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Open Access 01-12-2014 | Review

Idiopathic desmoid-type fibromatosis of the pancreatic head: case report and literature review

Authors: Changjun Jia, Baoling Tian, Chaoliu Dai, Xinlu Wang, Xianmin Bu, Feng Xu

Published in: World Journal of Surgical Oncology | Issue 1/2014

Abstract

Desmoid-type fibromatosis (DTF) is an uncommon nonmetastatic fibrous neoplasm. Sporadic intraperitoneal DTF is rarely described in current literature. We herein report a case of DTF of unknown cause involving the pancreatic head. A 41-year-old man presented with recurrent epigastric pain and weight loss. An abdominal computed tomography scan showed a well-delineated solid cystic mass inside the pancreatic head. Pylorus-preserving pancreaticoduodenectomy was performed due to the patient’s debilitating symptoms and suspected malignancy. The pathological examination revealed massive fibroblastic proliferation arising from the musculoaponeurotic tissues, consistent with a diagnosis of DTF. Immunohistochemical phenotyping determined positive immunoreactivity to vimentin and β-catenin, but negative immunoreactivity to smooth muscle actin, CD117, CD34, or S-100, confirming the diagnosis of DTF. No local recurrence or distant metastasis was found during a 24-month follow-up. Radical resection is recommended as first-line treatment for pancreatic DTF. Long-term follow-up studies are required to establish the prognosis of pancreatic DTF.

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Title: Idiopathic desmoid-type fibromatosis of the pancreatic head: case report and literature review
Authors: Changjun Jia
Baoling Tian
Chaoliu Dai
Xinlu Wang
Xianmin Bu
Feng Xu
Publication date: 01-12-2014
Publisher: BioMed Central
Published in: World Journal of Surgical Oncology / Issue 1/2014
Electronic ISSN: 1477-7819
DOI: https://doi.org/10.1186/1477-7819-12-103

At a glance: The ONWARDS insulin icodec trials

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Idiopathic desmoid-type fibromatosis of the pancreatic head: case report and literature review

Abstract

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

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