Published in:
Open Access
01-11-2010 | Poster presentation
TLR signals modify the expression of scavenger receptors
Authors:
C Zamora, E Cantó, J C Nieto, C Juarez, S Vidal
Published in:
Journal of Translational Medicine
|
Special Issue 1/2010
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Excerpt
Toll like receptors (TLRs) and scavenger receptors are expressed on the surface of monocytes in order to participate in relevant innate immune functions. It has been established that TLRs can discriminate molecular structures normally absent in the healthy host, whereas CD36 is a class B scavenger receptor that can coordinate responses to TLR2:TLR6 agonists. Although recent studies have focused on CD36-TLR cooperation in mediating phagocytosis, it is not know whether TLRs can regulate the expression of scavenger receptors. …