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Published in: Journal of the International Society of Sports Nutrition 1/2006

Open Access 01-06-2006 | Research article

Thermogenic Effect from Nutritionally Enriched Coffee Consumption

Authors: Jay R Hoffman, Jie Kang, Nicholas A Ratamess, Peter F Jennings, Gerald Mangine, Avery D Faigenbaum

Published in: Journal of the International Society of Sports Nutrition | Issue 1/2006

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Abstract

Background

The purpose of this study was to examine the effect of nutritionally enriched JavaFit™ (JF) coffee (450 mg of caffeine, 1200 mg of garcinia cambogia, 360 mg of citrus aurantium extract, and 225 mcg of chromium polynicotinate) on resting oxygen uptake (VO2), respiratory exchange ratio (RER), heart rate (HR), and blood pressure (BP) in healthy and physically active individuals.

Method

Ten subjects (8 male, 2 female; 20.9 ± 1.7 y; 178.1 ± 10.4 cm; 71.8 ± 12.1 kg) underwent two testing sessions administered in a randomized and double-blind fashion. During each session, subjects reported to the Human Performance Laboratory after at least 3-h post-absorptive state and were provided either 354 ml (1.5 cups) of freshly brewed JF or commercially available caffeinated coffee (P). Subjects then rested in a semi-recumbent position for three hours. VO2 and HR were determined every 5 min during the first 30 min and every 10 min during the next 150 min. BP was determined every 15 min during the first 30 min and every 30 min thereafter. Area under the curve (AUC) analysis was computed for VO2, whereas a session-average was calculated for RER, HR and BP.

Results

Initial analysis revealed no significant differences. However, seven of the ten subjects were considered responders to JF (had a higher AUC for VO2during JF than P). Statistical analysis showed the difference between JF and P (12%) to be significantly different in these responders. In addition, the average systolic BP was higher (p < 0.05) in JF (118 ± 7 mmHg) than P (115 ± 8 mmHg) in both the total sample and the subgroup of responders. No differences in average HR and average diastolic BP were observed between JF and P in both the total sample and the subgroup of responders.

Conclusion

It appears that consuming a nutritionally-enriched coffee beverage may increase resting energy expenditure in individuals that are sensitive to the caffeine and herbal coffee supplement. In addition, this supplement also appears to affect cardiovascular dynamics by augmenting systolic arterial blood pressure.
Literature
1.
go back to reference Acheson KJ, Zahorska-Markiewicz B, Pittet PH, Anantharaman K, Jéquier E: Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal and obese individuals. Am J Clin Nutr. 1980, 33: 989–997.CrossRef Acheson KJ, Zahorska-Markiewicz B, Pittet PH, Anantharaman K, Jéquier E: Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal and obese individuals. Am J Clin Nutr. 1980, 33: 989–997.CrossRef
2.
go back to reference Dulloo AG, Geisler CA, Horton T, Collins A, Miller DS: Normal caffeine consumption: Influence on thermogenesis and daily energy expenditure in lean and postobese human volunteers. Am J Clin Nutr. 1989, 49: 44–50.CrossRef Dulloo AG, Geisler CA, Horton T, Collins A, Miller DS: Normal caffeine consumption: Influence on thermogenesis and daily energy expenditure in lean and postobese human volunteers. Am J Clin Nutr. 1989, 49: 44–50.CrossRef
3.
go back to reference Dulloo AG, Duret C, Rohrer D, Girardier L, Mensi N, Fathi M, Chantre P, Vandermander J: Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am J Clin Nutr. 1999, 70: 1040–1045.CrossRef Dulloo AG, Duret C, Rohrer D, Girardier L, Mensi N, Fathi M, Chantre P, Vandermander J: Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am J Clin Nutr. 1999, 70: 1040–1045.CrossRef
4.
go back to reference Roberts AT, de Jonge-Levitan L, Parker CC, Greenway FL: The effect of an herbal supplement containing black tea and caffeine on metabolic parameters in humans. Alt Med Rev. 2005, 10: 321–325. Roberts AT, de Jonge-Levitan L, Parker CC, Greenway FL: The effect of an herbal supplement containing black tea and caffeine on metabolic parameters in humans. Alt Med Rev. 2005, 10: 321–325.
5.
go back to reference Coffey CS, Steiner D, Baker BA, Allison DB: A randomized double-blind placebo-controlled clinical trial of a containing ephedrine, caffeine, and other ingredients from herbal sources for treatment of overweight and obesity in the absence of lifestyle treatment. Int J Obes. 2004, 28: 1411–1419. 10.1038/sj.ijo.0802784.CrossRef Coffey CS, Steiner D, Baker BA, Allison DB: A randomized double-blind placebo-controlled clinical trial of a containing ephedrine, caffeine, and other ingredients from herbal sources for treatment of overweight and obesity in the absence of lifestyle treatment. Int J Obes. 2004, 28: 1411–1419. 10.1038/sj.ijo.0802784.CrossRef
6.
go back to reference Greenway FL, de Jonge L, Blanchard D, Frisard M, Smith SR: Effect of a dietary herbal supplement containing caffeine and ephedra on weight, metabolic rate, and body composition. Obes Res. 2004, 12: 1152–1157.CrossRef Greenway FL, de Jonge L, Blanchard D, Frisard M, Smith SR: Effect of a dietary herbal supplement containing caffeine and ephedra on weight, metabolic rate, and body composition. Obes Res. 2004, 12: 1152–1157.CrossRef
7.
go back to reference Haller CA, Jacob P, Benowitz NL: Enhanced stimulant and metabolic effects of ephedrine and caffeine. Clin Pharmacol Ther. 2004, 75: 259–273. 10.1016/j.clpt.2003.11.375.CrossRef Haller CA, Jacob P, Benowitz NL: Enhanced stimulant and metabolic effects of ephedrine and caffeine. Clin Pharmacol Ther. 2004, 75: 259–273. 10.1016/j.clpt.2003.11.375.CrossRef
8.
go back to reference Vukovich MD, Schoorman R, Heilman C, Jacob P, Benowitz NL: Caffeine-herbal ephedra combination increases resting energy expenditure, heart rate and blood pressure. Clin Exp Pharmacol Physiol. 2005, 32: 47–53. 10.1111/j.1440-1681.2005.04152.x.CrossRef Vukovich MD, Schoorman R, Heilman C, Jacob P, Benowitz NL: Caffeine-herbal ephedra combination increases resting energy expenditure, heart rate and blood pressure. Clin Exp Pharmacol Physiol. 2005, 32: 47–53. 10.1111/j.1440-1681.2005.04152.x.CrossRef
9.
go back to reference Fugh-Berman A, Myers A: Citrus aurantium, an ingredient of dietary supplements marketed for weight loss: Current status of clinical and basic research. Exp Biol Med. 2004, 229: 698–704.CrossRef Fugh-Berman A, Myers A: Citrus aurantium, an ingredient of dietary supplements marketed for weight loss: Current status of clinical and basic research. Exp Biol Med. 2004, 229: 698–704.CrossRef
10.
go back to reference Carpene C, Galitzky J, Fontana E, Atgie C, Lafontan M, Berlan M: Selective activation of beta3-adrenoreceptors by octopamine: comparative studies in mammalian fat cells. Naunyn Schmiedebergs Arch Pharmacol. 1999, 359: 310–321. 10.1007/PL00005357.CrossRef Carpene C, Galitzky J, Fontana E, Atgie C, Lafontan M, Berlan M: Selective activation of beta3-adrenoreceptors by octopamine: comparative studies in mammalian fat cells. Naunyn Schmiedebergs Arch Pharmacol. 1999, 359: 310–321. 10.1007/PL00005357.CrossRef
11.
go back to reference Haller CA, Benowitz NL, Jacob P: Hemodynamic effects of ephedra-free weight-loss supplements in humans. Am J Med. 2005, 118: 998–1003. 10.1016/j.amjmed.2005.02.034.CrossRef Haller CA, Benowitz NL, Jacob P: Hemodynamic effects of ephedra-free weight-loss supplements in humans. Am J Med. 2005, 118: 998–1003. 10.1016/j.amjmed.2005.02.034.CrossRef
12.
go back to reference Crawford V, Scheckenback R, Preuss HG: Effects of niacin-bound chromium supplementation on body composition in overweight African-American women. Diabetes, Obes Metab. 1999, 1: 331–337. 10.1046/j.1463-1326.1999.00055.x.CrossRef Crawford V, Scheckenback R, Preuss HG: Effects of niacin-bound chromium supplementation on body composition in overweight African-American women. Diabetes, Obes Metab. 1999, 1: 331–337. 10.1046/j.1463-1326.1999.00055.x.CrossRef
13.
go back to reference Volpe SL, Huang HW, Larpadisorn K, Lesser II: Effect of chromium supplementation and exercise on body composition, resting metabolic rate and selected biochemical parameters in moderately obese women following an exercise program. J Amer Coll Nutr. 2001, 20: 293–306.CrossRef Volpe SL, Huang HW, Larpadisorn K, Lesser II: Effect of chromium supplementation and exercise on body composition, resting metabolic rate and selected biochemical parameters in moderately obese women following an exercise program. J Amer Coll Nutr. 2001, 20: 293–306.CrossRef
14.
go back to reference Lowenstein JM: Effect of (-)-hydroxycitrate on fatty acid synthesis by rat liver in vivo. J Biol Chem. 1971, 246: 629–632.PubMed Lowenstein JM: Effect of (-)-hydroxycitrate on fatty acid synthesis by rat liver in vivo. J Biol Chem. 1971, 246: 629–632.PubMed
15.
go back to reference Sullivan AC, Triscari J, Hamilton JG, Miller ON, Wheatley VR: Effect of (-)-hydroxycitrate upon the accumulation of lipid in the rat. I Lipogenesis Lipids. 1974, 9: 121–128. 10.1007/BF02532136.CrossRef Sullivan AC, Triscari J, Hamilton JG, Miller ON, Wheatley VR: Effect of (-)-hydroxycitrate upon the accumulation of lipid in the rat. I Lipogenesis Lipids. 1974, 9: 121–128. 10.1007/BF02532136.CrossRef
16.
go back to reference Ohia SE, Awe O, LeDay AM, Opere CA, Bagchi D: Effect of hydroxycitric acid on serotonin release from isolated rat brain cortex. Res Commun Mol Pathol Pharmacol. 2001, 109: 210–216.PubMed Ohia SE, Awe O, LeDay AM, Opere CA, Bagchi D: Effect of hydroxycitric acid on serotonin release from isolated rat brain cortex. Res Commun Mol Pathol Pharmacol. 2001, 109: 210–216.PubMed
17.
go back to reference Heymsfield SB, Allison DB, Vasselli JR, Pietrobelli A, Greenfield D, Nunez C: Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent. JAMA. 1998, 280: 1596–1600. 10.1001/jama.280.18.1596.CrossRef Heymsfield SB, Allison DB, Vasselli JR, Pietrobelli A, Greenfield D, Nunez C: Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent. JAMA. 1998, 280: 1596–1600. 10.1001/jama.280.18.1596.CrossRef
18.
go back to reference Hayamizu K, Ishii Y, Kaneko I, Shen M, Okuhara Y, Shigematsu N, Tomi H, Furuse M, Yoshino G: Effects of garcinia cambogia (hydroxycitric acid) on visceral fat accumulation: A double-blind, randomized, placebo-controlled trial. Curr Ther Res. 2003, 64: 551–567. 10.1016/j.curtheres.2003.08.006.CrossRef Hayamizu K, Ishii Y, Kaneko I, Shen M, Okuhara Y, Shigematsu N, Tomi H, Furuse M, Yoshino G: Effects of garcinia cambogia (hydroxycitric acid) on visceral fat accumulation: A double-blind, randomized, placebo-controlled trial. Curr Ther Res. 2003, 64: 551–567. 10.1016/j.curtheres.2003.08.006.CrossRef
19.
go back to reference Preuss HG, Bagchi D, Bagchi M, Rao CVS, Dey DK, Satyanarayana S: Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss. Diabetes, Obes Metab. 2004, 6: 171–180. 10.1111/j.1462-8902.2004.00328.x.CrossRef Preuss HG, Bagchi D, Bagchi M, Rao CVS, Dey DK, Satyanarayana S: Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss. Diabetes, Obes Metab. 2004, 6: 171–180. 10.1111/j.1462-8902.2004.00328.x.CrossRef
20.
go back to reference McNair DM, Lorr M, Droppleman LF: Profile of Mood States Manual. 1971, San Diego, CA: Educational and Industrial Testing Service McNair DM, Lorr M, Droppleman LF: Profile of Mood States Manual. 1971, San Diego, CA: Educational and Industrial Testing Service
21.
go back to reference Flint A, Raben A, Blundell JE, Astrup A: Reproducibility, power and validity of visual analogue scales in assessment of appetite sensations in single test meal studies. Int J Obes. 2000, 24: 38–48. 10.1038/sj.ijo.0801083.CrossRef Flint A, Raben A, Blundell JE, Astrup A: Reproducibility, power and validity of visual analogue scales in assessment of appetite sensations in single test meal studies. Int J Obes. 2000, 24: 38–48. 10.1038/sj.ijo.0801083.CrossRef
22.
go back to reference Greenhalf PL, Bodin K, Soderlund K, Hultman K: Effect of oral creatine supplementation on skeletal muscle phosphocreatine resynthesis. Am J Physiol. 1994, 266: 725–730. Greenhalf PL, Bodin K, Soderlund K, Hultman K: Effect of oral creatine supplementation on skeletal muscle phosphocreatine resynthesis. Am J Physiol. 1994, 266: 725–730.
23.
go back to reference Maresh CM, Armstrong LE, Hoffman JR, Hannon DR, Gabaree CL, Bergeron MF, Whittlesey MJ, Deschenes MR: Dietary supplementation and improved anaerobic test performance. Int J Sports Nutr. 1994, 4: 387–397.CrossRef Maresh CM, Armstrong LE, Hoffman JR, Hannon DR, Gabaree CL, Bergeron MF, Whittlesey MJ, Deschenes MR: Dietary supplementation and improved anaerobic test performance. Int J Sports Nutr. 1994, 4: 387–397.CrossRef
24.
go back to reference Syrotuik DG, Bell GJ: Acute creatine monohydrate supplementation: A descriptive physiological profile of responders vs. nonresponders. J Strength Cond Res. 2004, 18: 610–617. 10.1519/12392.1.PubMed Syrotuik DG, Bell GJ: Acute creatine monohydrate supplementation: A descriptive physiological profile of responders vs. nonresponders. J Strength Cond Res. 2004, 18: 610–617. 10.1519/12392.1.PubMed
25.
go back to reference Colker CM, Kalman DS, Torina GC, Perlis T, Street C: Effects of citrus aurantium extract, caffeine and St. John's wort on body fat loss, lipid levels, and mood states in overweight healthy adults. Curr Ther Res. 1999, 60: 145–153. 10.1016/S0011-393X(00)88523-9.CrossRef Colker CM, Kalman DS, Torina GC, Perlis T, Street C: Effects of citrus aurantium extract, caffeine and St. John's wort on body fat loss, lipid levels, and mood states in overweight healthy adults. Curr Ther Res. 1999, 60: 145–153. 10.1016/S0011-393X(00)88523-9.CrossRef
26.
go back to reference Ishihara K, Oyaizu S, Onuki K, Lim K, Fushiki T: Chronic (-)-hydroxycitrate administration spares carbohydrate utilization and promotes lipid oxidation during exercise in mice. J Nutr. 2000, 130: 2990–2995.CrossRef Ishihara K, Oyaizu S, Onuki K, Lim K, Fushiki T: Chronic (-)-hydroxycitrate administration spares carbohydrate utilization and promotes lipid oxidation during exercise in mice. J Nutr. 2000, 130: 2990–2995.CrossRef
27.
go back to reference Leonhardt M, Balkan B, Langhans W: Effect of hydroxycitrate on respiratory quotient, energy expenditure, and glucose tolerance in male rats after a period of restrictive feeding. Nutr. 2004, 20: 911–915. 10.1016/j.nut.2004.06.012.CrossRef Leonhardt M, Balkan B, Langhans W: Effect of hydroxycitrate on respiratory quotient, energy expenditure, and glucose tolerance in male rats after a period of restrictive feeding. Nutr. 2004, 20: 911–915. 10.1016/j.nut.2004.06.012.CrossRef
28.
go back to reference Graham TE, Hedge JW, MaClean DA, Kiens B, Richter EA: Caffeine ingestion does not alter carbohydrate or fat metabolism in human skeletal muscle during exercise. J Physiol. 2000, 529: 837–847. 10.1111/j.1469-7793.2000.00837.x.CrossRef Graham TE, Hedge JW, MaClean DA, Kiens B, Richter EA: Caffeine ingestion does not alter carbohydrate or fat metabolism in human skeletal muscle during exercise. J Physiol. 2000, 529: 837–847. 10.1111/j.1469-7793.2000.00837.x.CrossRef
29.
go back to reference Graham TE, Hibbert E, Sathasivam P: Metabolic and exercise endurance effects of coffee and caffeine ingestion. J Appl Physiol. 1998, 85: 883–889.CrossRef Graham TE, Hibbert E, Sathasivam P: Metabolic and exercise endurance effects of coffee and caffeine ingestion. J Appl Physiol. 1998, 85: 883–889.CrossRef
30.
go back to reference Mougios V, Ring S, Petridou A, Nikolaidis MG: Duration of coffee- and exercise-induced changes in the fatty acid profile of human serum. J Appl Physiol. 2003, 94: 476–484.CrossRef Mougios V, Ring S, Petridou A, Nikolaidis MG: Duration of coffee- and exercise-induced changes in the fatty acid profile of human serum. J Appl Physiol. 2003, 94: 476–484.CrossRef
31.
go back to reference Brown CM, McGrath JC, Midgley JM, Muir AG, O'Brien JW, Thonoor CM, Williams CM, Wilson VG: Activities of octopamine and synephrine stereoisomers on alpha-adrenoceptors. Br J Pharmacol. 1988, 93: 417–429.CrossRef Brown CM, McGrath JC, Midgley JM, Muir AG, O'Brien JW, Thonoor CM, Williams CM, Wilson VG: Activities of octopamine and synephrine stereoisomers on alpha-adrenoceptors. Br J Pharmacol. 1988, 93: 417–429.CrossRef
32.
go back to reference Noordzij M, Uiterwaal CS, Arends LR, Kok FJ, Grobbee DE, Geleijnse JM: Blood pressure response to chronic intake of coffee and caffeine: a meta-analysis of randomized controlled trials. J Hypertens. 2005, 23: 921–928. 10.1097/01.hjh.0000166828.94699.1d.CrossRef Noordzij M, Uiterwaal CS, Arends LR, Kok FJ, Grobbee DE, Geleijnse JM: Blood pressure response to chronic intake of coffee and caffeine: a meta-analysis of randomized controlled trials. J Hypertens. 2005, 23: 921–928. 10.1097/01.hjh.0000166828.94699.1d.CrossRef
33.
go back to reference Leiberman HR, Tharion WJ, Shukitt-Hale B, Speckman KL, Tulley R: Effects of caffeine, sleep loss, and stress on cognitive performance and mood during U.S. Navy SEAL training. Sea-Air-Land. Psychopharmacol. 2002, 164: 250–261. 10.1007/s00213-002-1217-9.CrossRef Leiberman HR, Tharion WJ, Shukitt-Hale B, Speckman KL, Tulley R: Effects of caffeine, sleep loss, and stress on cognitive performance and mood during U.S. Navy SEAL training. Sea-Air-Land. Psychopharmacol. 2002, 164: 250–261. 10.1007/s00213-002-1217-9.CrossRef
34.
go back to reference Smith A, Brice C, Nash J, Rich N, Nutt DJ: Caffeine and central noradrenaline: effects on mood, cognitive performance, eye movements and cardiovascular function. J Psycholpharmacol. 2003, 17: 283–292. 10.1177/02698811030173010.CrossRef Smith A, Brice C, Nash J, Rich N, Nutt DJ: Caffeine and central noradrenaline: effects on mood, cognitive performance, eye movements and cardiovascular function. J Psycholpharmacol. 2003, 17: 283–292. 10.1177/02698811030173010.CrossRef
Metadata
Title
Thermogenic Effect from Nutritionally Enriched Coffee Consumption
Authors
Jay R Hoffman
Jie Kang
Nicholas A Ratamess
Peter F Jennings
Gerald Mangine
Avery D Faigenbaum
Publication date
01-06-2006
Publisher
BioMed Central
DOI
https://doi.org/10.1186/1550-2783-3-1-35

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