Skip to main content
Top
Published in: World Journal of Surgical Oncology 1/2011

Open Access 01-12-2011 | Research

Usefulness of ultrasonography for the evaluation of cervical lymphadenopathy

Authors: Rahul Khanna, Avinash Dutt Sharma, Seema Khanna, Mohan Kumar, Ram C Shukla

Published in: World Journal of Surgical Oncology | Issue 1/2011

Login to get access

Abstract

Aim

To evaluate the role of ultrasonography for differentiating cervical lymphadenopathy due to tuberculosis, metastasis and lymphoma.

Methods

Ultrasonography of the neck nodes was carried out prior to FNAC in 192 patients using a 10 mHz linear transducer. The sonographic findings were then correlated with the definitive tissue diagnosis obtained by FNAC or lymph node biopsy.

Results

The most significant distinguishing feature was strong internal echoes seen in 84% of tubercular lymph nodes. This finding was found in only 11% of metastatic nodes and absent in lymphomatous nodes. The other findings such as L/S ratio, irregular margins, hypoechoic center, fusion tendency, peripheral halo and absent hilus were helpful in differentiating reactive from diseased nodes but showed considerable overlap in the 3 groups of tubercular, metastatic and lymphoma lymph nodes.

Conclusion

Ultrasonography is noninvasive and can give useful clues in the diagnosis of cervical lymphadenopathy. It should be interpreted in conjunction with FNAC result. Ideally ultra-sonographic guided FNAC should be obtained from the sonographically most representative node. In FNAC indeterminate cases, sonographic features may obviate the need for an invasive lymph node biopsy.
Literature
1.
go back to reference Haque MA, Talukder SI: Evaluation of fine needle aspiration cytology (FNAC) of lymphnodes in Mymensingh. Mymensingh Med J. 2003, 12 (11): 33-5.PubMed Haque MA, Talukder SI: Evaluation of fine needle aspiration cytology (FNAC) of lymphnodes in Mymensingh. Mymensingh Med J. 2003, 12 (11): 33-5.PubMed
2.
go back to reference Ying M, Ahuja A, Evans R: Cervical lymphadenopathy: sonographic differentiation between tuberculous nodes and nodal metastases from non-head and neck carcinomas. J Clin Ultrasound. 1998, 26: 383-389. 10.1002/(SICI)1097-0096(199810)26:8<383::AID-JCU2>3.0.CO;2-E.CrossRefPubMed Ying M, Ahuja A, Evans R: Cervical lymphadenopathy: sonographic differentiation between tuberculous nodes and nodal metastases from non-head and neck carcinomas. J Clin Ultrasound. 1998, 26: 383-389. 10.1002/(SICI)1097-0096(199810)26:8<383::AID-JCU2>3.0.CO;2-E.CrossRefPubMed
3.
go back to reference Asai S, Miyachi H, Suzuki K, Shimamura K, Ando Y: Ultrasonographic differentiation between tuberculous lymphadenitis and malignant lymph nodes. J Ultrasound Med. 2001, 20: 533-538.PubMed Asai S, Miyachi H, Suzuki K, Shimamura K, Ando Y: Ultrasonographic differentiation between tuberculous lymphadenitis and malignant lymph nodes. J Ultrasound Med. 2001, 20: 533-538.PubMed
4.
go back to reference Steinkamp HJ, Cornehl M, Hosten N, Pegios W, Vogl T, Felic R: Cervical lymphadenopathy: ratio of long to short axis diameter as a predictor of malignancy. Br J Radiol. 1995, 68 (807): 266-70. 10.1259/0007-1285-68-807-266.CrossRefPubMed Steinkamp HJ, Cornehl M, Hosten N, Pegios W, Vogl T, Felic R: Cervical lymphadenopathy: ratio of long to short axis diameter as a predictor of malignancy. Br J Radiol. 1995, 68 (807): 266-70. 10.1259/0007-1285-68-807-266.CrossRefPubMed
5.
go back to reference Kim HC, Han MH, Do KH, Kim KH, Choi HJ, Kim AY, Sung MW, Chang KH: Volume of cervical lymph nodes using 3 D ultrasonography. Differentiation of metastatic from reactive lymphadenopathy in primary head and neck malignancy. Acta Radiol. 2002, 43 (6): 571-4. 10.1034/j.1600-0455.2002.430606.x.CrossRefPubMed Kim HC, Han MH, Do KH, Kim KH, Choi HJ, Kim AY, Sung MW, Chang KH: Volume of cervical lymph nodes using 3 D ultrasonography. Differentiation of metastatic from reactive lymphadenopathy in primary head and neck malignancy. Acta Radiol. 2002, 43 (6): 571-4. 10.1034/j.1600-0455.2002.430606.x.CrossRefPubMed
6.
go back to reference Ying M, Ahuja A, Brook F: Accuracy of sonographic vascular features in differentiating different causes of cervical lymphadenopathy. Ultrasound Med Biol. 2004, 30 (4): 441-7. 10.1016/j.ultrasmedbio.2003.12.009.CrossRefPubMed Ying M, Ahuja A, Brook F: Accuracy of sonographic vascular features in differentiating different causes of cervical lymphadenopathy. Ultrasound Med Biol. 2004, 30 (4): 441-7. 10.1016/j.ultrasmedbio.2003.12.009.CrossRefPubMed
7.
go back to reference Ho SS, Metreweli C, Ahuja AT: Does anybody know how we should measure Doppler parameters in lymph nodes?. Clinical Radiology. 2001, 56: 124-126. 10.1053/crad.2000.0588.CrossRefPubMed Ho SS, Metreweli C, Ahuja AT: Does anybody know how we should measure Doppler parameters in lymph nodes?. Clinical Radiology. 2001, 56: 124-126. 10.1053/crad.2000.0588.CrossRefPubMed
8.
go back to reference Mikami Y, Kamato S, Kawobata K, Nigaari T, Hoki K, Mitani H, Beppu T: Ultrasonographic evaluation of metastatic cervical lymph nodes in head and neck cancers. Nippon Jibiinkoka Gakkai Kaiho. 2000, 103 (7): 812-20.CrossRefPubMed Mikami Y, Kamato S, Kawobata K, Nigaari T, Hoki K, Mitani H, Beppu T: Ultrasonographic evaluation of metastatic cervical lymph nodes in head and neck cancers. Nippon Jibiinkoka Gakkai Kaiho. 2000, 103 (7): 812-20.CrossRefPubMed
Metadata
Title
Usefulness of ultrasonography for the evaluation of cervical lymphadenopathy
Authors
Rahul Khanna
Avinash Dutt Sharma
Seema Khanna
Mohan Kumar
Ram C Shukla
Publication date
01-12-2011
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2011
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/1477-7819-9-29

Other articles of this Issue 1/2011

World Journal of Surgical Oncology 1/2011 Go to the issue