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Published in: Malaria Journal 1/2008

Open Access 01-12-2008 | Research

Household cost of malaria overdiagnosis in rural Mozambique

Authors: Jen CC Hume, Guy Barnish, Tara Mangal, Luiz Armázio, Elizabeth Streat, Imelda Bates

Published in: Malaria Journal | Issue 1/2008

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Abstract

Background

It is estimated that over 70% of patients with suspected malaria in sub-Saharan Africa, diagnose and manage their illness at home without referral to a formal health clinic. Of those patients who do attend a formal health clinic, malaria overdiagnosis rates are estimated to range between 30–70%.

Methods

This paper details an observational cohort study documenting the number and cost of repeat consultations as a result of malaria overdiagnosis at two health care providers in a rural district of Mozambique. 535 adults and children with a clinical diagnosis of malaria were enrolled and followed over a 21 day period to assess treatment regimen, symptoms, number and cost of repeat visits to health providers in patients misdiagnosed with malaria compared to those with confirmed malaria (determined by positive bloodfilm reading).

Results

Diagnosis based solely on clinical symptoms overdiagnosed 23% of children (<16y) and 31% of adults with malaria. Symptoms persisted (p = 0.023) and new ones developed (p < 0.001) in more adults than children in the three weeks following initial presentation. Adults overdiagnosed with malaria had more repeat visits (67% v 46%, p = 0.01–0.06) compared to those with true malaria. There was no difference in costs between patients correctly or incorrectly diagnosed with malaria. Median costs over three weeks were $0.28 for those who had one visit and $0.76 for ≥ 3 visits and were proportionally highest among the poorest (p < 0.001)

Conclusion

Overdiagnosis of malaria results in a greater number of healthcare visits and associated cost for adult patients. Additionally, it is clear that the poorest individuals pay significantly more proportionally for their healthcare making it imperative that the treatment they receive is correct in order to prevent wastage of limited economic resources. Thus, investment in accurate malaria diagnosis and appropriate management at primary level is critical for improving health outcomes and reducing poverty.
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Literature
1.
go back to reference Amexo M, Tolhurst R, Barnish G, Bates I: Malaria misdiagnosis: effects on the poor and vulnerable. Lancet. 2004, 364: 1896-1898. 10.1016/S0140-6736(04)17446-1.CrossRefPubMed Amexo M, Tolhurst R, Barnish G, Bates I: Malaria misdiagnosis: effects on the poor and vulnerable. Lancet. 2004, 364: 1896-1898. 10.1016/S0140-6736(04)17446-1.CrossRefPubMed
2.
go back to reference Reyburn H, Mbatia R, Drakeley C, Carneiro I, Mwakasungula E, Mwerinde O, Saganda K, Shao J, Kitua A, Olomi R: Overdiagnosis of malaria in patients with severe febrile illness in Tanzania: a prospective study. Bmj. 2004, 329: 1212-10.1136/bmj.38251.658229.55.PubMedCentralCrossRefPubMed Reyburn H, Mbatia R, Drakeley C, Carneiro I, Mwakasungula E, Mwerinde O, Saganda K, Shao J, Kitua A, Olomi R: Overdiagnosis of malaria in patients with severe febrile illness in Tanzania: a prospective study. Bmj. 2004, 329: 1212-10.1136/bmj.38251.658229.55.PubMedCentralCrossRefPubMed
3.
go back to reference Ettling M, McFarland DA, Schultz LJ, Chitsulo L: Economic impact of malaria in Malawian households. Trop Med Parasitol. 1994, 45: 74-79.PubMed Ettling M, McFarland DA, Schultz LJ, Chitsulo L: Economic impact of malaria in Malawian households. Trop Med Parasitol. 1994, 45: 74-79.PubMed
4.
go back to reference Konradsen F, van der Hoek W, Amerasinghe PH, Amerasinghe FP, Fonseka KT: Household responses to malaria and their costs: a study from rural Sri Lanka. Trans R Soc Trop Med Hyg. 1997, 91: 127-130. 10.1016/S0035-9203(97)90194-2.CrossRefPubMed Konradsen F, van der Hoek W, Amerasinghe PH, Amerasinghe FP, Fonseka KT: Household responses to malaria and their costs: a study from rural Sri Lanka. Trans R Soc Trop Med Hyg. 1997, 91: 127-130. 10.1016/S0035-9203(97)90194-2.CrossRefPubMed
5.
go back to reference Konradsen F, van der Hoek W, Amerasinghe PH, Amerasinghe FP: Measuring the economic cost of malaria to households in Sri Lanka. Am J Trop Med Hyg. 1997, 56: 656-660.PubMed Konradsen F, van der Hoek W, Amerasinghe PH, Amerasinghe FP: Measuring the economic cost of malaria to households in Sri Lanka. Am J Trop Med Hyg. 1997, 56: 656-660.PubMed
6.
go back to reference Asenso-Okyere WK, Dzator JA: Household cost of seeking malaria care. A retrospective study of two districts in Ghana. Soc Sci Med. 1997, 45: 659-667. 10.1016/S0277-9536(96)00383-8.CrossRefPubMed Asenso-Okyere WK, Dzator JA: Household cost of seeking malaria care. A retrospective study of two districts in Ghana. Soc Sci Med. 1997, 45: 659-667. 10.1016/S0277-9536(96)00383-8.CrossRefPubMed
7.
go back to reference Njau JD, Goodman C, Kachur SP, Palmer N, Khatib RA, Abdulla S, Mills A, Bloland P: Fever treatment and household wealth: the challenge posed for rolling out combination therapy for malaria. Trop Med Int Health. 2006, 11: 299-313. 10.1111/j.1365-3156.2006.01569.x.CrossRefPubMed Njau JD, Goodman C, Kachur SP, Palmer N, Khatib RA, Abdulla S, Mills A, Bloland P: Fever treatment and household wealth: the challenge posed for rolling out combination therapy for malaria. Trop Med Int Health. 2006, 11: 299-313. 10.1111/j.1365-3156.2006.01569.x.CrossRefPubMed
8.
go back to reference Community-based solutions for effective malaria control: Lessons from Mozambique. World Relief. 2005 Community-based solutions for effective malaria control: Lessons from Mozambique. World Relief. 2005
9.
go back to reference Deaton A: The analysis of household surveys: A microeconomic approach to development policy. 1997, Baltimore MD: Published for the World Bank: The John Hopkins University PressCrossRef Deaton A: The analysis of household surveys: A microeconomic approach to development policy. 1997, Baltimore MD: Published for the World Bank: The John Hopkins University PressCrossRef
10.
go back to reference Reyburn H, Ruanda J, Mwerinde O, Drakeley C: The contribution of microscopy to targeting antimalarial treatment in a low transmission area of Tanzania. Malar J. 2006, 5: 4-10.1186/1475-2875-5-4.PubMedCentralCrossRefPubMed Reyburn H, Ruanda J, Mwerinde O, Drakeley C: The contribution of microscopy to targeting antimalarial treatment in a low transmission area of Tanzania. Malar J. 2006, 5: 4-10.1186/1475-2875-5-4.PubMedCentralCrossRefPubMed
11.
go back to reference Jowett M, Miller NJ: The financial burden of malaria in Tanzania: implications for future government policy. Int J Health Plann Manage. 2005, 20: 67-84. 10.1002/hpm.796.CrossRefPubMed Jowett M, Miller NJ: The financial burden of malaria in Tanzania: implications for future government policy. Int J Health Plann Manage. 2005, 20: 67-84. 10.1002/hpm.796.CrossRefPubMed
12.
go back to reference Goodman C: The economic evaluation of malaria diagnosis. Draft Position Paper prepared for informal consulation on "Malaria diagnostics at the turn of the century", organised by WHO and USAID, Geneva. 25–27 October 1999 Goodman C: The economic evaluation of malaria diagnosis. Draft Position Paper prepared for informal consulation on "Malaria diagnostics at the turn of the century", organised by WHO and USAID, Geneva. 25–27 October 1999
13.
go back to reference Ettling MB, Shepard DS: Economic cost of malaria in Rwanda. Trop Med Parasitol. 1991, 42: 214-218.PubMed Ettling MB, Shepard DS: Economic cost of malaria in Rwanda. Trop Med Parasitol. 1991, 42: 214-218.PubMed
14.
go back to reference Gatton ML, Cho Min N: Costs to the patient for seeking malaria care in Myanmar. Acta Trop. 2004, 92: 173-177. 10.1016/j.actatropica.2003.12.005.CrossRefPubMed Gatton ML, Cho Min N: Costs to the patient for seeking malaria care in Myanmar. Acta Trop. 2004, 92: 173-177. 10.1016/j.actatropica.2003.12.005.CrossRefPubMed
15.
go back to reference Sauerborn R, Shepard DS, Ettling MB, Brinkmann U, Nougtara A, Diesfeld HJ: Estimating the direct and indirect economic costs of malaria in a rural district of Burkina Faso. Trop Med Parasitol. 1991, 42: 219-223.PubMed Sauerborn R, Shepard DS, Ettling MB, Brinkmann U, Nougtara A, Diesfeld HJ: Estimating the direct and indirect economic costs of malaria in a rural district of Burkina Faso. Trop Med Parasitol. 1991, 42: 219-223.PubMed
16.
go back to reference Bates I, Fenton C, Gruber J, Lalloo D, Medina Lara A, Squire SB, Theobald S, Thomson R, Tolhurst R: Vulnerability to malaria, tuberculosis, and HIV/AIDS infection and disease. Part 1: determinants operating at individual and household level. Lancet Infect Dis. 2004, 4: 267-277. 10.1016/S1473-3099(04)01002-3.CrossRefPubMed Bates I, Fenton C, Gruber J, Lalloo D, Medina Lara A, Squire SB, Theobald S, Thomson R, Tolhurst R: Vulnerability to malaria, tuberculosis, and HIV/AIDS infection and disease. Part 1: determinants operating at individual and household level. Lancet Infect Dis. 2004, 4: 267-277. 10.1016/S1473-3099(04)01002-3.CrossRefPubMed
17.
go back to reference Malaria diagnosis – New perspectives. WHO/CDS/RBM/2000. 2002, Geneva: World Health Organisation, 14 Malaria diagnosis – New perspectives. WHO/CDS/RBM/2000. 2002, Geneva: World Health Organisation, 14
18.
go back to reference Essential Medical Laboratory Services Report. 2002, 1998–2002 Ministry of Health and Liverpool School of Tropical Medicine ed Essential Medical Laboratory Services Report. 2002, 1998–2002 Ministry of Health and Liverpool School of Tropical Medicine ed
Metadata
Title
Household cost of malaria overdiagnosis in rural Mozambique
Authors
Jen CC Hume
Guy Barnish
Tara Mangal
Luiz Armázio
Elizabeth Streat
Imelda Bates
Publication date
01-12-2008
Publisher
BioMed Central
Published in
Malaria Journal / Issue 1/2008
Electronic ISSN: 1475-2875
DOI
https://doi.org/10.1186/1475-2875-7-33

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