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Published in: Journal of Translational Medicine 1/2014

Open Access 01-05-2014 | Poster presentation

Barasertib: a novel approach for the treatment of metastatic melanoma

Authors: Amalia Azzariti, Letizia Porcelli, Anna Elisa Quatrale, Letizia Sidella, RM Iacobazzi, Gabriella Guida, Immacolata Maida, Tiziana Cocco, Anna Ferretta, Sabino Strippoli, Stefania Giuda, Stefani Tommasi, Angelo Paradiso, Michele Guida

Published in: Journal of Translational Medicine | Special Issue 1/2014

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Excerpt

Metastatic melanoma represents the most deadly form of skin cancer. The poor response to chemotherapy and the brief response to the anti-BRAF vemurafenib in selected population of patients, make the identification of new therapeutic approaches an urgent need. Our goal is the evaluation of the efficacy of barasertib, an aurora B kinase inhibitor impairing cytokinesis, in both mutated and non-mutated melanoma cell lines. …
Metadata
Title
Barasertib: a novel approach for the treatment of metastatic melanoma
Authors
Amalia Azzariti
Letizia Porcelli
Anna Elisa Quatrale
Letizia Sidella
RM Iacobazzi
Gabriella Guida
Immacolata Maida
Tiziana Cocco
Anna Ferretta
Sabino Strippoli
Stefania Giuda
Stefani Tommasi
Angelo Paradiso
Michele Guida
Publication date
01-05-2014
Publisher
BioMed Central
Published in
Journal of Translational Medicine / Issue Special Issue 1/2014
Electronic ISSN: 1479-5876
DOI
https://doi.org/10.1186/1479-5876-12-S1-P7

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