Skip to main content
Top
Published in: Cost Effectiveness and Resource Allocation 1/2013

Open Access 01-12-2013 | Research

Protecting child health and nutrition status with ready-to-use food in addition to food assistance in urban Chad: a cost-effectiveness analysis

Authors: Chloe Puett, Cécile Salpéteur, Elisabeth Lacroix, Freddy Houngbé, Myriam Aït-Aïssa, Anne-Dominique Israël

Published in: Cost Effectiveness and Resource Allocation | Issue 1/2013

Login to get access

Abstract

Background

Despite growing interest in use of lipid nutrient supplements for preventing child malnutrition and morbidity, there is inconclusive evidence on the effectiveness, and no evidence on the cost-effectiveness of this strategy.

Methods

A cost effectiveness analysis was conducted comparing costs and outcomes of two arms of a cluster randomized controlled trial implemented in eastern Chad during the 2010 hunger gap by Action contre la Faim France and Ghent University. This trial assessed the effect on child malnutrition and morbidity of a 5-month general distribution of staple rations, or staple rations plus a ready-to-use supplementary food (RUSF). RUSF was distributed to households with a child aged 6–36 months who was not acutely malnourished (weight-for-height > = 80% of the NCHS reference median, and absence of bilateral pitting edema), to prevent acute malnutrition in these children. While the addition of RUSF to a staple ration did not result in significant reduction in wasting rates, cost-effectiveness was assessed using successful secondary outcomes of cases of diarrhea and anemia (hemoglobin <110 g/L) averted among children receiving RUSF.
Total costs of the program and incremental costs of RUSF and related management and logistics were estimated using accounting records and key informant interviews, and include costs to institutions and communities. An activity-based costing methodology was applied and incremental costs were calculated per episode of diarrhea and case of anemia averted.

Results

Adding RUSF to a general food distribution increased total costs by 23%, resulting in an additional cost per child of 374 EUR, and an incremental cost per episode of diarrhea averted of 1,083 EUR and per case of anemia averted of 3,627 EUR.

Conclusions

Adding RUSF to a staple ration was less cost-effective than other standard intervention options for averting diarrhea and anemia. This strategy holds potential to address a broad array of health and nutrition outcomes in emergency settings where infrastructure is weak and other intervention options are infeasible in the short-term. However, further research is needed to establish the contexts in which RUSF is most effective and cost-effective in preventing acute malnutrition and morbidity among vulnerable children, compared to other options.
Appendix
Available only for authorised users
Literature
1.
go back to reference Diop E, Dossou N, Ndour M, Briend A, Wade S: Comparison of the efficacy of a solid ready-to-use food and a liquid, milk-based diet for the rehabilitation of severely malnourished children: a randomized trial. Am J Clin Nutr 2003, 78: 302–307. Diop E, Dossou N, Ndour M, Briend A, Wade S: Comparison of the efficacy of a solid ready-to-use food and a liquid, milk-based diet for the rehabilitation of severely malnourished children: a randomized trial. Am J Clin Nutr 2003, 78: 302–307.
2.
go back to reference Manary MJ, Ndekha M, Ashorn P, Maleta K, Briend A: Home based therapy for severe malnutrition with ready-to-use food. Arch Dis Child 2004, 89: 557–561.PubMedCentralCrossRefPubMed Manary MJ, Ndekha M, Ashorn P, Maleta K, Briend A: Home based therapy for severe malnutrition with ready-to-use food. Arch Dis Child 2004, 89: 557–561.PubMedCentralCrossRefPubMed
3.
go back to reference Collins S, Dent N, Binns P, Bahwere P, Sadler K, Hallam A: Management of severe acute malnutrition in children. Lancet 2006, 368: 1992–2000.CrossRefPubMed Collins S, Dent N, Binns P, Bahwere P, Sadler K, Hallam A: Management of severe acute malnutrition in children. Lancet 2006, 368: 1992–2000.CrossRefPubMed
4.
go back to reference Chaparro CM, Dewey KG: Use of lipid-based nutrient supplements (LNS) to improve the nutrient adequacy of general food distribution rations for vulnerable sub-groups in emergency settings. Matern Child Nutr 2010, 6: 1–69.CrossRefPubMed Chaparro CM, Dewey KG: Use of lipid-based nutrient supplements (LNS) to improve the nutrient adequacy of general food distribution rations for vulnerable sub-groups in emergency settings. Matern Child Nutr 2010, 6: 1–69.CrossRefPubMed
5.
go back to reference Dewey KG, Adu-Afarwuah S: Systematic review of the efficacy and effectiveness of complementary feeding interventions in developing countries. Matern Child Nutr 2008, 4: 24–85.CrossRefPubMed Dewey KG, Adu-Afarwuah S: Systematic review of the efficacy and effectiveness of complementary feeding interventions in developing countries. Matern Child Nutr 2008, 4: 24–85.CrossRefPubMed
6.
go back to reference Isanaka S, Nombela N, Djibo A, Poupard M, Van Beckhoven D, Gaboulaud V, Guerin PJ, Grais RF: Effect of preventive supplementation with ready-to-use therapeutic food on the nutritional status, mortality, and morbidity of children aged 6 to 60 months in Niger a cluster randomized trial. JAMA 2009, 301: 277–285.PubMedCentralCrossRefPubMed Isanaka S, Nombela N, Djibo A, Poupard M, Van Beckhoven D, Gaboulaud V, Guerin PJ, Grais RF: Effect of preventive supplementation with ready-to-use therapeutic food on the nutritional status, mortality, and morbidity of children aged 6 to 60 months in Niger a cluster randomized trial. JAMA 2009, 301: 277–285.PubMedCentralCrossRefPubMed
7.
go back to reference Defourny I, Minetti A, Harczi G, Doyon S, Shepard S, Tectonidis M, Bradol J-H, Golden M: A large-scale distribution of milk-based fortified spreads: evidence for a new approach in regions with high burden of acute malnutrition. PLoS ONE 2009, 4: e5455.PubMedCentralCrossRefPubMed Defourny I, Minetti A, Harczi G, Doyon S, Shepard S, Tectonidis M, Bradol J-H, Golden M: A large-scale distribution of milk-based fortified spreads: evidence for a new approach in regions with high burden of acute malnutrition. PLoS ONE 2009, 4: e5455.PubMedCentralCrossRefPubMed
8.
go back to reference Matilsky D, Maleta K, Castleman T, Manary M: Supplementary feeding with fortified spreads results in higher recovery rates than with a corn/soy blend in moderately wasted children. J Nutr 2009, 139: 773–778.PubMedCentralCrossRefPubMed Matilsky D, Maleta K, Castleman T, Manary M: Supplementary feeding with fortified spreads results in higher recovery rates than with a corn/soy blend in moderately wasted children. J Nutr 2009, 139: 773–778.PubMedCentralCrossRefPubMed
9.
go back to reference Nackers F, Broillet F, Oumarou D, Djibo A, Gaboulaud V, Guerin PJ, Rusch B, Grais RF, Captier V: Effectiveness of ready-to-use therapeutic food compared to a corn/soy-blend-based pre-mix for the treatment of childhood moderate acute malnutrition in Niger. J Trop Pediatr 2010, 56: 407–413.CrossRefPubMed Nackers F, Broillet F, Oumarou D, Djibo A, Gaboulaud V, Guerin PJ, Rusch B, Grais RF, Captier V: Effectiveness of ready-to-use therapeutic food compared to a corn/soy-blend-based pre-mix for the treatment of childhood moderate acute malnutrition in Niger. J Trop Pediatr 2010, 56: 407–413.CrossRefPubMed
10.
go back to reference Patel MP, Sandige HL, Ndekha MJ, Briend A, Ashorn P, Manary MJ: Supplemental feeding with ready-to-use therapeutic food in Malawian children at risk of malnutrition. J Health Popul Nutr 2005, 23: 351–357.PubMed Patel MP, Sandige HL, Ndekha MJ, Briend A, Ashorn P, Manary MJ: Supplemental feeding with ready-to-use therapeutic food in Malawian children at risk of malnutrition. J Health Popul Nutr 2005, 23: 351–357.PubMed
11.
go back to reference Talley L, Boyd E, El Sharief F, Blanton C, Ali MO, El Rahman MMOA: Prevention of acute malnutrition during the lean season: comparison of a lipid-based nutrient supplement and an improved dry ration, south Darfur, Sudan, a quasi-experimental study. Nutr Disord Therapy 2012, 2: 117. Talley L, Boyd E, El Sharief F, Blanton C, Ali MO, El Rahman MMOA: Prevention of acute malnutrition during the lean season: comparison of a lipid-based nutrient supplement and an improved dry ration, south Darfur, Sudan, a quasi-experimental study. Nutr Disord Therapy 2012, 2: 117.
12.
go back to reference Karakochuk C, Van den Briel T, Stephens D, Zlotkin S: Treatment of moderate acute malnutrition with ready-to-use supplementary food results in higher overall recovery rates compared with corn-soya blend in children in southern Ethiopia: an operations research trial. Am J Clin Nutr 2012, 96: 911–916.CrossRefPubMed Karakochuk C, Van den Briel T, Stephens D, Zlotkin S: Treatment of moderate acute malnutrition with ready-to-use supplementary food results in higher overall recovery rates compared with corn-soya blend in children in southern Ethiopia: an operations research trial. Am J Clin Nutr 2012, 96: 911–916.CrossRefPubMed
13.
go back to reference LaGrone LN, Trehan I, Meuli GJ, Wang RJ, Thakwalakwa C, Maleta K, Manary MJ: A novel fortified blended flour, corn-soy blend “plus-plus”, is not inferior to lipid-based ready-to-use supplementary foods for the treatment of moderate acute malnutrition in Malawian children. Am J Clin Nutr 2012, 95: 212–219.PubMedCentralCrossRefPubMed LaGrone LN, Trehan I, Meuli GJ, Wang RJ, Thakwalakwa C, Maleta K, Manary MJ: A novel fortified blended flour, corn-soy blend “plus-plus”, is not inferior to lipid-based ready-to-use supplementary foods for the treatment of moderate acute malnutrition in Malawian children. Am J Clin Nutr 2012, 95: 212–219.PubMedCentralCrossRefPubMed
14.
go back to reference Kuusipalo H, Maleta K, Briend A, Manary MJ, Ashorn P: Growth and change in blood haemoglobin concentration among underweight Malawian infants receiving fortified spreads for 12 weeks: a preliminary trial. J Pediatr Gastroenterol Nutr 2006, 43: 525–532.CrossRefPubMed Kuusipalo H, Maleta K, Briend A, Manary MJ, Ashorn P: Growth and change in blood haemoglobin concentration among underweight Malawian infants receiving fortified spreads for 12 weeks: a preliminary trial. J Pediatr Gastroenterol Nutr 2006, 43: 525–532.CrossRefPubMed
15.
go back to reference Adu-Afarwuah S, Lartey A, Brown KH, Zlotkin S, Briend A, Dewey KG: Randomized comparison of 3 types of micronutrient supplements for home fortification of complementary foods in Ghana: effects on growth and motor development. Am J Clin Nutr 2007, 86: 412–420.PubMed Adu-Afarwuah S, Lartey A, Brown KH, Zlotkin S, Briend A, Dewey KG: Randomized comparison of 3 types of micronutrient supplements for home fortification of complementary foods in Ghana: effects on growth and motor development. Am J Clin Nutr 2007, 86: 412–420.PubMed
16.
go back to reference Lopriore C, Guidoum Y, Briend A, Branca F: Spread fortified with vitamins and minerals induces catch-up growth and eradicates severe anemia in stunted refugee children aged 3–6 y. Am J Clin Nutr 2004, 80: 973–981.PubMed Lopriore C, Guidoum Y, Briend A, Branca F: Spread fortified with vitamins and minerals induces catch-up growth and eradicates severe anemia in stunted refugee children aged 3–6 y. Am J Clin Nutr 2004, 80: 973–981.PubMed
17.
go back to reference Isanaka S, Roederer T, Djibo A, Luquero FJ, Nombela N, Guerin PJ, Grais RF: Reducing wasting in young children with preventive supplementation: a cohort study in Niger. Pediatrics 2010, 126: E442-E450.PubMedCentralCrossRefPubMed Isanaka S, Roederer T, Djibo A, Luquero FJ, Nombela N, Guerin PJ, Grais RF: Reducing wasting in young children with preventive supplementation: a cohort study in Niger. Pediatrics 2010, 126: E442-E450.PubMedCentralCrossRefPubMed
18.
go back to reference Huybregts L, Houngbé F, Salpéteur C, Brown R, Roberfroid D, Ait-Aissa M, Kolsteren P: The effect of adding ready-to-use supplementary food to a general food distribution on child nutritional status and morbidity: a cluster randomized controlled trial. PLoS Med 2012, 9: e1001313.PubMedCentralCrossRefPubMed Huybregts L, Houngbé F, Salpéteur C, Brown R, Roberfroid D, Ait-Aissa M, Kolsteren P: The effect of adding ready-to-use supplementary food to a general food distribution on child nutritional status and morbidity: a cluster randomized controlled trial. PLoS Med 2012, 9: e1001313.PubMedCentralCrossRefPubMed
19.
go back to reference Phuka JC, Maleta K, Thakwalakwa C, Cheung YB, Briend A, Manary MJ, Ashorn P: Complementary feeding with fortified spread and incidence of severe stunting in 6- to 18-month-old rural Malawians. Arch Pediatr Adolesc Med 2008, 162: 619.PubMedCentralCrossRefPubMed Phuka JC, Maleta K, Thakwalakwa C, Cheung YB, Briend A, Manary MJ, Ashorn P: Complementary feeding with fortified spread and incidence of severe stunting in 6- to 18-month-old rural Malawians. Arch Pediatr Adolesc Med 2008, 162: 619.PubMedCentralCrossRefPubMed
20.
go back to reference Grellety E, Shepherd S, Roederer T, Manzo ML, Doyon S, Ategbo E-A, Grais RF: Effect of mass supplementation with ready-to-use supplementary food during an anticipated nutritional emergency. PLoS ONE 2012, 7: e44549.PubMedCentralCrossRefPubMed Grellety E, Shepherd S, Roederer T, Manzo ML, Doyon S, Ategbo E-A, Grais RF: Effect of mass supplementation with ready-to-use supplementary food during an anticipated nutritional emergency. PLoS ONE 2012, 7: e44549.PubMedCentralCrossRefPubMed
21.
go back to reference Maleta K, Kuittinen J, Duggan MB, Briend A, Manary MJ, Wales J, Kulmala T, Ashorn P: Supplementary feeding of underweight, stunted Malawian children with a ready-to-use food. J Pediatr Gastroenterol Nutr 2004, 38: 152–158.CrossRefPubMed Maleta K, Kuittinen J, Duggan MB, Briend A, Manary MJ, Wales J, Kulmala T, Ashorn P: Supplementary feeding of underweight, stunted Malawian children with a ready-to-use food. J Pediatr Gastroenterol Nutr 2004, 38: 152–158.CrossRefPubMed
22.
go back to reference Mangani C, Maleta K, Phuka J, Cheung YB, Thakwalakwa C, Dewey K, Manary M, Puumalainen T, Ashorn P: Effect of complementary feeding with lipid-based nutrient supplements and corn-soy blend on the incidence of stunting and linear growth among 6- to 18-month-old infants and children in Malawi. Matern Child Nutr 2013. Advance online publication. doi: 10.1111/mcn.12068 Mangani C, Maleta K, Phuka J, Cheung YB, Thakwalakwa C, Dewey K, Manary M, Puumalainen T, Ashorn P: Effect of complementary feeding with lipid-based nutrient supplements and corn-soy blend on the incidence of stunting and linear growth among 6- to 18-month-old infants and children in Malawi. Matern Child Nutr 2013. Advance online publication. doi: 10.1111/mcn.12068
23.
go back to reference Ciliberto MA, Sandige H, Ndekha MJ, Ashorn P, Briend A, Ciliberto HM, Manary MJ: Comparison of home-based therapy with ready-to-use therapeutic food with standard therapy in the treatment of malnourished Malawian children: a controlled, clinical effectiveness trial. Am J Clin Nutr 2005, 81: 864–870.PubMed Ciliberto MA, Sandige H, Ndekha MJ, Ashorn P, Briend A, Ciliberto HM, Manary MJ: Comparison of home-based therapy with ready-to-use therapeutic food with standard therapy in the treatment of malnourished Malawian children: a controlled, clinical effectiveness trial. Am J Clin Nutr 2005, 81: 864–870.PubMed
24.
go back to reference Queiroz V, Assis A, Pinheiro S, Ribeiro Junior H: Predictors of linear growth in the first year of life of a prospective cohort of full term children with normal birth weight. J Pediatr (Rio J) 2012, 88: 79–86.CrossRef Queiroz V, Assis A, Pinheiro S, Ribeiro Junior H: Predictors of linear growth in the first year of life of a prospective cohort of full term children with normal birth weight. J Pediatr (Rio J) 2012, 88: 79–86.CrossRef
25.
go back to reference Ruel MT, Menon P: Child feeding practices are associated with child nutritional status in Latin America: innovative uses of the demographic and health surveys. J Nutr 2002, 132: 1180–1187.PubMed Ruel MT, Menon P: Child feeding practices are associated with child nutritional status in Latin America: innovative uses of the demographic and health surveys. J Nutr 2002, 132: 1180–1187.PubMed
26.
go back to reference Lutter C, Rodriguez A, Fuenmayor G, Avila L, Sempertegui F, Escobar J: Growth and micronutrient status in children receiving a fortified complementary food. J Nutr 2008, 138: 379–388.CrossRefPubMed Lutter C, Rodriguez A, Fuenmayor G, Avila L, Sempertegui F, Escobar J: Growth and micronutrient status in children receiving a fortified complementary food. J Nutr 2008, 138: 379–388.CrossRefPubMed
27.
go back to reference Fewtrell MS, Morley R, Abbott RA, Singhal A, Stephenson T, MacFadyen UM, Clements H, Lucas A: Catch-up growth in small-for-gestational-age term infants: a randomized trial. J Nutr 2001, 74: 516–523. Fewtrell MS, Morley R, Abbott RA, Singhal A, Stephenson T, MacFadyen UM, Clements H, Lucas A: Catch-up growth in small-for-gestational-age term infants: a randomized trial. J Nutr 2001, 74: 516–523.
28.
go back to reference Lawless JW, Latham MC, Stephenson LS, Kinoti SN, Pertet AM: Iron supplementation improves appetite and growth in anemic Kenyan primary school children. J Nutr 1994, 124: 645–654.PubMed Lawless JW, Latham MC, Stephenson LS, Kinoti SN, Pertet AM: Iron supplementation improves appetite and growth in anemic Kenyan primary school children. J Nutr 1994, 124: 645–654.PubMed
29.
go back to reference Mozaffari-Khosravi H, Shakiba M, Eftekhari M-H, Fatehi F: Effects of zinc supplementation on physical growth in 2–5-year-old children. Biol Trace Elem Res 2009, 128: 118–127.CrossRefPubMed Mozaffari-Khosravi H, Shakiba M, Eftekhari M-H, Fatehi F: Effects of zinc supplementation on physical growth in 2–5-year-old children. Biol Trace Elem Res 2009, 128: 118–127.CrossRefPubMed
30.
go back to reference UNICEF: UNICEF Humanitarian Action 2010: Mid-year review. New York: UNICEF; 2010. UNICEF: UNICEF Humanitarian Action 2010: Mid-year review. New York: UNICEF; 2010.
31.
go back to reference Health and Nutrition Tracking Service: Tchad Analyse Mars 2011. Geneva: World Health Organization; 2011. Health and Nutrition Tracking Service: Tchad Analyse Mars 2011. Geneva: World Health Organization; 2011.
32.
go back to reference Action Contre la Faim–France: Enquête anthropométrique nutritionnelle et de la mortalité Enfants âgés de 6 à 59 mois, Abeche ville, Département de Ouarra, Région du Ouaddaï. Paris: Action Contre la Faim–France; 2009. Action Contre la Faim–France: Enquête anthropométrique nutritionnelle et de la mortalité Enfants âgés de 6 à 59 mois, Abeche ville, Département de Ouarra, Région du Ouaddaï. Paris: Action Contre la Faim–France; 2009.
33.
go back to reference Action Contre la Faim–France: Enquête anthropométrique nutritionnelle et de la mortalité rétrospective à Abeche ville, Département de Ouarra, Région du Ouaddaï, Tchad, Janvier 2010. Paris: Action Contre la Faim–France; 2010. Action Contre la Faim–France: Enquête anthropométrique nutritionnelle et de la mortalité rétrospective à Abeche ville, Département de Ouarra, Région du Ouaddaï, Tchad, Janvier 2010. Paris: Action Contre la Faim–France; 2010.
34.
go back to reference WHO, UNHCR, IFRC, WFP: The management of nutrition in major emergencies. Geneva: World Health Organization; 2000. WHO, UNHCR, IFRC, WFP: The management of nutrition in major emergencies. Geneva: World Health Organization; 2000.
35.
go back to reference Action Contre la Faim–France: Activity Progress Report. Chad, September 2010. Paris: Action Contre la Faim–France; 2010. Action Contre la Faim–France: Activity Progress Report. Chad, September 2010. Paris: Action Contre la Faim–France; 2010.
36.
go back to reference Tan-Torres Edejer T, Baltussen R, Adam T, Hutubessy R, Acharya A, Evans D, Murray C: Making Choices in Health: WHO Guide to Cost- Effectiveness Analysis. Geneva: WHO; 2003. Tan-Torres Edejer T, Baltussen R, Adam T, Hutubessy R, Acharya A, Evans D, Murray C: Making Choices in Health: WHO Guide to Cost- Effectiveness Analysis. Geneva: WHO; 2003.
37.
go back to reference Fiedler JL, Villalobos CA, De Mattos AC: An activity-based cost analysis of the Honduras community-based, integrated child care (AIN-C) programme. Health Policy Plan 2008, 23: 408–427.CrossRefPubMed Fiedler JL, Villalobos CA, De Mattos AC: An activity-based cost analysis of the Honduras community-based, integrated child care (AIN-C) programme. Health Policy Plan 2008, 23: 408–427.CrossRefPubMed
38.
go back to reference Takimoto A, Ramachandran Nair PK, Alavalapati JRR: Socioeconomic potential of carbon sequestration through agroforestry in the West African Sahel. Mitig Adapt Strat Glob Chang 2008, 13: 745–761.CrossRef Takimoto A, Ramachandran Nair PK, Alavalapati JRR: Socioeconomic potential of carbon sequestration through agroforestry in the West African Sahel. Mitig Adapt Strat Glob Chang 2008, 13: 745–761.CrossRef
39.
go back to reference Mason NM, Ricker-Gilbert J: Disrupting demand for commercial seed: Input subsidies in Malawi and Zambia. Lusaka, Zambia: Indaba Agricultural Policy Research Institute (IAPRI); 2012. Mason NM, Ricker-Gilbert J: Disrupting demand for commercial seed: Input subsidies in Malawi and Zambia. Lusaka, Zambia: Indaba Agricultural Policy Research Institute (IAPRI); 2012.
40.
go back to reference Afari-Sefa V, Gockowski J, Agyeman NF, Dziwornu AK: Economic cost-benefit analysis of certified sustainable cocoa production in Ghana. Accra, Ghana: International Institute of Tropical Agriculture (IITA); 2010. Afari-Sefa V, Gockowski J, Agyeman NF, Dziwornu AK: Economic cost-benefit analysis of certified sustainable cocoa production in Ghana. Accra, Ghana: International Institute of Tropical Agriculture (IITA); 2010.
41.
go back to reference Microsoft: Microsoft Excel. Redmond: Microsoft; 2007. Microsoft: Microsoft Excel. Redmond: Microsoft; 2007.
42.
go back to reference TreeAge: TreeAge Pro Healthcare. Williamstown: TreeAge; 2012. TreeAge: TreeAge Pro Healthcare. Williamstown: TreeAge; 2012.
43.
go back to reference Drummond MF, Sculpher MJ, Torrance GW, O’Brien BJ, Stoddart GL: Methods for the economic evaluation of health care progammes. Third. New York: Oxford University Press; 2005. Drummond MF, Sculpher MJ, Torrance GW, O’Brien BJ, Stoddart GL: Methods for the economic evaluation of health care progammes. Third. New York: Oxford University Press; 2005.
44.
go back to reference Sandige HL, Ndekha MJ, Briend A, Ashorn P, Manary MJ: Home-based treatment of malnourished Malawian children with locally produced or imported ready-to-use food. J Pediatr Gastroenterol Nutr 2004, 39: 141–146.CrossRefPubMed Sandige HL, Ndekha MJ, Briend A, Ashorn P, Manary MJ: Home-based treatment of malnourished Malawian children with locally produced or imported ready-to-use food. J Pediatr Gastroenterol Nutr 2004, 39: 141–146.CrossRefPubMed
45.
go back to reference Komrska J: Increasing access to ready-to-use therapeutic foods (RUTF). Field Exch 2012, 42: 46–47. Komrska J: Increasing access to ready-to-use therapeutic foods (RUTF). Field Exch 2012, 42: 46–47.
46.
go back to reference Segrè J, Winnard K, Abrha TH, Abebe Y, Shilane D, Lapping K: Willingness to pay for lipid-based nutrient supplements for young children in four urban sites of Ethiopia. Matern Child Nutr 2012. Advance online publication. doi: 10.1111/mcn.12022 Segrè J, Winnard K, Abrha TH, Abebe Y, Shilane D, Lapping K: Willingness to pay for lipid-based nutrient supplements for young children in four urban sites of Ethiopia. Matern Child Nutr 2012. Advance online publication. doi: 10.1111/mcn.12022
47.
go back to reference Bachmann MO: Cost effectiveness of community-based therapeutic care for children with severe acute malnutrition in Zambia: decision tree model. Cost Effectiveness and Resource Allocation 2009, 7: 2.PubMedCentralCrossRefPubMed Bachmann MO: Cost effectiveness of community-based therapeutic care for children with severe acute malnutrition in Zambia: decision tree model. Cost Effectiveness and Resource Allocation 2009, 7: 2.PubMedCentralCrossRefPubMed
48.
go back to reference Wilford R, Golden K, Walker DG: Cost-effectiveness of community-based management of acute malnutrition in Malawi. Health Policy Plan 2012, 27: 127–37.CrossRefPubMed Wilford R, Golden K, Walker DG: Cost-effectiveness of community-based management of acute malnutrition in Malawi. Health Policy Plan 2012, 27: 127–37.CrossRefPubMed
49.
go back to reference Tekeste A, Wondafrash M, Azene G, Deribe K: Cost effectiveness of community-based and in-patient therapeutic feeding programs to treat severe acute malnutrition in Ethiopia. Cost Effectiveness and Resource Allocation 2012, 10: 4.PubMedCentralCrossRefPubMed Tekeste A, Wondafrash M, Azene G, Deribe K: Cost effectiveness of community-based and in-patient therapeutic feeding programs to treat severe acute malnutrition in Ethiopia. Cost Effectiveness and Resource Allocation 2012, 10: 4.PubMedCentralCrossRefPubMed
50.
go back to reference Puett C, Sadler K, Alderman H, Coates J, Fiedler JL, Myatt M: Cost-effectiveness of the community-based management of severe acute malnutrition by community health workers in southern Bangladesh. Health Policy Plan 2013, 28: 386–399.CrossRefPubMed Puett C, Sadler K, Alderman H, Coates J, Fiedler JL, Myatt M: Cost-effectiveness of the community-based management of severe acute malnutrition by community health workers in southern Bangladesh. Health Policy Plan 2013, 28: 386–399.CrossRefPubMed
51.
go back to reference Horton S, Ross J: The economics of iron deficiency. Food Policy 2003, 28: 51–75.CrossRef Horton S, Ross J: The economics of iron deficiency. Food Policy 2003, 28: 51–75.CrossRef
52.
go back to reference Jamison D, Breman J, Measham A, Alleyne G, Claeson M, Evans D, Jha P, Mills A, Musgrove P: Disease Control Priorities in Developing Countries. New York: Oxford University Press; 2006. Jamison D, Breman J, Measham A, Alleyne G, Claeson M, Evans D, Jha P, Mills A, Musgrove P: Disease Control Priorities in Developing Countries. New York: Oxford University Press; 2006.
53.
go back to reference Alderman H, Horton SE: The economics of addressing nutritional anemia. In Nutritional Anemia. Edited by: Kraemer K, Zimmerman MB. Basel: Sight and Life Press; 2007:19–35. Alderman H, Horton SE: The economics of addressing nutritional anemia. In Nutritional Anemia. Edited by: Kraemer K, Zimmerman MB. Basel: Sight and Life Press; 2007:19–35.
54.
go back to reference Baltussen R, Knai C, Sharan M: Iron fortification and iron supplementation are cost-effective interventions to reduce iron deficiency in four subregions of the world. J Nutr 2004, 134: 2678–2684.PubMed Baltussen R, Knai C, Sharan M: Iron fortification and iron supplementation are cost-effective interventions to reduce iron deficiency in four subregions of the world. J Nutr 2004, 134: 2678–2684.PubMed
55.
go back to reference Commission on Macroeconomics and Health: Macroeconomics and health: Investing in health for economic development. Geneva: WHO; 2001. Commission on Macroeconomics and Health: Macroeconomics and health: Investing in health for economic development. Geneva: WHO; 2001.
56.
go back to reference Sharieff W, Bhutta Z, Tomlinson G, Zlotkin S: Micronutrients (including zinc) reduce diarrhoea in children: The Pakistan Sprinkles Diarrhoea Study. Arch Dis Child 2006, 91: 573–579.PubMedCentralCrossRefPubMed Sharieff W, Bhutta Z, Tomlinson G, Zlotkin S: Micronutrients (including zinc) reduce diarrhoea in children: The Pakistan Sprinkles Diarrhoea Study. Arch Dis Child 2006, 91: 573–579.PubMedCentralCrossRefPubMed
57.
go back to reference Giovannini M, Sala D, Usuelli M, Livio L, Francescato G, Braga M, Radaelli G, Riva E: Double-blind, placebo-controlled trial comparing effects of supplementation with two different combinations of micronutrients delivered as Sprinkles on growthm anemia, and iron deficiency in Cambodian infants. J Pediatr Gastroenterol Nutr 2006, 42: 306–312.CrossRefPubMed Giovannini M, Sala D, Usuelli M, Livio L, Francescato G, Braga M, Radaelli G, Riva E: Double-blind, placebo-controlled trial comparing effects of supplementation with two different combinations of micronutrients delivered as Sprinkles on growthm anemia, and iron deficiency in Cambodian infants. J Pediatr Gastroenterol Nutr 2006, 42: 306–312.CrossRefPubMed
58.
go back to reference Smuts CM, Dhansay MA, Faber M, Van Stuijvenberg ME, Swanevelder S, Gross R, Benadé AJS: Efficacy of multiple micronutrient supplementation for improving anemia, micronutrient status, and growth in South African infants. J Nutr 2005, 135: 653S-659S.PubMed Smuts CM, Dhansay MA, Faber M, Van Stuijvenberg ME, Swanevelder S, Gross R, Benadé AJS: Efficacy of multiple micronutrient supplementation for improving anemia, micronutrient status, and growth in South African infants. J Nutr 2005, 135: 653S-659S.PubMed
59.
go back to reference Untoro J, Karyadi E, Wibowo L, Erhardt MW, Gross R: Multiple micronutrient supplements improve micronutrient status and anemia but not growth and morbidity of Indonesian infants: a randomized, double-blind, placebo-controlled trial. J Nutr 2005, 135: 639S-645S.PubMed Untoro J, Karyadi E, Wibowo L, Erhardt MW, Gross R: Multiple micronutrient supplements improve micronutrient status and anemia but not growth and morbidity of Indonesian infants: a randomized, double-blind, placebo-controlled trial. J Nutr 2005, 135: 639S-645S.PubMed
60.
go back to reference Zlotkin S, Arthur P, Antwi KY, Yeung G: Treatment of anemia with microencapsulated ferrous fumarate plus ascorbic acid supplied as sprinkles to complementary (weaning) foods. Am J Clin Nutr 2001, 74: 791–795.PubMed Zlotkin S, Arthur P, Antwi KY, Yeung G: Treatment of anemia with microencapsulated ferrous fumarate plus ascorbic acid supplied as sprinkles to complementary (weaning) foods. Am J Clin Nutr 2001, 74: 791–795.PubMed
61.
go back to reference Brooker S, Kabatereine NB, Fleming F, Devlin N: Cost and cost-effectiveness of nationwide school-based helminth control in Uganda: intra-country variation and effects of scaling-up. Health Policy Plan 2008, 23: 24–35.PubMedCentralCrossRefPubMed Brooker S, Kabatereine NB, Fleming F, Devlin N: Cost and cost-effectiveness of nationwide school-based helminth control in Uganda: intra-country variation and effects of scaling-up. Health Policy Plan 2008, 23: 24–35.PubMedCentralCrossRefPubMed
62.
go back to reference Guyatt HL, Brooker S, Kihamia CM, Hall A, Bundy DAP: Evaluation of efficacy of school-based anthelmintic treatments against anaemia in children in the United Republic of Tanzania. Bull World Health Organ 2001, 79: 695–703.PubMedCentralPubMed Guyatt HL, Brooker S, Kihamia CM, Hall A, Bundy DAP: Evaluation of efficacy of school-based anthelmintic treatments against anaemia in children in the United Republic of Tanzania. Bull World Health Organ 2001, 79: 695–703.PubMedCentralPubMed
63.
go back to reference Stoltzfus RJ, Albonico M, Chwaya HM, Tielsch JM, Schulze KJ, Savioli L: Effects of the Zanzibar school-based deworming program on iron status of children. Am J Clin Nutr 1998, 68: 179–186.PubMed Stoltzfus RJ, Albonico M, Chwaya HM, Tielsch JM, Schulze KJ, Savioli L: Effects of the Zanzibar school-based deworming program on iron status of children. Am J Clin Nutr 1998, 68: 179–186.PubMed
64.
go back to reference Kosek M, Bern C, Guerrant RL: The global burden of diarrhoeal disease, as estimated from studies published between 1992 and 2000. Bull World Health Organ 2003, 81: 197–204.PubMedCentralPubMed Kosek M, Bern C, Guerrant RL: The global burden of diarrhoeal disease, as estimated from studies published between 1992 and 2000. Bull World Health Organ 2003, 81: 197–204.PubMedCentralPubMed
65.
go back to reference Taylor CE, Greenough WBI: Control of diarrheal diseases. Annu Rev Public Health 1989, 10: 221–244.CrossRefPubMed Taylor CE, Greenough WBI: Control of diarrheal diseases. Annu Rev Public Health 1989, 10: 221–244.CrossRefPubMed
66.
go back to reference Feachem RG: Interventions for the control of diarrhoeal diseases among young children: supplementary feeding programs. Bull World Health Organ 1983, 61: 967–979.PubMedCentralPubMed Feachem RG: Interventions for the control of diarrhoeal diseases among young children: supplementary feeding programs. Bull World Health Organ 1983, 61: 967–979.PubMedCentralPubMed
67.
go back to reference Sazawal S, Black RE, Bhan MK, Jalla S, Sinha A, Bhandari N: Efficacy of zinc supplementation in reducing the incidence and prevalence of acute diarrhea-a community-based, double-blind, controlled trial. Am J Clin Nutr 1997, 66: 413–418.PubMed Sazawal S, Black RE, Bhan MK, Jalla S, Sinha A, Bhandari N: Efficacy of zinc supplementation in reducing the incidence and prevalence of acute diarrhea-a community-based, double-blind, controlled trial. Am J Clin Nutr 1997, 66: 413–418.PubMed
68.
go back to reference WHO, UNICEF: WHO-UNICEF Joint statement on the clinical management of acute diarrhea. Geneva: World Health Assembly; 2004. WHO, UNICEF: WHO-UNICEF Joint statement on the clinical management of acute diarrhea. Geneva: World Health Assembly; 2004.
69.
go back to reference Horton S, Sanghvi T, Phillips M, Fiedler JL, Perez-Escamilla R, Lutter C, Rivera A, Segall-Correa AM: Breastfeeding promotion and priority setting in health. Health Policy Plan 1996, 11: 156–168.CrossRefPubMed Horton S, Sanghvi T, Phillips M, Fiedler JL, Perez-Escamilla R, Lutter C, Rivera A, Segall-Correa AM: Breastfeeding promotion and priority setting in health. Health Policy Plan 1996, 11: 156–168.CrossRefPubMed
70.
go back to reference Thompson B: Combating iron deficiency: food-based approaches. In Combating micronutrient deficiencies: food-based approaches. Edited by: Thompson B, Amoroso L. Rome: Food and Agriculture Organization; 2011. Thompson B: Combating iron deficiency: food-based approaches. In Combating micronutrient deficiencies: food-based approaches. Edited by: Thompson B, Amoroso L. Rome: Food and Agriculture Organization; 2011.
71.
go back to reference Ruel MT: Can food-based strategies help reduce vitamin A and iron deficiencies? A review of recent evidence. Washington, DC: International Food Policy Research Institute; 2001. Ruel MT: Can food-based strategies help reduce vitamin A and iron deficiencies? A review of recent evidence. Washington, DC: International Food Policy Research Institute; 2001.
72.
go back to reference Varley R, Tarvid J, Chao D: A reassessment of the cost-effectiveness of water and sanitation interventions in programmes for controlling childhood diarrhoea. Bull World Health Organ 1998, 76: 617–631.PubMedCentralPubMed Varley R, Tarvid J, Chao D: A reassessment of the cost-effectiveness of water and sanitation interventions in programmes for controlling childhood diarrhoea. Bull World Health Organ 1998, 76: 617–631.PubMedCentralPubMed
73.
go back to reference Shrestha RK, Marseille E, Kahn JG, Lule JR, Pitter C, Blandford JM, Bunnell R, Coutinho A, Kizito F, Quick R, Mermin J: Cost-effectiveness of home-based chlorination and safe water storage in reducing diarrhea among HIV-affected households in rural Uganda. Am J Trop Med Hyg 2006, 74: 884–890.PubMed Shrestha RK, Marseille E, Kahn JG, Lule JR, Pitter C, Blandford JM, Bunnell R, Coutinho A, Kizito F, Quick R, Mermin J: Cost-effectiveness of home-based chlorination and safe water storage in reducing diarrhea among HIV-affected households in rural Uganda. Am J Trop Med Hyg 2006, 74: 884–890.PubMed
74.
go back to reference Borghi J, Guinness L, Ouedraogo J, Curtis V: Is hygiene promotion cost-effective? A case study in Burkina Faso. Trop Med Int Health 2002, 7: 960–969.CrossRefPubMed Borghi J, Guinness L, Ouedraogo J, Curtis V: Is hygiene promotion cost-effective? A case study in Burkina Faso. Trop Med Int Health 2002, 7: 960–969.CrossRefPubMed
76.
go back to reference Ruel MT, Menon P, Habicht J-P, Loechl C, Bergeron G, Pelto G, Arimond M, Maluccio J, Michaud L, Hankebo B: Age-based preventive targeting of food assistance and behaviour change and communication for reduction of childhood undernutrition in Haiti: a cluster randomised trial. Lancet 2008, 371: 588–595.CrossRefPubMed Ruel MT, Menon P, Habicht J-P, Loechl C, Bergeron G, Pelto G, Arimond M, Maluccio J, Michaud L, Hankebo B: Age-based preventive targeting of food assistance and behaviour change and communication for reduction of childhood undernutrition in Haiti: a cluster randomised trial. Lancet 2008, 371: 588–595.CrossRefPubMed
77.
go back to reference Lazzerini M, Rubert L, Pani P: Specially formulated foods for treating children with moderate acute malnutrition in low- and middle-income countries. Cochrane Databse of Systematic Reviews 2013. doi:CD009584 Lazzerini M, Rubert L, Pani P: Specially formulated foods for treating children with moderate acute malnutrition in low- and middle-income countries. Cochrane Databse of Systematic Reviews 2013. doi:CD009584
78.
go back to reference WHO WFP: UNICEF: Preventing and controlling micronutrient deficiencies in populations affected by an emergency. Geneva: World Health Organization; 2007. WHO WFP: UNICEF: Preventing and controlling micronutrient deficiencies in populations affected by an emergency. Geneva: World Health Organization; 2007.
79.
go back to reference De Pee S, Moench-Pfanner R, Martini E, Zlotkin S, Darnton-Hill I, Bloem MW: Home fortification in emergency response and transition programming: Experiences in Aceh and Nias, Indonesia. Food and Nutrition Bulletin 2007, 28: 189–197.PubMed De Pee S, Moench-Pfanner R, Martini E, Zlotkin S, Darnton-Hill I, Bloem MW: Home fortification in emergency response and transition programming: Experiences in Aceh and Nias, Indonesia. Food and Nutrition Bulletin 2007, 28: 189–197.PubMed
Metadata
Title
Protecting child health and nutrition status with ready-to-use food in addition to food assistance in urban Chad: a cost-effectiveness analysis
Authors
Chloe Puett
Cécile Salpéteur
Elisabeth Lacroix
Freddy Houngbé
Myriam Aït-Aïssa
Anne-Dominique Israël
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Cost Effectiveness and Resource Allocation / Issue 1/2013
Electronic ISSN: 1478-7547
DOI
https://doi.org/10.1186/1478-7547-11-27

Other articles of this Issue 1/2013

Cost Effectiveness and Resource Allocation 1/2013 Go to the issue