnancy: a multisite study. Am J Obstet Gynecol. 2008, 198: 194-e191-195PubMed Andrade SE, Raebel MA, Brown J, Lane K, Livingston J, Boudreau D, Rolnick SJ, Roblin D, Smith DH, Willy ME, Staffa JA, Platt R: Use of antidepressant medications during pregnancy: a multisite study. Am J Obstet Gynecol. 2008, 198: 194-e191-195PubMed
109.
go back to reference Oberlander TF, Warburton W, Misri S, Aghajanian J, Hertzman C: Neonatal outcomes after prenatal exposure to selective serotonin reuptake inhibitor antidepressants and maternal depression using population-based linked health data. Arch Gen Psychiatry. 2006, 63: 898-906. 10.1001/archpsyc.63.8.898.PubMed Oberlander TF, Warburton W, Misri S, Aghajanian J, Hertzman C: Neonatal outcomes after prenatal exposure to selective serotonin reuptake inhibitor antidepressants and maternal depression using population-based linked health data. Arch Gen Psychiatry. 2006, 63: 898-906. 10.1001/archpsyc.63.8.898.PubMed
110.
go back to reference Lewis AJ, Bailey C, Galbally M: Anti-depressant use during pregnancy in Australia: findings from the Longitudinal Study of Australian Children. Aust N Z J Public Health. 2012, 36: 487-488. 10.1111/j.1753-6405.2012.00917.x.PubMed Lewis AJ, Bailey C, Galbally M: Anti-depressant use during pregnancy in Australia: findings from the Longitudinal Study of Australian Children. Aust N Z J Public Health. 2012, 36: 487-488. 10.1111/j.1753-6405.2012.00917.x.PubMed
111.
go back to reference Malm H, Artama M, Gissler M, Ritvanen A: Selective serotonin reuptake inhibitors and risk for major congenital anomalies. Obstet Gynecol. 2011, 118: 111-10.1097/AOG.0b013e318220edcc.PubMed Malm H, Artama M, Gissler M, Ritvanen A: Selective serotonin reuptake inhibitors and risk for major congenital anomalies. Obstet Gynecol. 2011, 118: 111-10.1097/AOG.0b013e318220edcc.PubMed
112.
go back to reference Galbally M, Roberts M, Buist A: Mood stabilizers in pregnancy: a systematic review. Aust N Z J Psychiatry. 2010, 44: 967-977.PubMed Galbally M, Roberts M, Buist A: Mood stabilizers in pregnancy: a systematic review. Aust N Z J Psychiatry. 2010, 44: 967-977.PubMed
113.
go back to reference Einarson A, Boskovic R: Use and safety of antipsychotic drugs during pregnancy. J Psychiatr Pract. 2009, 15: 183-192. 10.1097/01.pra.0000351878.45260.94.PubMed Einarson A, Boskovic R: Use and safety of antipsychotic drugs during pregnancy. J Psychiatr Pract. 2009, 15: 183-192. 10.1097/01.pra.0000351878.45260.94.PubMed
114.
go back to reference Einarson A, Einarson TR: Maternal use of antipsychotics in early pregnancy: little evidence of increased risk of congenital malformations. Evid Based Ment Health. 2009, 12: 29-10.1136/ebmh.12.1.29.PubMed Einarson A, Einarson TR: Maternal use of antipsychotics in early pregnancy: little evidence of increased risk of congenital malformations. Evid Based Ment Health. 2009, 12: 29-10.1136/ebmh.12.1.29.PubMed
115.
go back to reference Gentile S: Selective serotonin reuptake inhibitor exposure during early pregnancy and the risk of birth defects. Acta Psychiatr Scand. 2011, 123: 266-275. 10.1111/j.1600-0447.2011.01673.x.PubMed Gentile S: Selective serotonin reuptake inhibitor exposure during early pregnancy and the risk of birth defects. Acta Psychiatr Scand. 2011, 123: 266-275. 10.1111/j.1600-0447.2011.01673.x.PubMed
116.
go back to reference Gentile S, Galbally M: Prenatal exposure to antidepressant medications and neurodevelopmental outcomes: a systematic review. J Affect Disord. 2010, 128: 1-9.PubMed Gentile S, Galbally M: Prenatal exposure to antidepressant medications and neurodevelopmental outcomes: a systematic review. J Affect Disord. 2010, 128: 1-9.PubMed
117.
go back to reference Casper RC, Fleisher BE, Lee-Ancajas JC, Gilles A, Gaylor E, DeBattista A, Hoyme HE: Follow-up of children of depressed mothers exposed or not exposed to antidepressant drugs during pregnancy. J Pediatr. 2003, 142: 402-408. 10.1067/mpd.2003.139.PubMed Casper RC, Fleisher BE, Lee-Ancajas JC, Gilles A, Gaylor E, DeBattista A, Hoyme HE: Follow-up of children of depressed mothers exposed or not exposed to antidepressant drugs during pregnancy. J Pediatr. 2003, 142: 402-408. 10.1067/mpd.2003.139.PubMed
118.
go back to reference Casper RC, Gilles AA, Fleisher BE, Baran J, Enns G, Lazzeroni LC: Length of prenatal exposure to selective serotonin reuptake inhibitor (SSRI) antidepressants: effects on neonatal adaptation and psychomotor development. Psychopharmacology (Berl). 2011, 217: 211-219. 10.1007/s00213-011-2270-z. Casper RC, Gilles AA, Fleisher BE, Baran J, Enns G, Lazzeroni LC: Length of prenatal exposure to selective serotonin reuptake inhibitor (SSRI) antidepressants: effects on neonatal adaptation and psychomotor development. Psychopharmacology (Berl). 2011, 217: 211-219. 10.1007/s00213-011-2270-z.
119.
go back to reference Galbally M, Lewis AJ, Buist A: Developmental outcomes of children exposed to antidepressants in pregnancy. Aust N Z J Psychiatry. 2011, 45: 393-399. 10.3109/00048674.2010.549995.PubMed Galbally M, Lewis AJ, Buist A: Developmental outcomes of children exposed to antidepressants in pregnancy. Aust N Z J Psychiatry. 2011, 45: 393-399. 10.3109/00048674.2010.549995.PubMed
120.
go back to reference Mortensen J, Olsen J, Larsen H, Bendsen J, Obel C, Sørensen H: Psychomotor development in children exposed in utero to benzodiazepines, antidepressants, neuroleptics, and anti-epileptics. Eur J Epidemiol. 2003, 18: 769-771.PubMed Mortensen J, Olsen J, Larsen H, Bendsen J, Obel C, Sørensen H: Psychomotor development in children exposed in utero to benzodiazepines, antidepressants, neuroleptics, and anti-epileptics. Eur J Epidemiol. 2003, 18: 769-771.PubMed
121.
go back to reference Weikum WM, Oberlander TF, Hensch TK, Werker JF: Prenatal exposure to antidepressants and depressed maternal mood alter trajectory of infant speech perception. Proc Natl Acad Sci. 2012, 109: 17221-17227. 10.1073/pnas.1121263109.PubMedPubMedCentral Weikum WM, Oberlander TF, Hensch TK, Werker JF: Prenatal exposure to antidepressants and depressed maternal mood alter trajectory of infant speech perception. Proc Natl Acad Sci. 2012, 109: 17221-17227. 10.1073/pnas.1121263109.PubMedPubMedCentral
122.
go back to reference Lewis A, Galbally M, Bailey C: Perinatal mental health, antidepressants and neonatal outcomes: findings from the Longitudinal Study of Australian Children. Neonatal Paediatr Child Health Nurs. 2012, 15: 22-28. Lewis A, Galbally M, Bailey C: Perinatal mental health, antidepressants and neonatal outcomes: findings from the Longitudinal Study of Australian Children. Neonatal Paediatr Child Health Nurs. 2012, 15: 22-28.
123.
go back to reference Galbally M, Snellen M, Lewis AJ: A review of the use of psychotropic medication in pregnancy. Current Opinion in Obstetrics and Gynecology. 2011, 23: 408-414. 10.1097/GCO.0b013e32834b92f3.PubMed Galbally M, Snellen M, Lewis AJ: A review of the use of psychotropic medication in pregnancy. Current Opinion in Obstetrics and Gynecology. 2011, 23: 408-414. 10.1097/GCO.0b013e32834b92f3.PubMed
124.
go back to reference Lewis AJ, Galbally M, Opie G, Buist A: Neonatal growth outcomes at birth and one month postpartum following in utero exposure to antidepressant medication. Aust N Z J Psychiatry. 2010, 44: 482-487. 10.3109/00048670903559593.PubMed Lewis AJ, Galbally M, Opie G, Buist A: Neonatal growth outcomes at birth and one month postpartum following in utero exposure to antidepressant medication. Aust N Z J Psychiatry. 2010, 44: 482-487. 10.3109/00048670903559593.PubMed
125.
go back to reference Galbally M, Lewis AJ, Lum J, Buist A: Serotonin discontinuation syndrome following in utero exposure to antidepressant medication: prospective controlled study. Aust N Z J Psychiatry. 2009, 43: 846-854. 10.1080/00048670903107583.PubMed Galbally M, Lewis AJ, Lum J, Buist A: Serotonin discontinuation syndrome following in utero exposure to antidepressant medication: prospective controlled study. Aust N Z J Psychiatry. 2009, 43: 846-854. 10.1080/00048670903107583.PubMed
126.
go back to reference Galbally M, Snellen M, Lewis AJ: A review of the use of psychotropic medication in pregnancy. Curr Opin Obstet Gynecol. 2011, Publish Ahead of Print:10.1097/GCO.1090b1013e32834b32892f32833 Galbally M, Snellen M, Lewis AJ: A review of the use of psychotropic medication in pregnancy. Curr Opin Obstet Gynecol. 2011, Publish Ahead of Print:10.1097/GCO.1090b1013e32834b32892f32833
127.
go back to reference Austin MP, Kildea S, Sullivan E: Maternal mortality and psychiatric morbidity in the perinatal period: challenges and opportunities for prevention in the Australian setting. Med J Aust. 2007, 186: 364-367.PubMed Austin MP, Kildea S, Sullivan E: Maternal mortality and psychiatric morbidity in the perinatal period: challenges and opportunities for prevention in the Australian setting. Med J Aust. 2007, 186: 364-367.PubMed
128.
go back to reference Schnaas L, Rothenberg SJ, Flores M-F, Martinez S, Hernandez C, Osorio E, Velasco SR, Perroni E: Reduced intellectual development in children with prenatal lead exposure. Environ Health Perspect. 2005, 114: 791-797. 10.1289/ehp.8552.PubMedCentral Schnaas L, Rothenberg SJ, Flores M-F, Martinez S, Hernandez C, Osorio E, Velasco SR, Perroni E: Reduced intellectual development in children with prenatal lead exposure. Environ Health Perspect. 2005, 114: 791-797. 10.1289/ehp.8552.PubMedCentral
129.
go back to reference Wasserman GA, Staghezza-Jaramillo B, Shrout P, Popovac D, Graziano J: The effect of lead exposure on behavior problems in preschool children. Am J Public Health. 1998, 88: 481-486. 10.2105/AJPH.88.3.481.PubMedPubMedCentral Wasserman GA, Staghezza-Jaramillo B, Shrout P, Popovac D, Graziano J: The effect of lead exposure on behavior problems in preschool children. Am J Public Health. 1998, 88: 481-486. 10.2105/AJPH.88.3.481.PubMedPubMedCentral
130.
go back to reference Dietrich KN, Ris MD, Succop PA, Berger OG, Bornschein RL: Early exposure to lead and juvenile delinquency. Neurotoxicol Teratol. 2001, 23: 511-518. 10.1016/S0892-0362(01)00184-2.PubMed Dietrich KN, Ris MD, Succop PA, Berger OG, Bornschein RL: Early exposure to lead and juvenile delinquency. Neurotoxicol Teratol. 2001, 23: 511-518. 10.1016/S0892-0362(01)00184-2.PubMed
131.
go back to reference Tong S, Baghurst PA, Sawyer MG, Burns J, McMichael AJ: Declining blood lead levels and changes in cognitive function during childhood: the Port Pirie Cohort Study. JAMA. 1998, 280: 1915-1919. 10.1001/jama.280.22.1915.PubMed Tong S, Baghurst PA, Sawyer MG, Burns J, McMichael AJ: Declining blood lead levels and changes in cognitive function during childhood: the Port Pirie Cohort Study. JAMA. 1998, 280: 1915-1919. 10.1001/jama.280.22.1915.PubMed
132.
go back to reference Canfield RL, Henderson CR, Cory-Slechta DA, Cox C, Jusko TA, Lanphear BP: Intellectual impairment in children with blood lead concentrations below 10 microg per deciliter. N Engl J Med. 2003, 348: 1517-1526. 10.1056/NEJMoa022848.PubMedPubMedCentral Canfield RL, Henderson CR, Cory-Slechta DA, Cox C, Jusko TA, Lanphear BP: Intellectual impairment in children with blood lead concentrations below 10 microg per deciliter. N Engl J Med. 2003, 348: 1517-1526. 10.1056/NEJMoa022848.PubMedPubMedCentral
133.
go back to reference Huang PC, Su PH, Chen HY, Huang HB, Tsai JL, Huang HI, Wang SL: Childhood blood lead levels and intellectual development after ban of leaded gasoline in Taiwan: a 9-year prospective study. Environ Int. 2012, 40: 88-96.PubMed Huang PC, Su PH, Chen HY, Huang HB, Tsai JL, Huang HI, Wang SL: Childhood blood lead levels and intellectual development after ban of leaded gasoline in Taiwan: a 9-year prospective study. Environ Int. 2012, 40: 88-96.PubMed
134.
go back to reference Chen A, Cai B, Dietrich KN, Radcliffe J, Rogan WJ: Lead exposure, IQ, and behavior in urban 5- to 7-year-olds: does lead affect behavior only by lowering IQ?. Pediatrics. 2007, 119: e650-e658. 10.1542/peds.2006-1973.PubMedPubMedCentral Chen A, Cai B, Dietrich KN, Radcliffe J, Rogan WJ: Lead exposure, IQ, and behavior in urban 5- to 7-year-olds: does lead affect behavior only by lowering IQ?. Pediatrics. 2007, 119: e650-e658. 10.1542/peds.2006-1973.PubMedPubMedCentral
135.
go back to reference Wasserman GA, Liu X, Popovac D, Factor-Litvak P, Kline J, Waternaux C, LoIacono N, Graziano JH: The Yugoslavia Prospective Lead Study: contributions of prenatal and postnatal lead exposure to early intelligence. Neurotoxicol Teratol. 2000, 22: 811-818. 10.1016/S0892-0362(00)00106-9.PubMed Wasserman GA, Liu X, Popovac D, Factor-Litvak P, Kline J, Waternaux C, LoIacono N, Graziano JH: The Yugoslavia Prospective Lead Study: contributions of prenatal and postnatal lead exposure to early intelligence. Neurotoxicol Teratol. 2000, 22: 811-818. 10.1016/S0892-0362(00)00106-9.PubMed
136.
go back to reference Lanphear BP, Hornung R, Khoury J, Yolton K, Baghurst P, Bellinger DC, Canfield RL, Dietrich KN, Bornschein R, Greene T, Rothenberg SJ, Needleman HL, Schnaas L, Wasserman G, Graziano J, Roberts R: Low-level environmental lead exposure and children's intellectual function: an international pooled analysis. Environ Health Perspect. 2005, 113: 894-899. 10.1289/ehp.7688.PubMedPubMedCentral Lanphear BP, Hornung R, Khoury J, Yolton K, Baghurst P, Bellinger DC, Canfield RL, Dietrich KN, Bornschein R, Greene T, Rothenberg SJ, Needleman HL, Schnaas L, Wasserman G, Graziano J, Roberts R: Low-level environmental lead exposure and children's intellectual function: an international pooled analysis. Environ Health Perspect. 2005, 113: 894-899. 10.1289/ehp.7688.PubMedPubMedCentral
137.
go back to reference Baghurst PA, McMichael AJ, Wigg NR, Vimpani GV, Robertson EF, Roberts RJ, Tong SL: Environmental exposure to lead and children's intelligence at the age of seven years. The Port Pirie Cohort Study. N Engl J Med. 1992, 327: 1279-1284. 10.1056/NEJM199210293271805.PubMed Baghurst PA, McMichael AJ, Wigg NR, Vimpani GV, Robertson EF, Roberts RJ, Tong SL: Environmental exposure to lead and children's intelligence at the age of seven years. The Port Pirie Cohort Study. N Engl J Med. 1992, 327: 1279-1284. 10.1056/NEJM199210293271805.PubMed
138.
go back to reference Chiodo LM, Jacobson SW, Jacobson JL: Neurodevelopmental effects of postnatal lead exposure at very low levels. Neurotoxicol Teratol. 2004, 26: 359-371. 10.1016/j.ntt.2004.01.010.PubMed Chiodo LM, Jacobson SW, Jacobson JL: Neurodevelopmental effects of postnatal lead exposure at very low levels. Neurotoxicol Teratol. 2004, 26: 359-371. 10.1016/j.ntt.2004.01.010.PubMed
139.
go back to reference Needleman HL, Riess JA, Tobin MJ, Biesecker GE, Greenhouse JB: Bone lead levels and delinquent behavior. JAMA. 1996, 275: 363-369. 10.1001/jama.1996.03530290033034.PubMed Needleman HL, Riess JA, Tobin MJ, Biesecker GE, Greenhouse JB: Bone lead levels and delinquent behavior. JAMA. 1996, 275: 363-369. 10.1001/jama.1996.03530290033034.PubMed
140.
go back to reference Sciarillo WG, Alexander G, Farrell KP: Lead exposure and child behavior. Am J Public Health. 1992, 82: 1356-1360. 10.2105/AJPH.82.10.1356.PubMedPubMedCentral Sciarillo WG, Alexander G, Farrell KP: Lead exposure and child behavior. Am J Public Health. 1992, 82: 1356-1360. 10.2105/AJPH.82.10.1356.PubMedPubMedCentral
141.
go back to reference Burns JM, Baghurst PA, Sawyer MG, McMichael AJ, Tong SL: Lifetime low-level exposure to environmental lead and children's emotional and behavioral development at ages 11–13 years. The Port Pirie Cohort Study. Am J Public Health. 1999, 149: 740-749. Burns JM, Baghurst PA, Sawyer MG, McMichael AJ, Tong SL: Lifetime low-level exposure to environmental lead and children's emotional and behavioral development at ages 11–13 years. The Port Pirie Cohort Study. Am J Public Health. 1999, 149: 740-749.
142.
go back to reference Froehlich TE, Lanphear BP, Auinger P, Hornung R, Epstein JN, Braun J, Kahn RS: Association of tobacco and lead exposures with attention-deficit/hyperactivity disorder. Pediatrics. 2009, 124: e1054-e1063. 10.1542/peds.2009-0738.PubMedPubMedCentral Froehlich TE, Lanphear BP, Auinger P, Hornung R, Epstein JN, Braun J, Kahn RS: Association of tobacco and lead exposures with attention-deficit/hyperactivity disorder. Pediatrics. 2009, 124: e1054-e1063. 10.1542/peds.2009-0738.PubMedPubMedCentral
143.
go back to reference Symeonides C, Ponsonby A-L, Vuillermin P, Anderson V, Sly P: Environmental chemical contributions to ADHD and the externalising disorders of childhood - a review of epidemiological evidence. J Environ Immunol Toxicol. 2013, 1: 92-104. 10.7178/jeit.21. Symeonides C, Ponsonby A-L, Vuillermin P, Anderson V, Sly P: Environmental chemical contributions to ADHD and the externalising disorders of childhood - a review of epidemiological evidence. J Environ Immunol Toxicol. 2013, 1: 92-104. 10.7178/jeit.21.
144.
go back to reference Sagiv SK, Thurston SW, Bellinger DC, Amarasiriwardena C, Korrick SA: Prenatal exposure to mercury and fish consumption during pregnancy and attention-deficit/hyperactivity disorder-related behavior in children. Arch Pediatr Adolesc Med. 2012, 166: 1123-1131. 10.1001/archpediatrics.2012.1286.PubMedPubMedCentral Sagiv SK, Thurston SW, Bellinger DC, Amarasiriwardena C, Korrick SA: Prenatal exposure to mercury and fish consumption during pregnancy and attention-deficit/hyperactivity disorder-related behavior in children. Arch Pediatr Adolesc Med. 2012, 166: 1123-1131. 10.1001/archpediatrics.2012.1286.PubMedPubMedCentral
145.
go back to reference Sagiv SK, Thurston SW, Bellinger DC, Tolbert PE, Altshul LM, Korrick SA: Prenatal organochlorine exposure and behaviors associated with attention deficit hyperactivity disorder in school-aged children. Am J Epidemiol. 2010, 171: 593-601. 10.1093/aje/kwp427.PubMedPubMedCentral Sagiv SK, Thurston SW, Bellinger DC, Tolbert PE, Altshul LM, Korrick SA: Prenatal organochlorine exposure and behaviors associated with attention deficit hyperactivity disorder in school-aged children. Am J Epidemiol. 2010, 171: 593-601. 10.1093/aje/kwp427.PubMedPubMedCentral
146.
go back to reference Wise A, Parham F, Axelrad DA, Guyton KZ, Portier C, Zeise L, Zoeller RT, Woodruff TJ: Upstream adverse effects in risk assessment: a model of polychlorinated biphenyls, thyroid hormone disruption and neurological outcomes in humans. Environ Res. 2012, 117: 90-99.PubMed Wise A, Parham F, Axelrad DA, Guyton KZ, Portier C, Zeise L, Zoeller RT, Woodruff TJ: Upstream adverse effects in risk assessment: a model of polychlorinated biphenyls, thyroid hormone disruption and neurological outcomes in humans. Environ Res. 2012, 117: 90-99.PubMed
147.
go back to reference Jones RL, Homa DM, Meyer PA, Brody DJ, Caldwell KL, Pirkle JL, Brown MJ: Trends in blood lead levels and blood lead testing among US children aged 1 to 5 years, 1988–2004. Pediatrics. 2009, 123: e376-e385. 10.1542/peds.2007-3608.PubMed Jones RL, Homa DM, Meyer PA, Brody DJ, Caldwell KL, Pirkle JL, Brown MJ: Trends in blood lead levels and blood lead testing among US children aged 1 to 5 years, 1988–2004. Pediatrics. 2009, 123: e376-e385. 10.1542/peds.2007-3608.PubMed
148.
go back to reference Noren K, Meironyte D: Certain organochlorine and organobromine contaminants in Swedish human milk in perspective of past 20–30 years. Chemosphere. 2000, 40: 1111-1123. 10.1016/S0045-6535(99)00360-4.PubMed Noren K, Meironyte D: Certain organochlorine and organobromine contaminants in Swedish human milk in perspective of past 20–30 years. Chemosphere. 2000, 40: 1111-1123. 10.1016/S0045-6535(99)00360-4.PubMed
149.
go back to reference Zietz BP, Hoopmann M, Funcke M, Huppmann R, Suchenwirth R, Gierden E: Long-term biomonitoring of polychlorinated biphenyls and organochlorine pesticides in human milk from mothers living in northern Germany. Int J Hyg Environ Health. 2008, 211: 624-638. 10.1016/j.ijheh.2008.04.001.PubMed Zietz BP, Hoopmann M, Funcke M, Huppmann R, Suchenwirth R, Gierden E: Long-term biomonitoring of polychlorinated biphenyls and organochlorine pesticides in human milk from mothers living in northern Germany. Int J Hyg Environ Health. 2008, 211: 624-638. 10.1016/j.ijheh.2008.04.001.PubMed
151.
go back to reference Grandjean P, Landrigan PJ: Developmental neurotoxicity of industrial chemicals. Lancet. 2006, 368: 2167-2178. 10.1016/S0140-6736(06)69665-7.PubMed Grandjean P, Landrigan PJ: Developmental neurotoxicity of industrial chemicals. Lancet. 2006, 368: 2167-2178. 10.1016/S0140-6736(06)69665-7.PubMed
152.
go back to reference Zhu SH, Valbo A: Depression and smoking during pregnancy. Addict Behav. 2002, 27: 649-658. 10.1016/S0306-4603(01)00199-X.PubMed Zhu SH, Valbo A: Depression and smoking during pregnancy. Addict Behav. 2002, 27: 649-658. 10.1016/S0306-4603(01)00199-X.PubMed
153.
go back to reference DiPietro JA, Novak MF, Costigan KA, Atella LD, Reusing SP: Maternal psychological distress during pregnancy in relation to child development at age two. Child Dev. 2006, 77: 573-587. 10.1111/j.1467-8624.2006.00891.x.PubMed DiPietro JA, Novak MF, Costigan KA, Atella LD, Reusing SP: Maternal psychological distress during pregnancy in relation to child development at age two. Child Dev. 2006, 77: 573-587. 10.1111/j.1467-8624.2006.00891.x.PubMed
154.
go back to reference Way BM, Taylor SE: The serotonin transporter promoter polymorphism is associated with cortisol response to psychosocial stress. Biol Psychiatry. 2010, 67: 487-492. 10.1016/j.biopsych.2009.10.021.PubMed Way BM, Taylor SE: The serotonin transporter promoter polymorphism is associated with cortisol response to psychosocial stress. Biol Psychiatry. 2010, 67: 487-492. 10.1016/j.biopsych.2009.10.021.PubMed
155.
go back to reference Davis EP, Sandman CA: The timing of prenatal exposure to maternal cortisol and psychosocial stress is associated with human infant cognitive development. Child Dev. 2010, 81: 131-148. 10.1111/j.1467-8624.2009.01385.x.PubMedPubMedCentral Davis EP, Sandman CA: The timing of prenatal exposure to maternal cortisol and psychosocial stress is associated with human infant cognitive development. Child Dev. 2010, 81: 131-148. 10.1111/j.1467-8624.2009.01385.x.PubMedPubMedCentral
156.
go back to reference Rayen I, van den Hove DL, Prickaerts J, Steinbusch HW, Pawluski JL: Fluoxetine during development reverses the effects of prenatal stress on depressive-like behavior and hippocampal neurogenesis in adolescence. PLoS One. 2011, 6: e24003-10.1371/journal.pone.0024003.PubMedPubMedCentral Rayen I, van den Hove DL, Prickaerts J, Steinbusch HW, Pawluski JL: Fluoxetine during development reverses the effects of prenatal stress on depressive-like behavior and hippocampal neurogenesis in adolescence. PLoS One. 2011, 6: e24003-10.1371/journal.pone.0024003.PubMedPubMedCentral
157.
go back to reference Lee HJ, Kim JW, Yim SV, Kim MJ, Kim SA, Kim YJ, Kim CJ, Chung JH: Fluoxetine enhances cell proliferation and prevents apoptosis in dentate gyrus of maternally separated rats. Mol Psychiatry. 2001, 6: 610-10.1038/sj.mp.4000954. 725–618PubMed Lee HJ, Kim JW, Yim SV, Kim MJ, Kim SA, Kim YJ, Kim CJ, Chung JH: Fluoxetine enhances cell proliferation and prevents apoptosis in dentate gyrus of maternally separated rats. Mol Psychiatry. 2001, 6: 610-10.1038/sj.mp.4000954. 725–618PubMed
158.
go back to reference Weikum WM, Brain U, Chau CM, Grunau RE, Boyce WT, Diamond A, Oberlander TF: Prenatal serotonin reuptake inhibitor (SRI) antidepressant exposure and serotonin transporter promoter genotype (SLC6A4) influence executive functions at 6 years of age. Front Cell Neurosci. 2013, 7: 180.PubMedPubMedCentral Weikum WM, Brain U, Chau CM, Grunau RE, Boyce WT, Diamond A, Oberlander TF: Prenatal serotonin reuptake inhibitor (SRI) antidepressant exposure and serotonin transporter promoter genotype (SLC6A4) influence executive functions at 6 years of age. Front Cell Neurosci. 2013, 7: 180.PubMedPubMedCentral
159.
go back to reference Nulman I, Koren G, Rovet J, Barrera M, Pulver A, Streiner D, Feldman B: Neurodevelopment of children following prenatal exposure to venlafaxine, selective serotonin reuptake inhibitors, or untreated maternal depression. Am J Psychiatry. 2012, 169: 1165-1174.PubMed Nulman I, Koren G, Rovet J, Barrera M, Pulver A, Streiner D, Feldman B: Neurodevelopment of children following prenatal exposure to venlafaxine, selective serotonin reuptake inhibitors, or untreated maternal depression. Am J Psychiatry. 2012, 169: 1165-1174.PubMed
160.
go back to reference Nulman I, Rovet J, Stewart DE, Wolpin J, Pace-Asciak P, Shuhaiber S, Koren G: Child development following exposure to tricyclic antidepressants or fluoxetine throughout fetal life: a prospective, controlled study. Am J Psychiatry. 2002, 159: 1889-1895. 10.1176/appi.ajp.159.11.1889.PubMed Nulman I, Rovet J, Stewart DE, Wolpin J, Pace-Asciak P, Shuhaiber S, Koren G: Child development following exposure to tricyclic antidepressants or fluoxetine throughout fetal life: a prospective, controlled study. Am J Psychiatry. 2002, 159: 1889-1895. 10.1176/appi.ajp.159.11.1889.PubMed
161.
go back to reference Andrews G, Issakidis C, Sanderson K, Corry J, Lapsley H: Utilising survey data to inform public policy: comparison of the cost-effectiveness of treatment of ten mental disorders. Br J Psychiatry. 2004, 184: 526-533. 10.1192/bjp.184.6.526.PubMed Andrews G, Issakidis C, Sanderson K, Corry J, Lapsley H: Utilising survey data to inform public policy: comparison of the cost-effectiveness of treatment of ten mental disorders. Br J Psychiatry. 2004, 184: 526-533. 10.1192/bjp.184.6.526.PubMed
162.
go back to reference Jacka FN, Reavley NJ, Jorm AF, Toumbourou JW, Lewis AJ, Berk M: Prevention of common mental disorders: What can we learn from those who have gone before and where do we go next?. Aust N Z J Psychiatry. 2013, 47: 920-929. 10.1177/0004867413493523.PubMed Jacka FN, Reavley NJ, Jorm AF, Toumbourou JW, Lewis AJ, Berk M: Prevention of common mental disorders: What can we learn from those who have gone before and where do we go next?. Aust N Z J Psychiatry. 2013, 47: 920-929. 10.1177/0004867413493523.PubMed
163.
go back to reference Prince M, Patel V, Saxena S, Maj M, Maselko J, Phillips MR, Rahman A: No health without mental health. Lancet. 2007, 370: 859-877. 10.1016/S0140-6736(07)61238-0.PubMed Prince M, Patel V, Saxena S, Maj M, Maselko J, Phillips MR, Rahman A: No health without mental health. Lancet. 2007, 370: 859-877. 10.1016/S0140-6736(07)61238-0.PubMed
164.
go back to reference Olds DL, Sadler L, Kitzman H: Programs for parents of infants and toddlers: recent evidence from randomized trials. J Child Psychol Psychiatr. 2007, 48: 355-391. 10.1111/j.1469-7610.2006.01702.x. Olds DL, Sadler L, Kitzman H: Programs for parents of infants and toddlers: recent evidence from randomized trials. J Child Psychol Psychiatr. 2007, 48: 355-391. 10.1111/j.1469-7610.2006.01702.x.
165.
go back to reference Olds DL, Kitzman H, Hanks C, Cole R, Anson E, Sidora-Arcoleo K, Luckey DW, Henderson CR, Holmberg J, Tutt RA: Effects of nurse home visiting on maternal and child functioning: age-9 follow-up of a randomized trial. Pediatrics. 2007, 120: e832-e845. 10.1542/peds.2006-2111.PubMedPubMedCentral Olds DL, Kitzman H, Hanks C, Cole R, Anson E, Sidora-Arcoleo K, Luckey DW, Henderson CR, Holmberg J, Tutt RA: Effects of nurse home visiting on maternal and child functioning: age-9 follow-up of a randomized trial. Pediatrics. 2007, 120: e832-e845. 10.1542/peds.2006-2111.PubMedPubMedCentral
166.
go back to reference Olds DL: The nurse-family partnership: an evidence-based preventive intervention. Infant Ment Health J. 2006, 27: 5-25. 10.1002/imhj.20077. Olds DL: The nurse-family partnership: an evidence-based preventive intervention. Infant Ment Health J. 2006, 27: 5-25. 10.1002/imhj.20077.
167.
go back to reference Dennis CL: Psychosocial and psychological interventions for prevention of postnatal depression: systematic review. BMJ. 2005, 331: 15-10.1136/bmj.331.7507.15.PubMedPubMedCentral Dennis CL: Psychosocial and psychological interventions for prevention of postnatal depression: systematic review. BMJ. 2005, 331: 15-10.1136/bmj.331.7507.15.PubMedPubMedCentral
168.
go back to reference Fisher JR, Wynter KH, Rowe HJ: Innovative psycho-educational program to prevent common postpartum mental disorders in primiparous women: a before and after controlled study. BMC Publ Health. 2010, 10: 432-10.1186/1471-2458-10-432. Fisher JR, Wynter KH, Rowe HJ: Innovative psycho-educational program to prevent common postpartum mental disorders in primiparous women: a before and after controlled study. BMC Publ Health. 2010, 10: 432-10.1186/1471-2458-10-432.
169.
go back to reference Lumley J, Austin MP, Mitchell C: Intervening to reduce depression after birth: a systematic review of the randomized trials. Int J Technol Assess Health Care. 2004, 20: 128-144.PubMed Lumley J, Austin MP, Mitchell C: Intervening to reduce depression after birth: a systematic review of the randomized trials. Int J Technol Assess Health Care. 2004, 20: 128-144.PubMed
Metadata
Title
Early life programming as a target for prevention of child and adolescent mental disorders
Authors
Andrew James Lewis
Megan Galbally
Tara Gannon
Christos Symeonides
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Medicine / Issue 1/2014
Electronic ISSN: 1741-7015
DOI
https://doi.org/10.1186/1741-7015-12-33

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