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Cardiovascular Ultrasound
Published in: Cardiovascular Ultrasound 1/2013

Open Access 01-12-2013 | Research

Parallel improvement of left ventricular geometry and filling pressure after transcatheter aortic valve implantation in high risk aortic stenosis: comparison with major prosthetic surgery by standard echo Doppler evaluation

Authors: Marco Fabio Costantino, Maurizio Galderisi, Ernesta Dores, Pasquale Innelli, Giandomenico Tarsia, Maurilio Di Natale, Ciro Santoro, Francesco De Stefano, Roberta Esposito, Giovanni de Simone

Published in: Cardiovascular Ultrasound | Issue 1/2013

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Abstract

Purpose

The effect of Transcatheter Aortic Valve Implantation (TAVI) on left ventricular (LV) geometry and function was compared to traditional aortic replacement (AVR) by major surgery.

Methods

45 patients with aortic stenosis (AS) undergoing TAVI and 33 AVR were assessed by standard echo Doppler the day before and 2 months after the implantation. 2D echocardiograms were performed to measure left ventricular (LV) mass index (LVMi), relative wall thickness (RWT), ejection fraction (EF) and the ratio between transmitral E velocity and early diastolic velocity of mitral annulus (E/e’ ratio). Valvular-arterial impedance (Zva) was also calculated.

Results

At baseline, the 2 groups were comparable for blood pressure, heart rate, body mass index mean transvalvular gradient and aortic valve area. TAVI patients were older (p<0.0001) and had greater LVMi (p<0.005) than AVR group. After 2 months, both the procedures induced a significant reduction of transvalvular gradient and Zva but the decrease of LVMi and RWT was significant greater after TAVI (both p<0.0001). E/e’ ratio and EF were significantly improved after both the procedure but E/e’ reduction was greater after TAVI (p<0.0001). TAVI exhibited greater percent reduction in mean transvalvular gradient (p<0.05), Zva (p<0.02), LVMi (p<0.0001), RWT (p<0.0001) and E/e’ ratio (p<0.0001) than AVR patients. Reduction of E/e’ ratio was positively related with reduction of RWT (r = 0.46, p<0.002) only in TAVI group, even after adjusting for age and percent reduction of Zva (r =0.43, p<0.005).

Conclusions

TAVI induces a greater improvement of estimated LV filling pressure in comparison with major prosthetic surgery, due to more pronounced recovery of LV geometry, independent on age and changes of hemodynamic load.
Appendix
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Literature
1.
Carabello BA, Paulus WJ: Aortic stenosis. Lancet. 2009, 373: 956-966. 10.1016/S0140-6736(09)60211-7.CrossRefPubMed
2.
Villari B, Hess OM, Kaufmann P, Krogmann ON, Grimm J, Krayenbuehl HP: Effect of aortic valve stenosis (pressure overload) and regurgitation (volume overload) on left ventricular systolic and diastolic function. Am J Cardiol. 1992, 69: 927-934. 10.1016/0002-9149(92)90795-Z.CrossRefPubMed
3.
Cramariuc D, Rieck AE, Staal EM, Wachtell K, Eriksen E, Rossebø AB, Gerdts E: Factors influencing left ventricular structure and stress-corrected systolic function in men and women with asymptomatic aortic valve stenosis (a SEAS Substudy). Am J Cardiol. 2008, 101: 510-515. 10.1016/j.amjcard.2007.09.100.CrossRefPubMed
4.
Lund O, Flø C, Jensen FT, Emmertsen K, Nielsen TT, Rasmussen BS, Hansen OK, Nielsen TT, Emmertsen K, Jensen FT, Flø C, Rasmussen BS, Pilegaard HK: Left ventricular systolic and diastolic function in aortic stenosis. Eur Heart J. 1997, 18: 1977-1987. 10.1093/oxfordjournals.eurheartj.a015209.CrossRefPubMed
5.
Lancellotti P, Magne J, Donal E, Davin L, O'Connor K, Rosca M, Szymanski C, Cosyns B, Piérard LA: Clinical outcome in asymptomatic severe aortic stenosis: insights from the new proposed aortic stenosis grading classification. J Am Coll Cardiol. 2012, 59: 235-243. 10.1016/j.jacc.2011.08.072.CrossRefPubMed
6.
Holme I, Pedersen TR, Boman K, Egstrup K, Gerdts E, Kesäniemi YA, Malbecq W, Ray S, Rossebø AB, Wachtell K, Willenheimer R, Gohlke-Bärwolf C: A risk score for predicting mortality in patients with asymptomatic mild to moderate aortic stenosis. Heart. 2012, 98: 377-383. 10.1136/heartjnl-2011-300475.CrossRefPubMed
7.
Nkomo VT, Gardin JM, Skelton TN, Gottdiener JS, Scott CG, Enriquez-Sarano M: Burden of valvular heart diseases: a population-based study. Lancet. 2006, 368: 1005-1011. 10.1016/S0140-6736(06)69208-8.CrossRefPubMed
8.
Grube E, Laborde JC, Zickmann B, Gerckens U, Felderhoff T, Sauren B, Bootsveld A, Buellesfeld L, Iversen S: First report on a human percutaneous transluminal implantation of a self-expanding valve prosthesis for interventional treatment of aortic valve stenosis. Catheter Cardiovasc Interv. 2005, 66: 465-469. 10.1002/ccd.20544.CrossRefPubMed
9.
Cribier A, Eltchaninoff H, Bash A, Borenstein N, Tron C, Bauer F, Derumeaux G, Anselme F, Laborde F, Leon MB: Percutaneous transcatheter implantation of an aortic valve prosthesis for calcific aortic stenosis: first human case description. Circulation. 2002, 106: 3006-3008. 10.1161/01.CIR.0000047200.36165.B8.CrossRefPubMed
10.
Grube E, Laborde JC, Gerckens U, Felderhoff T, Sauren B, Buellesfeld L, Mueller R, Menichelli M, Schmidt T, Zickmann B, Iversen S, Stone GW: Percutaneous implantation of the Core Valve self-expanding valve prosthesis in high risk patients with aortic valve disease: the Siegburg first-in-man study. Circulation. 2006, 114: 1616-1624. 10.1161/CIRCULATIONAHA.106.639450.CrossRefPubMed
11.
Grube E, Buellesfeld L, Mueller R, Sauren B, Zickmann B, Nair D, Beucher H, Felderhoff T, Iversen S, Gerckens U: Progress and current status of percutaneous aortic valve replacement: results of three device generations of the Core Valve Revalving system. Circ Cardiovasc Interv. 2008, 1: 167-175. 10.1161/CIRCINTERVENTIONS.108.819839.CrossRefPubMed
12.
Lefèvre T, Kappetein AP, Wolner E, Nataf P, Thomas M, Schächinger V, De Bruyne B, Eltchaninoff H, Thielmann M, Himbert D, Romano M, Serruys P, Wimmer-Greinecker G, PARTNER EU Investigator Group: One year follow-up of the multi-centre European PARTNER transcatheter heart valve study. Eur Heart J. 2011, 32: 148-157. 10.1093/eurheartj/ehq427.CrossRefPubMed
13.
Eltchaninoff H, Prat A, Gilard M, Leguerrier A, Blanchard D, Fournial G, Donzeau-Gouge P, Tribouilloy C, Debrux JL, Pavie A, Gueret P, Registry Investigators: Transcatheter aortic valve implantation: early results of the FRANCE (French Aortic National Core Valve and Edwards) registry. Eur Heart J. 2011, 32: 191-197. 10.1093/eurheartj/ehq261.CrossRefPubMed
14.
Zahn R, Gerckens U, Grube E, Linke A, Sievert H, Eggebrecht H, Sack S, Hauptmann KE, Richardt G, Figulla HR, Senges J, German Transcatheter Aortic Valve Interventions-Registry Investigators: Transcatheter aortic valve implantation: first results from a multi-centre real-world registry. Eur Heart J. 2011, 32: 198-204. 10.1093/eurheartj/ehq339.CrossRefPubMed
15.
Van Mieghem NM, Chieffo A, Dumonteil N, Tchetche D, van der Boon RM, Buchanan GL, Marcheix B, Vahdat O, Serruys PW, Fajadet J, Carrié D, Colombo A, de Jaegere PP: Trends in outcome after transfemoral transcatheter aortic valve implantation. Am Heart J. 2013, 165: 183-192. 10.1016/j.ahj.2012.11.002.CrossRefPubMed
16.
Lichtenstein SV, Cheung A, Ye J, Thompson CR, Carere RG, Pasupati S, Webb JG: Transapical transcatheter aortic valve implantation in humans: initial clinical experience. Circulation. 2006, 114: 591-596. 10.1161/CIRCULATIONAHA.106.632927.CrossRefPubMed
17.
Smith CR, Leon MB, Mack MJ, Miller DC, Moses JW, Svensson LG, Tuzcu EM, Webb JG, Fontana GP, Makkar RR, Williams M, Dewey T, Kapadia S, Babaliaros V, Thourani VH, Corso P, Pichard AD, Bavaria JE, Herrmann HC, Akin JJ, Anderson WN, Wang D, Pocock SJ, PARTNER Trial Investigators: Transcatheter versus surgical aortic-valve replacement in high-risk patients. N Engl J Med. 2011, 364: 2187-2198. 10.1056/NEJMoa1103510.CrossRefPubMed
18.
Bleiziffer S, Ruge H, Mazzitelli D, Hutter A, Opitz A, Bauernschmitt R, Lange R: Survival after transapical and transfemoral aortic valve implantation: talking about two different patient populations. J Thorac Cardiovasc Surg. 2009, 138: 1073-1080. 10.1016/j.jtcvs.2009.07.031.CrossRefPubMed
19.
Walther T, Schuler G, Borger MA, Kempfert J, Seeburger J, Rückert Y, Ender J, Linke A, Scholz M, Falk V, Mohr FW: Transapical aortic valve implantation in 100 consecutive patients: comparison to propensity matched conventional aortic valve replacement. Eur Heart J. 2010, 31: 1398-1403. 10.1093/eurheartj/ehq060.CrossRefPubMed
20.
Rodés-Cabau J, Webb JG, Cheung A, Ye J, Dumont E, Feindel CM, Osten M, Natarajan MK, Velianou JL, Martucci G, DeVarennes B, Chisholm R, Peterson MD, Lichtenstein SV, Nietlispach F, Doyle D, DeLarochellière R, Teoh K, Chu V, Dancea A, Lachapelle K, Cheema A, Latter D, Horlick E: Transcatheter aortic valve implantation for the treatment of severe symptomatic aortic stenosis in patients at very high or prohibitive surgical risk: acute and late outcomes of the multicenter Canadian experience. J Am Coll Cardiol. 2010, 55: 1080-1090. 10.1016/j.jacc.2009.12.014.CrossRefPubMed
21.
Tamburino C, Capodanno D, Ramondo A, Petronio AS, Ettori F, Santoro G, Klugmann S, Bedogni F, Maisano F, Marzocchi A, Poli A, Antoniucci D, Napodano M, De Carlo M, Fiorina C, Ussia GP: Incidence and predictors of early and late mortality after transcatheter aortic valve implantation in 663 patients with severe aortic stenosis. Circulation. 2011, 123: 299-308. 10.1161/CIRCULATIONAHA.110.946533.CrossRefPubMed
22.
Pasic M, Unbehaun A, Dreysse S, Drews T, Buz S, Kukucka M, Mladenow A, Gromann T, Hetzer R: Transapical aortic valve implantation in 175 consecutive patients, excellent outcome in very high-risk patients. J Am Coll Cardiol. 2010, 56: 813-820. 10.1016/j.jacc.2010.02.065.CrossRefPubMed
23.
Grube E, Schuler G, Buellesfeld L, Gerckens U, Linke A, Wenaweser P, Sauren B, Mohr FW, Walther T, Zickmann B, Iversen S, Felderhoff T, Cartier R, Bonan R: Percutaneous aortic valve replacement for severe aortic stenosis in high-risk patients using the second- and current third-generation self-expanding CoreValve prosthesis: device success and 30-day clinical outcome. J Am Coll Cardiol. 2007, 50: 69-76. 10.1016/j.jacc.2007.04.047.CrossRefPubMed
24.
Clavel MA, Webb JG, Pibarot P, Altwegg L, Dumont E, Thompson C, De Larochellière R, Doyle D, Masson JB, Bergeron S, Bertrand OF, Rodés-Cabau J: Comparison of the hemodynamic performance of percutaneous and surgical bioprostheses for the treatment of severe aortic stenosis. J Am Coll Cardiol. 2009, 53: 1883-1991. 10.1016/j.jacc.2009.01.060.CrossRefPubMed
25.
Gonçalves A, Marcos-Alberca P, Almeria C, Feltes G, Rodríguez E, Hernández-Antolín RA, Garcia E, Maroto L, Fernandez Perez C, Silva Cardoso JC, Macaya C, Zamorano JL: Acute left ventricle diastolic function improvement after transcatheter aortic valve implantation. Eur J Echocardiogr. 2011, 12: 790-797. 10.1093/ejechocard/jer147.CrossRefPubMed
26.
Giannini C, Petronio AS, Talini E, De Carlo M, Guarracino F, Grazia M, Donne D, Nardi C, Conte L, Barletta V, Marzilli M, Di Bello V: Early and late improvement of global and regional left ventricular function after transcatheter aortic valve implantation in patients with severe aortic stenosis: an echocardiographic study. Am J Cardiovasc Dis. 2011, 1: 264-273.PubMedPubMedCentral
27.
Vizzardi E, D'Aloia A, Fiorina C, Bugatti S, Parrinello G, De Carlo M, Giannini C, Di Bello V, Petronio AS, Curello S, Ettori F, Dei CL: Early regression of left ventricular mass associated with diastolic improvement after transcatheter aortic valve implantation. J Am Soc Echocardiogr. 2012, 25: 1091-1098. 10.1016/j.echo.2012.06.010.CrossRefPubMed
28.
Spethmann S, Dreger H, Baldenhofer G, Stüer K, Saghabalyan D, Müller E, Hättasch R, Stangl V, Laule M, Baumann G, Stangl K, Knebel F: Short-term effects of transcatheter aortic valve implantation on left atrial mechanics and left ventricular diastolic function. J Am Soc Echocardiogr. 2013, 26: 64-71. 10.1016/j.echo.2012.10.002.CrossRefPubMed
29.
Shroyer AL, Coombs LP, Peterson ED, Eiken MC, De Long ER, Chen A, Ferguson TB, Grover FL, Edwards FH, Society of Thoracic Surgeons: The Society of Thoracic Surgeons: 30-day operative mortality and morbidity. risk models. Ann Thorac Surg. 2003, 75: 1856-1864. 10.1016/S0003-4975(03)00179-6.CrossRefPubMed
30.
31.
Conradi L, Seiffert M, Blankenberg S, Reichenspurner H, Diemert P, Treede H: What's new in transapical aortic valve implantation: clinical experience with second generation devices. Minerva Cardioangiol. 2013, 61: 341-349.PubMed
32.
Vahanian A, Iung B, Pierard L, Dion R, Pepper J: Valvular heart disease. The ESC Textbook of Cardiovascular Medicine. Edited by: Camm AJ, Luscher TF, Serruys PW. 2009, Malden/Oxford/Victoria: Blackwell Publishing Ltd, 625-670. 2
33.
Vahanian A, Alfieri O, Andreotti F, Antunes MJ, Barón-Esquivias G, Baumgartner H, Borger MA, Carrel TP, De Bonis M, Evangelista A, Falk V, Lung B, Lancellotti P, Pierard L, Price S, Schäfers HJ, Schuler G, Stepinska J, Swedberg K, Takkenberg J, Von Oppell UO, Windecker S, Zamorano JL, Zembala M: Guidelines on the management of valvular heart disease (version2012): the Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur J Cardiothorac Surg. 2012, 42: S1-S44.CrossRefPubMed
34.
Leon MB, Smith CR, Mack M, Miller DC, Moses JW, Svensson LG, Tuzcu EM, Webb JG, Fontana GP, Makkar RR, Brown DL, Block PC, Guyton RA, Pichard AD, Bavaria JE, Herrmann HC, Douglas PS, Petersen JL, Akin JJ, Anderson WN, Wang D, Pocock S, PARTNER Trial Investigators: Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery. N Engl J Med. 2010, 363: 1597-1607. 10.1056/NEJMoa1008232.CrossRefPubMed
35.
Galderisi M, Nistri S, Mondillo S, Losi MA, Innelli P, Mele D, Muraru D, D'Andrea A, Ballo P, Sgalambro A, Esposito R, Marti G, Santoro A, Agricola E, Badano LP, Marchioli R, Filardi PP, Mercuro G, Marino PN, Working Group of Echocardiography, Italian Society of Cardiology: Methodological approach for the assessment of ultrasound reproducibility of cardiac structure and function: a proposal of the study group of Echocardiography of the Italian Society of Cardiology (Ultra Cardia SIC) part I. Cardiovasc Ultrasound. 2011, 9: 26-10.1186/1476-7120-9-26.CrossRefPubMedPubMedCentral
36.
Galderisi M, Esposito R, Schiano-Lomoriello V, Santoro A, Ippolito R, Schiattarella P, Strazzullo P, de Simone G: Correlates of global area strain in native hypertensive patients: a three-dimensional speckle-tracking echocardiography study. Eur Heart J Cardiovasc Imaging. 2012, 13: 730-738. 10.1093/ehjci/jes026.CrossRefPubMed
37.
Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, Picard MH, Roman MJ, Seward J, Shanewise J, Solomon S, Spencer KT, St John Sutton M, Stewart W, American Society of Echocardiography's Nomenclature and Standards Committee:Recommendations for chamber quantification. Eur J Echocardiogr. 2006, 7: 79-108. 10.1016/j.euje.2005.12.014.CrossRefPubMed
38.
Nistri S, Galderisi M, Ballo P, Olivotto I, D’Andrea A, Pagliani L, Santoro A, Papesso B, Innelli P, Cecchi F, Mondillo S, Working Group of Echocardiography of the Italian Society of Cardiology: Determinants of echocardiographic left atrial volume: implications for normalcy. Eur J Echocardiogr. 2011, 12: 826-833. 10.1093/ejechocard/jer137.CrossRefPubMed
39.
Briand M, Dumesnil JG, Kadem L, Tongue AG, Rieu R, Garcia D, Pibarot P: Reduced systemic arterial compliance impacts significantly on left ventricular afterload and function in aortic stenosis: implications for diagnosis and treatment. J Am Coll Cardiol. 2005, 46: 291-298. 10.1016/j.jacc.2004.10.081.CrossRefPubMed
40.
O'Connor K, Magne J, Rosca M, Piérard LA, Lancellotti P: Left atrial function and remodelling in aortic stenosis. Eur J Echocardiogr. 2011, 12: 299-305. 10.1093/ejechocard/jer006.CrossRefPubMed
41.
Guarracino F, Talini E, Landoni G, Petronio S, Giannini C, Di Bello V: Effect of aortic valve surgery on left ventricular diastole assessed by echocardiography and neuroendocrine response: percutaneous versus surgical approach. J Cardiothorac Vasc Anesth. 2010, 24: 25-29. 10.1053/j.jvca.2009.09.009.CrossRefPubMed
42.
Provenchère S, Berroeta C, Reynaud C, Baron G, Poirier I, Desmonts JM, Iung B, Dehoux M, Philip I, Bénessiano J: Plasma brain natriuretic peptide and cardiac troponin I concentrations after adult cardiac surgery: association with postoperative cardiac dysfunction and 1-year mortality. Crit Care Med. 2006, 34: 995-1000. 10.1097/01.CCM.0000206110.94385.C4.CrossRefPubMed
43.
Rieck AE, Gerdts E, Lønnebakken MT, Bahlmann E, Cioffi G, Gohlke-Bärwolf C, Ray S, Cramariuc D: Global left ventricular load in asymptomatic aortic stenosis: covariates and prognostic implication (the SEAS trial). Cardiovasc Ultrasound. 2012, 10: 43-10.1186/1476-7120-10-43.CrossRefPubMedPubMedCentral
44.
Dulgheru R, Magne J, Capoulade R, Davin L, Vinereanu D, Pierard LA, Pibarot P, Lancellotti P: Impact of global hemodynamic load on exercise capacity in aortic stenosis. Int J Cardiol. 2013, Feb 27 [Epub ahead of print]
45.
Salustri A, Cerquetani E, Piccoli M, Pastena G, Posteraro A, Amici E, La Carrubba S, Bakir S, Al Mahmeed WA: Relationship between B-type natriuretic peptide levels and echocardiographic indices of left ventricular filling pressures in post-cardiac surgery patients. Cardiovasc Ultrasound. 2009, 7: 49-10.1186/1476-7120-7-49.CrossRefPubMedPubMedCentral
46.
Stevenson LW, Tillisch JH, Hamilton M, Luu M, Chelimsky-Fallick C, Moriguchi J, et al.: Importance of hemodynamic response to therapy in predicting survival with ejection fraction less than or equal to 20% secondary to ischemic or non ischemic dilated cardiomyopathy. Am J Cardiol. 1990, 66: 1348-1354. 10.1016/0002-9149(90)91166-4.CrossRefPubMed
47.
Steimle AE, Stevenson LW, Fonarow GC, Hamilton MA, Moriguchi JD: Prediction of improvement in recent onset cardiomyopathy after referral for heart transplantation. J Am Coll Cardiol. 1994, 23: 553-559. 10.1016/0735-1097(94)90735-8.CrossRefPubMed
48.
Wachtell K, Bella JN, Rokkedal J, Palmieri V, Papademetriou V, Dahlöf B, Aalto T, Gerdts E, Devereux RB: Change in diastolic left ventricular filling after one year of antihypertensive treatment: The Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) Study. Circulation. 2002, 105: 1071-1076. 10.1161/hc0902.104599.CrossRefPubMed
Metadata
Title
Parallel improvement of left ventricular geometry and filling pressure after transcatheter aortic valve implantation in high risk aortic stenosis: comparison with major prosthetic surgery by standard echo Doppler evaluation
Authors
Marco Fabio Costantino
Maurizio Galderisi
Ernesta Dores
Pasquale Innelli
Giandomenico Tarsia
Maurilio Di Natale
Ciro Santoro
Francesco De Stefano
Roberta Esposito
Giovanni de Simone
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Cardiovascular Ultrasound / Issue 1/2013
Electronic ISSN: 1476-7120
DOI
https://doi.org/10.1186/1476-7120-11-18

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