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Open Access 01-12-2014 | Commentary

Unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: fact or artifact?

Authors: Alfredo Mendrone Jr, Crispim Cerutti Jr, José Eduardo Levi, Marcos Boulos, Maria Carmen Arroyo Sanchez, Rosely dos Santos Malafronte, Silvia Maria Di Santi, Vicente Odone Jr

Published in: Malaria Journal | Issue 1/2014

Abstract

A study searching for Plasmodium vivax and Plasmodium falciparum DNA among blood donors from the non-endemic area in Brazil reported a rate of 7.41%. This number is at least three times higher than what has been observed in blood donors from the Amazon, an endemic area concentrating >99% of all malaria cases in Brazil. Moreover, the majority of the donors were supposedly infected by P. falciparum, a rare finding both in men and anophelines from the Atlantic forest. These findings shall be taken with caution since they disagree with several publications in the literature and possibly overestimate the actual risk of malaria transmission by blood transfusion in São Paulo city.

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Title: Unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: fact or artifact?
Authors: Alfredo Mendrone Jr
Crispim Cerutti Jr
José Eduardo Levi
Marcos Boulos
Maria Carmen Arroyo Sanchez
Rosely dos Santos Malafronte
Silvia Maria Di Santi
Vicente Odone Jr
Publication date: 01-12-2014
Publisher: BioMed Central
Published in: Malaria Journal / Issue 1/2014
Electronic ISSN: 1475-2875
DOI: https://doi.org/10.1186/1475-2875-13-336

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