Published in:
Open Access
01-08-2013 | Poster presentation
Preclinical animal models of COPD
Author:
Ross Vlahos
Published in:
Journal of Inflammation
|
Special Issue 1/2013
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Excerpt
COPD is a complex inflammatory airway disease characterized by airflow limitation that is not fully reversible. The mechanisms and mediators that drive the induction and progression of chronic inflammation, emphysema and altered lung function are poorly understood. Current treatments have limited efficacy in COPD and there is a clear need for new therapies that can prevent the induction and progression of COPD. Animal modeling systems that accurately reflect disease pathophysiology continue to be essential to the development of new therapies. …