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Published in: Health and Quality of Life Outcomes 1/2009

Open Access 01-12-2009 | Research

Factors influencing quality of life in Moroccan postmenopausal women with osteoporotic vertebral fracture assessed by ECOS 16 questionnaire

Authors: Fatima E Abourazzak, Fadoua Allali, Samira Rostom, Ihsane Hmamouchi, Linda Ichchou, Laila El Mansouri, Loubna Bennani, Hamza Khazzani, Redouane Abouqal, Najia Hajjaj-Hassouni

Published in: Health and Quality of Life Outcomes | Issue 1/2009

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Abstract

Objective

The aim of the study was to evaluate factors influencing quality of life (QOL) in Moroccan postmenopausal women with osteoporotic vertebral fracture assessed by the Arabic version of ECOS 16 questionnaire.

Methods

357 postmenopausal women were included in this study. The participants underwent bone mineral density (BMD) measurements by DXA of the lumbar spine and the total hip as well as X-ray examination of the thoraco-lumbar spine to identify subclinical vertebral fractures. Patients were asked to complete a questionnaire on clinical and sociodemographic parameters, and osteoporosis risk factors. The Arabic version of the ECOS16 (Assessment of health related quality of life in osteoporosis questionnaire) was used to assess quality of life.

Results

The mean age was 58 ± 7.8 years, and the mean BMI was 28.3 ± 4.8 kg/m2. One hundred and eight women (30.1%) were osteoporotic and 46.7% had vertebral fractures. Most were categorized as Grade1 (75%). Three independent factors were associated with a poor quality of life: low educational level (p = 0,01), vertebral fracture (p = 0,03), and history of peripheral fracture (p = 0,006). Worse QOL was observed in the group with vertebral fracture in all domains except "pain": Physical functioning (p = 0,002); Fear of illness (p = 0,001); and Psychosocial functioning (p = 0,007). The number of fractures was a determinant of a low QOL, as indicated by an increased score in physical functioning (p = 0,01), fear of illness (p = 0,007), and total score (p = 0,01) after adjusting on age and educational level. Patients with higher Genant score had low QOL in these two domains too (p = 0,002; p = 0,001 respectively), and in the total score (p = 0,01) after adjusting on age and educational level.

Conclusion

Our current data showed that the quality of life assessed by the Arabic version of the ECOS 16 questionnaire is decreased in post menopausal women with prevalent vertebral fractures, with the increasing number and the severity of vertebral fractures.
Literature
1.
go back to reference Haczynski J, Jakimiuk A: Vertebral fractures: a hidden problem of osteoporosis. Med Sci Monit 2001,7(5):1108–1117.PubMed Haczynski J, Jakimiuk A: Vertebral fractures: a hidden problem of osteoporosis. Med Sci Monit 2001,7(5):1108–1117.PubMed
2.
go back to reference Cook DJ, Guyatt GH, Adachi JD: Quality of life issues in women with vertebral fractures due to osteoporosis. Arthritis Rheum 1993,36(6):2469–2475. 10.1002/art.1780360603CrossRef Cook DJ, Guyatt GH, Adachi JD: Quality of life issues in women with vertebral fractures due to osteoporosis. Arthritis Rheum 1993,36(6):2469–2475. 10.1002/art.1780360603CrossRef
3.
go back to reference Oleksik A, Lips P, Dawson A, Minshall ME, Shen W, Cooper C, Kanis J: Healthrelated quality of life in postmenopausal women with low BMD with or without prevalent vertebral fractures. J Bone Miner Res 2000,15(7):1384–1392. 10.1359/jbmr.2000.15.7.1384CrossRefPubMed Oleksik A, Lips P, Dawson A, Minshall ME, Shen W, Cooper C, Kanis J: Healthrelated quality of life in postmenopausal women with low BMD with or without prevalent vertebral fractures. J Bone Miner Res 2000,15(7):1384–1392. 10.1359/jbmr.2000.15.7.1384CrossRefPubMed
4.
go back to reference Hall SE, Criddle RA, Comito TL, Prince RL: A case control study of quality of life and functional impairment in women with long standing vertebral osteoporotic fracture. Osteoporos Int 1999, 9: 508–515. 10.1007/s001980050178CrossRefPubMed Hall SE, Criddle RA, Comito TL, Prince RL: A case control study of quality of life and functional impairment in women with long standing vertebral osteoporotic fracture. Osteoporos Int 1999, 9: 508–515. 10.1007/s001980050178CrossRefPubMed
5.
go back to reference Gold DT: The clinical impact of vertebral fractures: quality of life in women with osteoporosis. Bone 1996, 18: 185S-189S. 10.1016/8756-3282(95)00500-5CrossRefPubMed Gold DT: The clinical impact of vertebral fractures: quality of life in women with osteoporosis. Bone 1996, 18: 185S-189S. 10.1016/8756-3282(95)00500-5CrossRefPubMed
6.
go back to reference Badia X, Diez-Perez A, Alvarez-Sanz C, for the Spanish Greco study group: Measuring quality of life in women with vertebral fractures due to osteoporosis: A comparison of the OQLQ and QUALEFFO. Qual Life Res 2001, 10: 307–17. 10.1023/A:1012200508847CrossRefPubMed Badia X, Diez-Perez A, Alvarez-Sanz C, for the Spanish Greco study group: Measuring quality of life in women with vertebral fractures due to osteoporosis: A comparison of the OQLQ and QUALEFFO. Qual Life Res 2001, 10: 307–17. 10.1023/A:1012200508847CrossRefPubMed
7.
go back to reference Osteoporosis Quality of Life Study Group: Measuring quality of life in women with osteoporosis. Osteoporos Int 1997, 7: 478–87. 10.1007/PL00004151CrossRef Osteoporosis Quality of Life Study Group: Measuring quality of life in women with osteoporosis. Osteoporos Int 1997, 7: 478–87. 10.1007/PL00004151CrossRef
8.
go back to reference Cantarelli FB, Szejnfeld VL, Oliveira LM, Ciconelli RM, Ferraz MB: Quality of life in patients with osteoporosis fractures: cultural adaptation, reliability and validity of the Osteoporosis Assessment Questionnaire. Clin Exp Rheumatol 1999, 17: 547–51.PubMed Cantarelli FB, Szejnfeld VL, Oliveira LM, Ciconelli RM, Ferraz MB: Quality of life in patients with osteoporosis fractures: cultural adaptation, reliability and validity of the Osteoporosis Assessment Questionnaire. Clin Exp Rheumatol 1999, 17: 547–51.PubMed
9.
go back to reference Oglesby AK, Minshall ME, Shen W, Xie S, Silverman SL: The impact of incident vertebral and non-vertebral fragility fractures on health-related quality of life in established postmenopausal osteoporosis: results from the teriparatide randomized, placebo-controlled trial in postmenopausal women. J Rheumatol 2003, 30: 1579–83.PubMed Oglesby AK, Minshall ME, Shen W, Xie S, Silverman SL: The impact of incident vertebral and non-vertebral fragility fractures on health-related quality of life in established postmenopausal osteoporosis: results from the teriparatide randomized, placebo-controlled trial in postmenopausal women. J Rheumatol 2003, 30: 1579–83.PubMed
10.
go back to reference Crans GG, Silverman SL, Genant HK, Glass EV, Krege JH: Association of severe vertebral fractures with reduced quality of life. Reduction in the incidence of severe vertebral fractures by teriparatide. Arthritis Rheum 2004, 50: 4028–34. 10.1002/art.20671CrossRefPubMed Crans GG, Silverman SL, Genant HK, Glass EV, Krege JH: Association of severe vertebral fractures with reduced quality of life. Reduction in the incidence of severe vertebral fractures by teriparatide. Arthritis Rheum 2004, 50: 4028–34. 10.1002/art.20671CrossRefPubMed
11.
go back to reference Silverman SL, Minshall ME, Shen W, Harper KD, Xie S, on behalf of the Health-Related Quality of Life Subgroup of the Multiple Outcomes of Raloxifene Evaluation Study: The relationship of health-related quality of life to prevalent and incident vertebral fractures in postmenopausal women with osteoporosis: results from the Multiple Outcomes of Raloxifene Evaluation Study. Arthritis Rheum 2001, 44: 2611–9. 10.1002/1529-0131(200111)44:11<2611::AID-ART441>3.0.CO;2-NCrossRefPubMed Silverman SL, Minshall ME, Shen W, Harper KD, Xie S, on behalf of the Health-Related Quality of Life Subgroup of the Multiple Outcomes of Raloxifene Evaluation Study: The relationship of health-related quality of life to prevalent and incident vertebral fractures in postmenopausal women with osteoporosis: results from the Multiple Outcomes of Raloxifene Evaluation Study. Arthritis Rheum 2001, 44: 2611–9. 10.1002/1529-0131(200111)44:11<2611::AID-ART441>3.0.CO;2-NCrossRefPubMed
12.
go back to reference Lydick E, Itkin S, Zimmerman I, Yawn B, Love B, Kleerekoper M, Ross P, Martin A, Holmes R: Development and validation of a discriminative quality of life questionnaire for osteoporosis (the OPTQoL). J Bone Min Res 1997, 12: 456–73. 10.1359/jbmr.1997.12.3.456CrossRef Lydick E, Itkin S, Zimmerman I, Yawn B, Love B, Kleerekoper M, Ross P, Martin A, Holmes R: Development and validation of a discriminative quality of life questionnaire for osteoporosis (the OPTQoL). J Bone Min Res 1997, 12: 456–73. 10.1359/jbmr.1997.12.3.456CrossRef
13.
go back to reference Martin AR, Sornay-Rendu E, Chandler JM, Duboeuf F, Girman CJ, Delmas PD: The impact of osteoporosis on quality-oflife: the OFELY cohort. Bone 2002, 31: 32–6. 10.1016/S8756-3282(02)00787-1CrossRefPubMed Martin AR, Sornay-Rendu E, Chandler JM, Duboeuf F, Girman CJ, Delmas PD: The impact of osteoporosis on quality-oflife: the OFELY cohort. Bone 2002, 31: 32–6. 10.1016/S8756-3282(02)00787-1CrossRefPubMed
14.
go back to reference Chandler JM, Martin AR, Girman C, Ross PD, Love-McClung B, Lydick E, Yawn BP: Reliability of an osteoporosis-targeted quality of life survey instrument for use in the community: OPTQoL. Osteoporos Int 1998, 8: 127–35. 10.1007/BF02672508CrossRefPubMed Chandler JM, Martin AR, Girman C, Ross PD, Love-McClung B, Lydick E, Yawn BP: Reliability of an osteoporosis-targeted quality of life survey instrument for use in the community: OPTQoL. Osteoporos Int 1998, 8: 127–35. 10.1007/BF02672508CrossRefPubMed
15.
go back to reference Oleksik A, Lips P, Dawson A, Minshall ME, Shen W, Cooper C, Kanis J: Healthrelated quality of life in postmenopausal women with low BMD with or without prevalent vertebral fractures. J Bone Miner Res 2000, 15: 1384–92. 10.1359/jbmr.2000.15.7.1384CrossRefPubMed Oleksik A, Lips P, Dawson A, Minshall ME, Shen W, Cooper C, Kanis J: Healthrelated quality of life in postmenopausal women with low BMD with or without prevalent vertebral fractures. J Bone Miner Res 2000, 15: 1384–92. 10.1359/jbmr.2000.15.7.1384CrossRefPubMed
16.
go back to reference Koçyigit H, Gulseren S, Erol A, Hizli N: The reliability and validity of the Turkish version of quality of life questionnaire of the European Foundation for Osteoporosis (QUALEFFO). Clin Rheumatol 2003, 22: 18–23. 10.1007/s10067-002-0653-6CrossRefPubMed Koçyigit H, Gulseren S, Erol A, Hizli N: The reliability and validity of the Turkish version of quality of life questionnaire of the European Foundation for Osteoporosis (QUALEFFO). Clin Rheumatol 2003, 22: 18–23. 10.1007/s10067-002-0653-6CrossRefPubMed
17.
go back to reference Oleksik AM, Ewing S, Shen W, Van Schoor NM, Lips P: Impact of incident vertebral fractures on health related quality of life (HRQOL) in postmenopausal women with prevalent vertebral fractures. Osteoporos Int 2005, 16: 861–70. 10.1007/s00198-004-1774-3CrossRefPubMed Oleksik AM, Ewing S, Shen W, Van Schoor NM, Lips P: Impact of incident vertebral fractures on health related quality of life (HRQOL) in postmenopausal women with prevalent vertebral fractures. Osteoporos Int 2005, 16: 861–70. 10.1007/s00198-004-1774-3CrossRefPubMed
18.
go back to reference Romagnoli E, Carnevale V, Nofroni I, D'Erasmo E, Paglia F, De Geronimo S, Pepe J, Raejntroph N, Maranghi M, Minisola S: Quality of life in ambulatory postmenopausal women: the impact of reduced bone mineral density and subclinical vertebral fractures. Osteoporos Int 2004, 15: 975–80. 10.1007/s00198-004-1633-2CrossRefPubMed Romagnoli E, Carnevale V, Nofroni I, D'Erasmo E, Paglia F, De Geronimo S, Pepe J, Raejntroph N, Maranghi M, Minisola S: Quality of life in ambulatory postmenopausal women: the impact of reduced bone mineral density and subclinical vertebral fractures. Osteoporos Int 2004, 15: 975–80. 10.1007/s00198-004-1633-2CrossRefPubMed
19.
go back to reference Lips P, Cooper C, Agnusdei D, Caulin F, Egger P, Johnell O, Kanis JA, Kellingray S, Leplege A, Liberman UA, McCloskey E, Minne H, Reeve J, Reginster JY, Scholz M, Todd C, de Vernejoul MC, Wiklund I: Quality of life in patients with vertebral fractures: validation of the Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO). Working Party for Quality of Life of the European Foundation for Osteoporosis. Osteoporos Int 1999, 10: 150–60. 10.1007/s001980050210CrossRefPubMed Lips P, Cooper C, Agnusdei D, Caulin F, Egger P, Johnell O, Kanis JA, Kellingray S, Leplege A, Liberman UA, McCloskey E, Minne H, Reeve J, Reginster JY, Scholz M, Todd C, de Vernejoul MC, Wiklund I: Quality of life in patients with vertebral fractures: validation of the Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO). Working Party for Quality of Life of the European Foundation for Osteoporosis. Osteoporos Int 1999, 10: 150–60. 10.1007/s001980050210CrossRefPubMed
20.
go back to reference Murrell P, Todd CJ, Martin A, Walton J, Lips P, Reeve J, on behalf of the Working Party for Quality of Life of the International Osteoporosis Foundation: Postal administration compared with nurse-supported administration of the QUALEFFO-41 in a population sample: comparison of results and assessment of psychometric properties. Osteoporos Int 2001, 12: 672–9. 10.1007/s001980170067CrossRefPubMed Murrell P, Todd CJ, Martin A, Walton J, Lips P, Reeve J, on behalf of the Working Party for Quality of Life of the International Osteoporosis Foundation: Postal administration compared with nurse-supported administration of the QUALEFFO-41 in a population sample: comparison of results and assessment of psychometric properties. Osteoporos Int 2001, 12: 672–9. 10.1007/s001980170067CrossRefPubMed
21.
go back to reference Cook DJ, Guyatt GH, Adachi JD, Clifton J, Griffith LE, Epstein RS, Juniper EF: Quality of life issues in women with vertebral fractures due to osteoporosis. Arthritis Rheum 1993, 36: 750–6. 10.1002/art.1780360603CrossRefPubMed Cook DJ, Guyatt GH, Adachi JD, Clifton J, Griffith LE, Epstein RS, Juniper EF: Quality of life issues in women with vertebral fractures due to osteoporosis. Arthritis Rheum 1993, 36: 750–6. 10.1002/art.1780360603CrossRefPubMed
22.
go back to reference Cook DJ, Guyatt GH, Adachi JD, Epstein RS, Juniper EF: Development and validation of the mini-Osteoporosis Quality of Life Questionnaire (OQLQ) in osteoporosis women with back pain due to vertebral fractures. Osteoporosis quality of life study group. Osteoporos Int 1999, 10: 207–13. 10.1007/s001980050217CrossRefPubMed Cook DJ, Guyatt GH, Adachi JD, Epstein RS, Juniper EF: Development and validation of the mini-Osteoporosis Quality of Life Questionnaire (OQLQ) in osteoporosis women with back pain due to vertebral fractures. Osteoporosis quality of life study group. Osteoporos Int 1999, 10: 207–13. 10.1007/s001980050217CrossRefPubMed
23.
go back to reference Badia X, Diez-Perez A, Lahoz R, Lizan L, Nogues X, Iborra J: The ECOS-16 questionnaire for the evaluation of health related quality of life in postmenopausal women with osteoporosis. Health Qual Life Outcomes 2004, 2: 41. 10.1186/1477-7525-2-41PubMedCentralCrossRefPubMed Badia X, Diez-Perez A, Lahoz R, Lizan L, Nogues X, Iborra J: The ECOS-16 questionnaire for the evaluation of health related quality of life in postmenopausal women with osteoporosis. Health Qual Life Outcomes 2004, 2: 41. 10.1186/1477-7525-2-41PubMedCentralCrossRefPubMed
24.
go back to reference Genant HK, Wu CY, Van Kuijk C, Nevitt MC: Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res 1993,8(9):1137–1148.CrossRefPubMed Genant HK, Wu CY, Van Kuijk C, Nevitt MC: Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res 1993,8(9):1137–1148.CrossRefPubMed
25.
go back to reference Worls Health Organisation Study Group: Assessment of fracture risk and its application to screening for post-menopausal osteoporosis. In WHO Technical Report Series, No.843. WHO, Geneva; 1994. Worls Health Organisation Study Group: Assessment of fracture risk and its application to screening for post-menopausal osteoporosis. In WHO Technical Report Series, No.843. WHO, Geneva; 1994.
26.
go back to reference Guillemin F, Bombardier C, Beaton D: Cross-cultural adaptation of health-related quality of life measures: literature revue and proposed guidelines. J Clin Epidemiol 1993, 46: 1417–32. 10.1016/0895-4356(93)90142-NCrossRefPubMed Guillemin F, Bombardier C, Beaton D: Cross-cultural adaptation of health-related quality of life measures: literature revue and proposed guidelines. J Clin Epidemiol 1993, 46: 1417–32. 10.1016/0895-4356(93)90142-NCrossRefPubMed
27.
go back to reference Beaton D, Bombardier C, Guillemin F, Ferraz MB: Guidelines for the process of cross-cultural adaptation of self-report measures. Spine 2000, 25: 3186–91. 10.1097/00007632-200012150-00014CrossRefPubMed Beaton D, Bombardier C, Guillemin F, Ferraz MB: Guidelines for the process of cross-cultural adaptation of self-report measures. Spine 2000, 25: 3186–91. 10.1097/00007632-200012150-00014CrossRefPubMed
28.
go back to reference Cronbach LJ: Coefficient alpha and the internal structure of tests. Psychometrika 1951, 16: 297–334. 10.1007/BF02310555CrossRef Cronbach LJ: Coefficient alpha and the internal structure of tests. Psychometrika 1951, 16: 297–334. 10.1007/BF02310555CrossRef
29.
go back to reference Leplège A, Coste J: Mesure de la santé perceptuelle et de la qualité de vie: méthodes et applications. Paris: Estem; 2001. Leplège A, Coste J: Mesure de la santé perceptuelle et de la qualité de vie: méthodes et applications. Paris: Estem; 2001.
30.
go back to reference Salaffi F, Malavolta N, Cimmino MA, Di Matteo L, Scendoni P, Carotti M, Stancati A, Mulé R, Frigato M, Gutierrez M, Grassi W, Italian Multicentre Osteoporotic Fracture (IMOF) Study Group: Validity and reliability of the Italian version of the ECOS-16 questionnaire in post-menopausal women with prevalent vertebral fractures due to osteoporosis. Clin Exp Rheumatol 2007, 25: 390–403.PubMed Salaffi F, Malavolta N, Cimmino MA, Di Matteo L, Scendoni P, Carotti M, Stancati A, Mulé R, Frigato M, Gutierrez M, Grassi W, Italian Multicentre Osteoporotic Fracture (IMOF) Study Group: Validity and reliability of the Italian version of the ECOS-16 questionnaire in post-menopausal women with prevalent vertebral fractures due to osteoporosis. Clin Exp Rheumatol 2007, 25: 390–403.PubMed
31.
go back to reference Adachi JD, Loannidis G, Berger C, Joseph L, Papaioannou A, Pickard L, Papadimitropoulos EA, Hopman W, Poliquin S, Prior JC, Hanley DA, Olszynski WP, Anastassiades T, Brown JP, Murray T, Jackson SA, Tenenhouse A, Canadian Multicentre Osteoporosis Study (CaMos) Research Group: The influence of osteoporotic fractures on health-related quality of life in community-dwelling men and women across Canada. Osteoporos Int 2001, 12: 903–908. 10.1007/s001980170017CrossRefPubMed Adachi JD, Loannidis G, Berger C, Joseph L, Papaioannou A, Pickard L, Papadimitropoulos EA, Hopman W, Poliquin S, Prior JC, Hanley DA, Olszynski WP, Anastassiades T, Brown JP, Murray T, Jackson SA, Tenenhouse A, Canadian Multicentre Osteoporosis Study (CaMos) Research Group: The influence of osteoporotic fractures on health-related quality of life in community-dwelling men and women across Canada. Osteoporos Int 2001, 12: 903–908. 10.1007/s001980170017CrossRefPubMed
32.
go back to reference Burger H, van Daele PLA, Grashuis K, Hofman A, Grobbee DE, Schütte HE, Birkenhäger JC, Pols HA: Vertebral deformities and functional impairment in men and women. J Bone Miner Res 1997, 12: 152–157. 10.1359/jbmr.1997.12.1.152CrossRefPubMed Burger H, van Daele PLA, Grashuis K, Hofman A, Grobbee DE, Schütte HE, Birkenhäger JC, Pols HA: Vertebral deformities and functional impairment in men and women. J Bone Miner Res 1997, 12: 152–157. 10.1359/jbmr.1997.12.1.152CrossRefPubMed
33.
go back to reference Silverman SL: The Osteoporosis Assessment Questionnaire (OPAQ): A reliable and valid disease-targeted measure of health-related quality of life in osteoporosis. Qual Life Res 2000, 9: 764–774. 10.1023/A:1008934208764CrossRef Silverman SL: The Osteoporosis Assessment Questionnaire (OPAQ): A reliable and valid disease-targeted measure of health-related quality of life in osteoporosis. Qual Life Res 2000, 9: 764–774. 10.1023/A:1008934208764CrossRef
34.
go back to reference Fechtenbaum J, Cropet C, Kolta S, Horlait S, Orcel P, Roux C: The severity of vertebral fractures and health-related quality of life in osteoporotic post menopausal women. Osteoporos Int 2005, 16: 2175–2179. 10.1007/s00198-005-2023-0CrossRefPubMed Fechtenbaum J, Cropet C, Kolta S, Horlait S, Orcel P, Roux C: The severity of vertebral fractures and health-related quality of life in osteoporotic post menopausal women. Osteoporos Int 2005, 16: 2175–2179. 10.1007/s00198-005-2023-0CrossRefPubMed
35.
go back to reference Lips P, Cooper C, Agnusdei D, Caulin F, Egger P, Johnell O, Kanis JA, Liberman U, Minne H, Reeve J, Reginster JY, de Vernejoul MC, Wiklund I: Quality of life as outcome in the treatment of osteoporosis: the development of a questionnaire for quality of life by the European Foundation for Osteoporosis. Osteoporos Int 1997, 7: 36–38. 10.1007/BF01623457CrossRefPubMed Lips P, Cooper C, Agnusdei D, Caulin F, Egger P, Johnell O, Kanis JA, Liberman U, Minne H, Reeve J, Reginster JY, de Vernejoul MC, Wiklund I: Quality of life as outcome in the treatment of osteoporosis: the development of a questionnaire for quality of life by the European Foundation for Osteoporosis. Osteoporos Int 1997, 7: 36–38. 10.1007/BF01623457CrossRefPubMed
36.
go back to reference Creamer P, Lethbridge-Cejku M, Hochberg MC: Determinants of pain severity in knee osteoarthritis: effect of demographic and psychosocial variables using 3 pain measures. J Rheumatol 1999, 26: 1785–1792.PubMed Creamer P, Lethbridge-Cejku M, Hochberg MC: Determinants of pain severity in knee osteoarthritis: effect of demographic and psychosocial variables using 3 pain measures. J Rheumatol 1999, 26: 1785–1792.PubMed
37.
go back to reference Taft LB, Looker PA, Cella D: Osteoporosis: a disease management opportunity. Orthop Nurs 2000, 19: 67–76. 10.1097/00006416-200019020-00010CrossRefPubMed Taft LB, Looker PA, Cella D: Osteoporosis: a disease management opportunity. Orthop Nurs 2000, 19: 67–76. 10.1097/00006416-200019020-00010CrossRefPubMed
Metadata
Title
Factors influencing quality of life in Moroccan postmenopausal women with osteoporotic vertebral fracture assessed by ECOS 16 questionnaire
Authors
Fatima E Abourazzak
Fadoua Allali
Samira Rostom
Ihsane Hmamouchi
Linda Ichchou
Laila El Mansouri
Loubna Bennani
Hamza Khazzani
Redouane Abouqal
Najia Hajjaj-Hassouni
Publication date
01-12-2009
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2009
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/1477-7525-7-23

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