Published in:
Open Access
01-07-2012 | Poster presentation
Evidence of fibrinogen as a target of citrullination in IgM rheumatoid factor-positive polyarticular juvenile idiopathic arthritis
Authors:
Brooke E Gilliam, Melinda R Reed, Anil K Chauhan, Amanda Dehlendorf, Peri H Pepmueller, Terry L Moore
Published in:
Pediatric Rheumatology
|
Special Issue 1/2012
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Excerpt
The role of anti-cyclic citrullinated peptide (anti-CCP) antibodies in juvenile idiopathic arthritis (JIA) has become better understood; however, the identity of the target proteins of this modification remains elusive. We evaluated serum from patients with various subtypes of JIA to investigate the presence of anti-citrullinated fibrinogen and anti-citrullinated α-enolase antibodies, and their association with rheumatoid factor (RF) and anti-CCP antibodies. …