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Health and Quality of Life Outcomes
Published in: Health and Quality of Life Outcomes 1/2012

Open Access 01-12-2012 | Research

Validity and reliability of the Iranian version of the Pediatric Quality of Life Inventory™ 4.0 (PedsQL™) Generic Core Scales in children

Authors: Parisa Amiri, Ghazaleh Eslamian, Parvin Mirmiran, Niloofar Shiva, Mohammad Asghari Jafarabadi, Fereidoun Azizi

Published in: Health and Quality of Life Outcomes | Issue 1/2012

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Abstract

Background

This study aimed to investigate the reliability and validity of the Iranian version of the Pediatric Quality of Life Inventory™ 4.0 (PedsQL™ 4.0) Generic Core Scales in children.

Methods

A standard forward and backward translation procedure was used to translate the US English version of the PedsQL™ 4.0 Generic Core Scales for children into the Iranian language (Persian). The Iranian version of the PedsQL™ 4.0 Generic Core Scales was completed by 503 healthy and 22 chronically ill children aged 8-12 years and their parents. The reliability was evaluated using internal consistency. Known-groups discriminant comparisons were made, and exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were conducted.

Results

The internal consistency, as measured by Cronbach's alpha coefficients, exceeded the minimum reliability standard of 0.70. All monotrait-multimethod correlations were higher than multitrait-multimethod correlations. The intraclass correlation coefficients (ICC) between the children self-report and parent proxy-reports showed moderate to high agreement. Exploratory factor analysis extracted six factors from the PedsQL™ 4.0 for both self and proxy reports, accounting for 47.9% and 54.8% of total variance, respectively. The results of the confirmatory factor analysis for 6-factor models for both self-report and proxy-report indicated acceptable fit for the proposed models. Regarding health status, as hypothesized from previous studies, healthy children reported significantly higher health-related quality of life than those with chronic illnesses.

Conclusions

The findings support the initial reliability and validity of the Iranian version of the PedsQL™ 4.0 as a generic instrument to measure health-related quality of life of children in Iran.
Appendix
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Literature
1.
Spilker B: Quality of life and pharmacoeconomics in clinical trials. 2nd edition. Philadelphia: Lippincott-Raven; 1996.
2.
Zahran HS, Kobau R, Moriarty DG, Zack MM, Holt J, Donehoo R: Health-related quality of life surveillance--United States, 1993–2002. MMWR Surveillance summaries: Morbidity and mortality weekly report Surveillance summaries/CDC 2005, 54(4):1–35.
3.
Ganz PA: Impact of quality of life outcomes on clinical practice. Oncology (Williston Park) 1995, 9(11 Suppl):61–65.
4.
Fayers PM, Machin D: Quality of life: the assessment, analysis, and interpretation of patient-reported outcomes. 2nd edition. Chichester, Hoboken, NJ: J. Wiley; 2007.CrossRef
5.
Pal DK: Quality of life assessment in children: a review of conceptual and methodological issues in multidimensional health status measures. Journal of epidemiology and community health 1996, 50(4):391–396. 10.1136/jech.50.4.391PubMedCentralCrossRefPubMed
6.
World Health Organization: Constitution of the World Health Organization: Basic document. Geneva, Switzerland. 1948.
7.
Varni JW, Burwinkle TM, Limbers CA, Szer IS: The PedsQL as a patient-reported outcome in children and adolescents with fibromyalgia: an analysis of OMERACT domains. Health and quality of life outcomes 2007, 5: 9. 10.1186/1477-7525-5-9PubMedCentralCrossRefPubMed
8.
Varni JW, Seid M, Kurtin PS: PedsQL 4.0: reliability and validity of the Pediatric Quality of Life Inventory version 4.0 generic core scales in healthy and patient populations. Medical care 2001, 39(8):800–812. 10.1097/00005650-200108000-00006CrossRefPubMed
9.
Felder-Puig R, Baumgartner M, Topf R, Gadner H, Formann AK: Health-related quality of life in Austrian elementary school children. Medical care 2008, 46(4):432–439. 10.1097/MLR.0b013e3181648e95CrossRefPubMed
10.
Varni JW, Burwinkle TM, Seid M, Skarr D: The PedsQL 4.0 as a pediatric population health measure: feasibility, reliability, and validity. Ambulatory pediatrics: the official journal of the Ambulatory Pediatric Association 2003, 3(6):329–341. 10.1367/1539-4409(2003)003<0329:TPAAPP>2.0.CO;2CrossRef
11.
Mistry RD, Stevens MW, Gorelick MH: Health-related quality of life for pediatric emergency department febrile illnesses: an evaluation of the Pediatric Quality of Life Inventory 4.0 Generic Core Scales. Health and quality of life outcomes 2009, 7: 5. 10.1186/1477-7525-7-5PubMedCentralCrossRefPubMed
12.
Varni JW, Burwinkle TM, Katz ER, Meeske K, Dickinson P: The PedsQL in pediatric cancer: reliability and validity of the Pediatric Quality of Life Inventory Generic Core Scales, Multidimensional Fatigue Scale, and Cancer Module. Cancer 2002, 94(7):2090–2106. 10.1002/cncr.10428CrossRefPubMed
13.
Varni JW, Burwinkle TM, Berrin SJ, Sherman SA, Artavia K, Malcarne VL, Chambers HG: The PedsQL in pediatric cerebral palsy: reliability, validity, and sensitivity of the Generic Core Scales and Cerebral Palsy Module. Developmental medicine and child neurology 2006, 48(6):442–449. 10.1017/S001216220600096XCrossRefPubMed
14.
Varni JW, Limbers CA, Bryant WP, Wilson DP: The PedsQL Multidimensional Fatigue Scale in type 1 diabetes: feasibility, reliability, and validity. Pediatric diabetes 2009, 10(5):321–328. 10.1111/j.1399-5448.2008.00482.xCrossRefPubMed
15.
Varni JW, Seid M, Smith Knight T, Burwinkle T, Brown J, Szer IS: The PedsQL in pediatric rheumatology: reliability, validity, and responsiveness of the Pediatric Quality of Life Inventory Generic Core Scales and Rheumatology Module. Arthritis and rheumatism 2002, 46(3):714–725. 10.1002/art.10095CrossRefPubMed
16.
Goldstein SL, Rosburg NM, Warady BA, Seikaly M, McDonald R, Limbers C, Varni JW: Pediatric end stage renal disease health-related quality of life differs by modality: a PedsQL ESRD analysis. Pediatr Nephrol 2009, 24(8):1553–1560. 10.1007/s00467-009-1174-1CrossRefPubMed
17.
Chen X, Origasa H, Ichida F, Kamibeppu K, Varni JW: Reliability and validity of the Pediatric Quality of Life Inventory (PedsQL) Short Form 15 Generic Core Scales in Japan. Quality of life research: an international journal of quality of life aspects of treatment, care and rehabilitation 2007, 16(7):1239–1249. 10.1007/s11136-007-9230-4CrossRef
18.
Gkoltsiou K, Dimitrakaki C, Tzavara C, Papaevangelou V, Varni JW, Tountas Y: Measuring health-related quality of life in Greek children: psychometric properties of the Greek version of the Pediatric Quality of Life Inventory(TM) 4.0 Generic Core Scales. Quality of life research: an international journal of quality of life aspects of treatment, care and rehabilitation 2008, 17(2):299–305. 10.1007/s11136-007-9294-1CrossRef
19.
Reinfjell T, Diseth TH, Veenstra M, Vikan A: Measuring health-related quality of life in young adolescents: reliability and validity in the Norwegian version of the Pediatric Quality of Life Inventory 4.0 (PedsQL) generic core scales. Health and quality of life outcomes 2006, 4: 61. 10.1186/1477-7525-4-61PubMedCentralCrossRefPubMed
20.
Berkes A, Pataki I, Kiss M, Kemeny C, Kardos L, Varni JW, Mogyorosy G: Measuring health-related quality of life in Hungarian children with heart disease: psychometric properties of the Hungarian version of the Pediatric Quality of Life Inventory 4.0 Generic Core Scales and the Cardiac Module. Health and quality of life outcomes 2010, 8: 14. 10.1186/1477-7525-8-14PubMedCentralCrossRefPubMed
21.
Hetherington EM, Lerner RM, Perlmutter M, Social Science Research Council (U.S.): Child development in life-span perspective. Hillsdale, N.J: Lawrence Erlbaum Associates; 1988.
22.
Amiri P, MA E, Jalali-Farahani S, Hosseinpanah F, Varni JW, Ghofranipour F, Montazeri A, Azizi F: Reliability and validity of the Iranian version of the Pediatric Quality of Life Inventory 4.0 Generic Core Scales in adolescents. Quality of life research: an international journal of quality of life aspects of treatment, care and rehabilitation 2010, 19(10):1501–1508. 10.1007/s11136-010-9712-7CrossRef
23.
Jafari P, Ghanizadeh A, Akhondzadeh S, Mohammadi MR: Health-related quality of life of Iranian children with attention deficit/hyperactivity disorder. Quality of life research: an international journal of quality of life aspects of treatment, care and rehabilitation 2011, 20(1):31–36. 10.1007/s11136-010-9722-5CrossRef
24.
25.
Chou C-P, Bentler PM: Estimates and tests in structural equation modeling. In Structural equation modeling: Concepts, issues, and applications. Edited by: Hoyle RH. Thousand Oaks, CA, US: Sage Publications, Inc; 1995:37–55.
26.
Kline RB: Principles and practice of structural equation modeling. 2nd edition. New York: Guilford Press; 2005.
27.
McHorney CA, Ware JE Jr, Lu JF, Sherbourne CD: The MOS 36-item Short-Form Health Survey (SF-36): III. Tests of data quality, scaling assumptions, and reliability across diverse patient groups. Medical care 1994, 32(1):40–66. 10.1097/00005650-199401000-00004CrossRefPubMed
28.
McHorney CA, Tarlov AR: Individual-patient monitoring in clinical practice: are available health status surveys adequate? Quality of life research: an international journal of quality of life aspects of treatment, care and rehabilitation 1995, 4(4):293–307. 10.1007/BF01593882CrossRef
29.
Cronbach L: Coefficient alpha and the internal structure of tests. Psychometrika 1951, 16(3):297–334. 10.1007/BF02310555CrossRef
30.
Bartko JJ: The intraclass correlation coefficient as a measure of reliability. Psychological reports 1966, 19(1):3–11. 10.2466/pr0.1966.19.1.3CrossRefPubMed
31.
Cohen J: Statistical power analysis for the behavioral sciences. 2nd edition. Hillsdale, N.J: L. Erlbaum Associates; 1988.
32.
Bentler PM, Bonett DG: Significance tests and goodness of fit in the analysis of covariance structures. Psychological Bulletin 1980, 88(3):588–606.CrossRef
33.
Limbers CA, Newman DA, Varni JW: Factorial invariance of child self-report across healthy and chronic health condition groups: a confirmatory factor analysis utilizing the PedsQLTM 4.0 Generic Core Scales. Journal of pediatric psychology 2008, 33(6):630–639.CrossRefPubMed
34.
Varni JW, Limbers C, Newman D: Factorial Invariance of the PedsQL™ 4.0 Generic Core Scales Child Self-Report Across Gender: A Multigroup Confirmatory Factor Analysis with 11,356 Children Ages 5 to 18. Applied Research in Quality of Life 2008, 3(2):137–148. 10.1007/s11482-008-9051-9CrossRef
35.
Limbers CA, Newman DA, Varni JW: Factorial invariance of child self-report across age subgroups: a confirmatory factor analysis of ages 5 to 16 years utilizing the PedsQL 4.0 Generic Core Scales. Value in health: the journal of the International Society for Pharmacoeconomics and Outcomes Research 2008, 11(4):659–668. 10.1111/j.1524-4733.2007.00289.xCrossRef
36.
Upton P, Eiser C, Cheung I, Hutchings HA, Jenney M, Maddocks A, Russell IT, Williams JG: Measurement properties of the UK-English version of the Pediatric Quality of Life Inventory 4.0 (PedsQL) generic core scales. Health and quality of life outcomes 2005, 3: 22. 10.1186/1477-7525-3-22PubMedCentralCrossRefPubMed
37.
Scarpelli AC, Paiva SM, Pordeus IA, Ramos-Jorge ML, Varni JW, Allison PJ: Measurement properties of the Brazilian version of the Pediatric Quality of Life Inventory (PedsQL) cancer module scale. Health and quality of life outcomes 2008, 6: 7. 10.1186/1477-7525-6-7PubMedCentralCrossRefPubMed
38.
Cremeens J, Eiser C, Blades M: Factors influencing agreement between child self-report and parent proxy-reports on the Pediatric Quality of Life Inventory 4.0 (PedsQL) generic core scales. Health and quality of life outcomes 2006, 4: 58. 10.1186/1477-7525-4-58PubMedCentralCrossRefPubMed
39.
Pakpour AH, Yekaninejad MS, Zarei F, Hashemi F, Steele MM, Varni JW: The PedsQL Oral Health Scale in Iranian children: reliability and validity. International journal of paediatric dentistry/the British Paedodontic Society [and] the International Association of Dentistry for Children 21(5):342–352.
40.
Bisegger C, Cloetta B, von Rueden U, Abel T, Ravens-Sieberer U: Health-related quality of life: gender differences in childhood and adolescence. Sozial- und Praventivmedizin 2005, 50(5):281–291. 10.1007/s00038-005-4094-2CrossRefPubMed
41.
Eiser C, Morse R: A review of measures of quality of life for children with chronic illness. Archives of disease in childhood 2001, 84(3):205–211. 10.1136/adc.84.3.205PubMedCentralCrossRefPubMed
42.
Varni JW, Burwinkle TM, Jacobs JR, Gottschalk M, Kaufman F, Jones KL: The PedsQL™ in Type 1 and Type 2 Diabetes. Diabetes care 2003, 26(3):631–637. 10.2337/diacare.26.3.631CrossRefPubMed
Metadata
Title
Validity and reliability of the Iranian version of the Pediatric Quality of Life Inventory™ 4.0 (PedsQL™) Generic Core Scales in children
Authors
Parisa Amiri
Ghazaleh Eslamian
Parvin Mirmiran
Niloofar Shiva
Mohammad Asghari Jafarabadi
Fereidoun Azizi
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2012
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/1477-7525-10-3

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