Published in:
Open Access
01-07-2012 | Oral presentation
The effects of early aggressive therapy in JIA: results of the TREAT study
Authors:
Carol A Wallace, Edward H Giannini, Steven J Spalding, Philip J Hashkes, Kathleen M O’Neil, Andrew S Zeft, Ilona S Szer, Sarah M Ringold, Hermine Brunner, Laura E Schanberg, Robert P Sundel, Diana Milojevic, Marilynn G Punaro, Peter Chira, Beth S Gottlieb, Gloria C Higgins, Norman T Ilowite, Yukiko Kimura, Bin Huang, Daniel J Lovell
Published in:
Pediatric Rheumatology
|
Special Issue 1/2012
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Excerpt
Early aggressive therapy has been shown to result in superior outcomes in adults with RA, but evidence for a similar benefit has not been demonstrated in children with JIA. The objective was to determine if aggressive treatment initiated within the first 12 mos after onset of extended oligoarticular (e-oligo), or RF + or (-) polyarticular JIA (poly JIA) can induce inactive disease (ID) within 6 mos (primary endpoint) and clinical remission on medication (CRM: ID for 6 continuous mos on medication; exploratory endpoint) within 1 yr of starting therapy. …
