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Published in: World Journal of Surgical Oncology 1/2010

Open Access 01-12-2010 | Case report

Carcinoma ex pleomorphic adenoma of soft palate with cavernous sinus invasion

Authors: Hsuan-Ho Chen, Li-Yu Lee, Shy-Chyi Chin, I-How Chen, Chun-Ta Liao, Shiang-Fu Huang

Published in: World Journal of Surgical Oncology | Issue 1/2010

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Abstract

Background

Carcinoma ex pleomorphic adenoma (CXPA) is an aggressive salivary gland malignancy and rare in minor salivary gland. A soft palate CXPA initially presenting as direct cavernous sinus (CS) invasion is very rare.

Case Presentation

A 60-year-old male had a 3-month history of a small soft palatal mass with progressing left cheek numbness, proptosis, and disturbed vision. Biopsy of soft palatal tumor showed pleomorphic adenoma. Magnetic resonance imaging showed a tumor involving left maxilla, and extended from pterygopalatine fossa, inferior orbital fissure to CS. Excision of tumor revealed CXPA. Adjuvant concomitant chemo-radiation therapy (CCRT) was given. The tumor recurred 5 months later in left CS which was re-treated with CCRT. The disease status was stable at 2 years after the diagnosis of CXPA.

Conclusion

We present this case to emphasize that patients with symptoms such as facial numbness, proptosis and disturbed vision should be carefully investigated for lesions invading CS by perineural spread.
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Metadata
Title
Carcinoma ex pleomorphic adenoma of soft palate with cavernous sinus invasion
Authors
Hsuan-Ho Chen
Li-Yu Lee
Shy-Chyi Chin
I-How Chen
Chun-Ta Liao
Shiang-Fu Huang
Publication date
01-12-2010
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2010
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/1477-7819-8-24

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