Skip to main content
Top
Published in: Malaria Journal 1/2014

Open Access 01-12-2014 | Research

Operational research on malaria control and elimination: a review of projects published between 2008 and 2013

Authors: Shui-sen Zhou, Aafje EC Rietveld, Mar Velarde-Rodriguez, Andrew R Ramsay, Shao-sen Zhang, Xiao-nong Zhou, Richard E Cibulskis

Published in: Malaria Journal | Issue 1/2014

Login to get access

Abstract

A literature review for operational research on malaria control and elimination was conducted using the term 'malaria' and the definition of operational research (OR). A total of 15 886 articles related to malaria were searched between January 2008 and June 2013. Of these, 582 (3.7%) met the definition of operational research. These OR projects had been carried out in 83 different countries. Most OR studies (77%) were implemented in Africa south of the Sahara. Only 5 (1%) of the OR studies were implemented in countries in the pre-elimination or elimination phase. The vast majority of OR projects (92%) were led by international or local research institutions, while projects led by National Malaria Control Programmes (NMCP) accounted for 7.8%. With regards to the topic under investigation, the largest percentage of papers was related to vector control (25%), followed by epidemiology/transmission (16.5%) and treatment (16.3%). Only 19 (3.8%) of the OR projects were related to malaria surveillance. Strengthening the capacity of NMCPs to conduct operational research and publish its findings, and improving linkages between NMCPs and research institutes may aid progress towards malaria elimination and eventual eradication world-wide.
Appendix
Available only for authorised users
Literature
1.
go back to reference WHO: World Malaria Report 2013. 2013, Geneva: World Health Organization WHO: World Malaria Report 2013. 2013, Geneva: World Health Organization
2.
go back to reference Zachariah R, Harries A, Ishikawa N, Rieder H, Bissell K, Laserson K, Massaquoi M, Herp M: Operational research in low-income countries: what, why, and how?. Lancet Infect Dis. 2009, 9: 711-717. 10.1016/S1473-3099(09)70229-4.CrossRefPubMed Zachariah R, Harries A, Ishikawa N, Rieder H, Bissell K, Laserson K, Massaquoi M, Herp M: Operational research in low-income countries: what, why, and how?. Lancet Infect Dis. 2009, 9: 711-717. 10.1016/S1473-3099(09)70229-4.CrossRefPubMed
3.
go back to reference Durrheim D, Speare R, Harries A: Research that influences policy and practice - characteristics of operational research to improve malaria control in Mpumalanga Province. South Africa. Malar J. 2002, 1: 9-PubMed Durrheim D, Speare R, Harries A: Research that influences policy and practice - characteristics of operational research to improve malaria control in Mpumalanga Province. South Africa. Malar J. 2002, 1: 9-PubMed
5.
go back to reference Hill J, Hoyt J, van Eijk AM, D'Mello-Guyett L, Ter Kuile FO, Steketee R, Smith H, Webster J: Factors affecting the delivery, access, and use of interventions to prevent malaria in pregnancy in sub-Saharan Africa: a systematic review and meta-analysis. PLoS Med. 2013, 10: e1001488-10.1371/journal.pmed.1001488.PubMedCentralCrossRefPubMed Hill J, Hoyt J, van Eijk AM, D'Mello-Guyett L, Ter Kuile FO, Steketee R, Smith H, Webster J: Factors affecting the delivery, access, and use of interventions to prevent malaria in pregnancy in sub-Saharan Africa: a systematic review and meta-analysis. PLoS Med. 2013, 10: e1001488-10.1371/journal.pmed.1001488.PubMedCentralCrossRefPubMed
6.
go back to reference Karunamoorthi K: Vector control: a cornerstone in the malaria elimination campaign. Clin Microbiol Infect. 2011, 17: 1608-1616. 10.1111/j.1469-0691.2011.03664.x.CrossRefPubMed Karunamoorthi K: Vector control: a cornerstone in the malaria elimination campaign. Clin Microbiol Infect. 2011, 17: 1608-1616. 10.1111/j.1469-0691.2011.03664.x.CrossRefPubMed
8.
go back to reference Kerouedan D: [The Global Fund to fight HIV/AIDS, TB and Malaria 5-y: evaluation policy issues](in French). Bull Soc Pathol Exot. 2010, 103: 119-122. 10.1007/s13149-010-0051-2.CrossRefPubMed Kerouedan D: [The Global Fund to fight HIV/AIDS, TB and Malaria 5-y: evaluation policy issues](in French). Bull Soc Pathol Exot. 2010, 103: 119-122. 10.1007/s13149-010-0051-2.CrossRefPubMed
9.
go back to reference The malERA Consultative Group on Health Systems and Operational Research: A Research Agenda for Malaria Eradication: Health Systems and Operational Research. PLoS Med. 2011, 8: e1000397-PubMedCentralCrossRef The malERA Consultative Group on Health Systems and Operational Research: A Research Agenda for Malaria Eradication: Health Systems and Operational Research. PLoS Med. 2011, 8: e1000397-PubMedCentralCrossRef
10.
go back to reference Higgins JPT, Deeks JJ: Selecting studies and collecting data. Cochrane Handbook for Systematic Reviews of Interventions. Version 510 (updated March 2011). 2011, The Cochrane Collaboration; John Wiley & Sons, Ltd, Chapter 7- Higgins JPT, Deeks JJ: Selecting studies and collecting data. Cochrane Handbook for Systematic Reviews of Interventions. Version 510 (updated March 2011). 2011, The Cochrane Collaboration; John Wiley & Sons, Ltd, Chapter 7-
11.
go back to reference Magalhães RJ, Langa A, Sousa-Figueiredo JC, Clements AC, Nery SV: Finding malaria hot-spots in northern Angola: the role of individual, household and environmental factors within a meso-endemic area. Malar J. 2012, 11: 385-10.1186/1475-2875-11-385.PubMedCentralCrossRefPubMed Magalhães RJ, Langa A, Sousa-Figueiredo JC, Clements AC, Nery SV: Finding malaria hot-spots in northern Angola: the role of individual, household and environmental factors within a meso-endemic area. Malar J. 2012, 11: 385-10.1186/1475-2875-11-385.PubMedCentralCrossRefPubMed
12.
go back to reference Srivastava A, Nagpal BN, Joshi PL, Paliwal JC, Dash AP: Identification of malaria hot spots for focused intervention in tribal state of India: a GIS based approach. Int J Health Geogr. 2009, 8: 30-10.1186/1476-072X-8-30.PubMedCentralCrossRefPubMed Srivastava A, Nagpal BN, Joshi PL, Paliwal JC, Dash AP: Identification of malaria hot spots for focused intervention in tribal state of India: a GIS based approach. Int J Health Geogr. 2009, 8: 30-10.1186/1476-072X-8-30.PubMedCentralCrossRefPubMed
13.
go back to reference Mosha JF, Sturrock HJ, Greenhouse B, Greenwood B, Sutherland CJ, Gadalla N, Atwal S, Drakeley C, Kibiki G, Bousema T, Chandramohan D, Gosling R: Epidemiology of subpatent Plasmodium falciparum infection: implications for detection of hotspots with imperfect diagnostics. Malar J. 2013, 12: 221-10.1186/1475-2875-12-221.PubMedCentralCrossRefPubMed Mosha JF, Sturrock HJ, Greenhouse B, Greenwood B, Sutherland CJ, Gadalla N, Atwal S, Drakeley C, Kibiki G, Bousema T, Chandramohan D, Gosling R: Epidemiology of subpatent Plasmodium falciparum infection: implications for detection of hotspots with imperfect diagnostics. Malar J. 2013, 12: 221-10.1186/1475-2875-12-221.PubMedCentralCrossRefPubMed
14.
go back to reference Sturrock HJ, Hsiang MS, Cohen JM, Smith DL, Greenhouse B, Bousema T, Gosling RD: Targeting asymptomatic malaria infections: active surveillance in control and elimination. PLOS Med. 2013, 10: e1001467-10.1371/journal.pmed.1001467.PubMedCentralCrossRefPubMed Sturrock HJ, Hsiang MS, Cohen JM, Smith DL, Greenhouse B, Bousema T, Gosling RD: Targeting asymptomatic malaria infections: active surveillance in control and elimination. PLOS Med. 2013, 10: e1001467-10.1371/journal.pmed.1001467.PubMedCentralCrossRefPubMed
15.
go back to reference Sturrock HJ, Novotny JM, Kunene S, Dlamini S, Zulu Z, Cohen JM, Hsiang MS, Greenhouse B, Gosling RD: Reactive case detection for malaria elimination: real-life experience from an ongoing program in Swaziland. PLoS ONE. 2013, 8: e63830-10.1371/journal.pone.0063830.PubMedCentralCrossRefPubMed Sturrock HJ, Novotny JM, Kunene S, Dlamini S, Zulu Z, Cohen JM, Hsiang MS, Greenhouse B, Gosling RD: Reactive case detection for malaria elimination: real-life experience from an ongoing program in Swaziland. PLoS ONE. 2013, 8: e63830-10.1371/journal.pone.0063830.PubMedCentralCrossRefPubMed
16.
go back to reference Diallo A, Ndam NT, Moussiliou A, Dos Santos S, Ndonky A, Borderon M, Oliveau S, Lalou R, Le Hesran JY: Asymptomatic carriage of Plasmodium in urban Dakar: the risk of malaria should not be underestimated. PLoS ONE. 2012, 7: e31100-10.1371/journal.pone.0031100.PubMedCentralCrossRefPubMed Diallo A, Ndam NT, Moussiliou A, Dos Santos S, Ndonky A, Borderon M, Oliveau S, Lalou R, Le Hesran JY: Asymptomatic carriage of Plasmodium in urban Dakar: the risk of malaria should not be underestimated. PLoS ONE. 2012, 7: e31100-10.1371/journal.pone.0031100.PubMedCentralCrossRefPubMed
17.
go back to reference Ramírez-Olivencia G, Rubio JM, Rivas P, Subirats M, Herrero MD, Lago M, Puente S: Imported submicroscopic malaria in Madrid. Malari J. 2012, 11: 324-10.1186/1475-2875-11-324.CrossRef Ramírez-Olivencia G, Rubio JM, Rivas P, Subirats M, Herrero MD, Lago M, Puente S: Imported submicroscopic malaria in Madrid. Malari J. 2012, 11: 324-10.1186/1475-2875-11-324.CrossRef
18.
go back to reference Zurovac D, Larson BA, Sudoi RK, Snow RW: Costs and cost-effectiveness of a mobile phone text-message reminder programmes to improve health workers’ adherence to malaria guidelines in Kenya. PLoS ONE. 2012, 7: e52045-10.1371/journal.pone.0052045.PubMedCentralCrossRefPubMed Zurovac D, Larson BA, Sudoi RK, Snow RW: Costs and cost-effectiveness of a mobile phone text-message reminder programmes to improve health workers’ adherence to malaria guidelines in Kenya. PLoS ONE. 2012, 7: e52045-10.1371/journal.pone.0052045.PubMedCentralCrossRefPubMed
19.
go back to reference Jones CO, Wasunna B, Sudoi R, Githinji S, Snow RW, Zurovac D: ‘Even if you know everything you can forget”: health worker perceptions of mobile phone text-messaging to improve malaria case-management in Kenya. PLoS ONE. 2012, 7: e38636-10.1371/journal.pone.0038636.PubMedCentralCrossRefPubMed Jones CO, Wasunna B, Sudoi R, Githinji S, Snow RW, Zurovac D: ‘Even if you know everything you can forget”: health worker perceptions of mobile phone text-messaging to improve malaria case-management in Kenya. PLoS ONE. 2012, 7: e38636-10.1371/journal.pone.0038636.PubMedCentralCrossRefPubMed
20.
go back to reference Otieno G, Githinji S, Jones C, Snow RW, Talisuna A, Zurovac D: The feasibility, patterns of use and acceptability of using mobile phone text-messaging to improve treatment adherence and post-treatment review of children with uncomplicated malaria in western Kenya. Malar J. 2014, 13: 44-10.1186/1475-2875-13-44.PubMedCentralCrossRefPubMed Otieno G, Githinji S, Jones C, Snow RW, Talisuna A, Zurovac D: The feasibility, patterns of use and acceptability of using mobile phone text-messaging to improve treatment adherence and post-treatment review of children with uncomplicated malaria in western Kenya. Malar J. 2014, 13: 44-10.1186/1475-2875-13-44.PubMedCentralCrossRefPubMed
21.
go back to reference Tatem AJ, Huang Z, Narib C, Kumar U, Kandula D, Pindolia DK, Smith DL, Cohen JM, Graupe B, Uusiku P, Lourenço C: Integrating rapid risk mapping and mobile phone call record data for strategic malaria elimination planning. Malar J. 2014, 13: 52-10.1186/1475-2875-13-52.PubMedCentralCrossRefPubMed Tatem AJ, Huang Z, Narib C, Kumar U, Kandula D, Pindolia DK, Smith DL, Cohen JM, Graupe B, Uusiku P, Lourenço C: Integrating rapid risk mapping and mobile phone call record data for strategic malaria elimination planning. Malar J. 2014, 13: 52-10.1186/1475-2875-13-52.PubMedCentralCrossRefPubMed
22.
go back to reference Eziefula AC, Bousema T, Yeung S, Kamya M, Owaraganise A, Gabagaya G, Bradley J, Grignard L, Lanke KH, Wanzira H, Mpimbaza A, Nsobya S, White NJ, Webb EL, Staedke SG, Drakeley C: Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: a randomised, controlled, double-blind, dose-ranging trial. Lancet Infect Dis. 2014, 14: 130-139. 10.1016/S1473-3099(13)70268-8.CrossRefPubMed Eziefula AC, Bousema T, Yeung S, Kamya M, Owaraganise A, Gabagaya G, Bradley J, Grignard L, Lanke KH, Wanzira H, Mpimbaza A, Nsobya S, White NJ, Webb EL, Staedke SG, Drakeley C: Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: a randomised, controlled, double-blind, dose-ranging trial. Lancet Infect Dis. 2014, 14: 130-139. 10.1016/S1473-3099(13)70268-8.CrossRefPubMed
Metadata
Title
Operational research on malaria control and elimination: a review of projects published between 2008 and 2013
Authors
Shui-sen Zhou
Aafje EC Rietveld
Mar Velarde-Rodriguez
Andrew R Ramsay
Shao-sen Zhang
Xiao-nong Zhou
Richard E Cibulskis
Publication date
01-12-2014
Publisher
BioMed Central
Published in
Malaria Journal / Issue 1/2014
Electronic ISSN: 1475-2875
DOI
https://doi.org/10.1186/1475-2875-13-473

Other articles of this Issue 1/2014

Malaria Journal 1/2014 Go to the issue
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.