Published in:
Open Access
01-12-2010 | Oral presentation
Molecular epidemiology of force of infection in malaria
Authors:
Ingrid Felger, Sonja Schoepflin, Benson Kiniboro, Peter A Zimmerman, Ivo Mueller
Published in:
Malaria Journal
|
Special Issue 2/2010
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Excerpt
Genotyping Plasmodium falciparum parasites in longitudinal studies provided a new option to estimate force of infection (FOI). FOI, defined as the number of new P. falciparum clones acquired over time, is a molecular parameter equally suitable for describing basic malaria epidemiology and measuring outcomes of clinical trials of antimalarial interventions. We investigated the ability of molecular parameters to explain differences in the risk of P. falciparum infection and disease between wet and dry seasons, among age groups and with respect to insecticide-treated mosquito net use. …