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Journal of Translational Medicine
Published in: Journal of Translational Medicine 1/2010

Open Access 01-11-2010 | Poster presentation

Cocoa diet diminishes the anti-collagen humoral response in collagen-induced arthritis in rats

Authors: S Ramos-Romero, T Pérez-Berezo, F J Pérez-Cano, C Castellote, M Castell, A Franch

Published in: Journal of Translational Medicine | Special Issue 1/2010

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Excerpt

Collagen type II-induced arthritis (CIA) shares immunological and pathological characteristics with human rheumatoid arthritis. Anti-collagen (CII) autoantibodies appear to be a primary mechanism of immunopathogenesis in this model [1]. On the other hand, previous studies have shown that rats fed cocoa exhibit a lower antibody production after ovoalbumin immunization [2]. …
Literature
1.
Holmdahl R, Lorentzen JC, Lu S, Olofsson P, Wester L, Holmberg J, Pettersson U: Arthritis induced in rats with non-immunogenic adjuvants as models for rheumatoid arthritis. Immunol Rev. 2001, 184: 184-202. 10.1034/j.1600-065x.2001.1840117.x.CrossRefPubMed
2.
Pérez-Berezo T, Ramiro-Puig E, Pérez-Cano FJ, Castellote C, Permanyer J, Franch A, Castell M: Influence of a cocoa-enriched diet on specific immune response in ovalbumin-sensitized rats. Mol Nutr Food Res. 2009, 53: 389-397. 10.1002/mnfr.200700396.CrossRefPubMed
Metadata
Title
Cocoa diet diminishes the anti-collagen humoral response in collagen-induced arthritis in rats
Authors
S Ramos-Romero
T Pérez-Berezo
F J Pérez-Cano
C Castellote
M Castell
A Franch
Publication date
01-11-2010
Publisher
BioMed Central
Published in
Journal of Translational Medicine / Issue Special Issue 1/2010
Electronic ISSN: 1479-5876
DOI
https://doi.org/10.1186/1479-5876-8-S1-P25

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