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Published in: Journal of Translational Medicine 1/2010

Open Access 01-11-2010 | Poster presentation

Certolizumab pegol has a different profile from other anti-TNFs, including golimumab, in a variety of in vitro assays

Authors: G Fossati, A Nesbitt

Published in: Journal of Translational Medicine | Special Issue 1/2010

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Excerpt

Differences in structure and in vitro properties of anti-TNF agents may account for different modes of action and clinical outcomes. The activities of certolizumab pegol (CZP), etanercept (ETA), infliximab (IFX) and adalimumab (ADA) have been compared using in vitro assays. [1] However, golimumab (GLM) has not previously been evaluated. …
Literature
1.
go back to reference Nesbitt A, Fossati G, Bergin M, Stephens P, Stephens S, Foulkes R, Brown D, Robinson M, Bourne T: Mechanism of action of certolizumab pegol (CDP870): In vitro comparison with other anti-tumor necrosis factor alpha agents. Inflamm Bowel Dis. 2007, 13: 1323-1332. 10.1002/ibd.20225.CrossRefPubMed Nesbitt A, Fossati G, Bergin M, Stephens P, Stephens S, Foulkes R, Brown D, Robinson M, Bourne T: Mechanism of action of certolizumab pegol (CDP870): In vitro comparison with other anti-tumor necrosis factor alpha agents. Inflamm Bowel Dis. 2007, 13: 1323-1332. 10.1002/ibd.20225.CrossRefPubMed
Metadata
Title
Certolizumab pegol has a different profile from other anti-TNFs, including golimumab, in a variety of in vitro assays
Authors
G Fossati
A Nesbitt
Publication date
01-11-2010
Publisher
BioMed Central
Published in
Journal of Translational Medicine / Issue Special Issue 1/2010
Electronic ISSN: 1479-5876
DOI
https://doi.org/10.1186/1479-5876-8-S1-P37

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