Skip to main content
Top
Published in: Malaria Journal 1/2013

Open Access 01-12-2013 | Research

Malaria case management in Papua New Guinea following the introduction of a revised treatment protocol

Published in: Malaria Journal | Issue 1/2013

Login to get access

Abstract

Background

This paper reports on the availability of diagnostic tools and recommended anti-malarials in the 12-month period immediately following the implementation of a new national malaria treatment protocol (NMTP) in Papua New Guinea (PNG). Health worker adherence to the new NMTP is also examined and comparisons made with previously reported pre-implementation findings.

Methods

A countrywide cross-sectional survey in randomly selected primary health care facilities (n = 88). Data were collected via passive observation of the clinical case management of fever or suspected malaria patients and via an interviewer administered questionnaire completed with the officer in charge of each participating health care facility.

Results

Malaria rapid diagnostic tests (RDTs) and the new first-line anti-malarial medication, artemether-lumefantrine (AL), were available in 53.4% and 51.1% of surveyed heath facilities, respectively. However, they were more widely available in the larger health centres as compared to the smaller aid-posts (90.2% vs. 21.3% and 87.8% vs. 19.2%, respectively). Overall, 68.3% of observed fever cases (n = 445) were tested for malaria by RDT and 39% prescribed an anti-malarial, inclusive of 98.2% of RDT positive patients and 19.8% of RDT negative cases. The availability and use of malaria RDTs was greater in the current survey as compared to pre-implementation of the new NMTP (8.9% vs. 53.4% & 16.2% vs. 68.3%, respectively) as was the availability of AL (0% vs. 51.1%). The percentage of fever patients prescribed anti-malarials decreased substantially post implementation of the new NMTP (96.4% vs. 39.0%).

Conclusions

PNG has achieved high coverage of malaria RDTs and AL at the health centre level, but these resources have yet to reach the majority of aid-posts. Malaria case management practice has substantially changed in the 12-month period immediately following the new NMTP, although full protocol adherence was rarely observed.
Literature
1.
go back to reference World Health Organization: Guidelines for the Treatment of Malaria. 2010, Geneva: WHO, 2 World Health Organization: Guidelines for the Treatment of Malaria. 2010, Geneva: WHO, 2
2.
go back to reference Papua New Guinea National Department of Health: National Malaria Treatment Protocol. 2009, Port Moresby: National Department of Health ed., 1st edition Papua New Guinea National Department of Health: National Malaria Treatment Protocol. 2009, Port Moresby: National Department of Health ed., 1st edition
3.
go back to reference Kurumop SF, Pulford J, Mueller I, Siba P, Hetzel MW: Diagnostic capacity and anti-malarial availability in Papua New Guinea prior to the introduction of a revised national malaria treatment protocol. P N G Med J. in press Kurumop SF, Pulford J, Mueller I, Siba P, Hetzel MW: Diagnostic capacity and anti-malarial availability in Papua New Guinea prior to the introduction of a revised national malaria treatment protocol. P N G Med J. in press
4.
go back to reference Pulford J, Mueller I, Siba PM, Hetzel MW: Malaria case management in Papua New Guinea prior to the introduction of a revised treatment protocol. Malar J. 2012, 11: 157-10.1186/1475-2875-11-157.PubMedCentralCrossRefPubMed Pulford J, Mueller I, Siba PM, Hetzel MW: Malaria case management in Papua New Guinea prior to the introduction of a revised treatment protocol. Malar J. 2012, 11: 157-10.1186/1475-2875-11-157.PubMedCentralCrossRefPubMed
5.
go back to reference Hetzel MW, Paul S, Benjamin L, Makita L, Mueller I, Siba PM: Proportion of fevers attributable to malaria varies significantly between sites in Papua New Guinea. P N G Med J. in press Hetzel MW, Paul S, Benjamin L, Makita L, Mueller I, Siba PM: Proportion of fevers attributable to malaria varies significantly between sites in Papua New Guinea. P N G Med J. in press
6.
go back to reference Bruxvoort K, Kalolella A, Nchimbi H, Festo C, Taylor M, Thomson R, Cairns M, Thwing J, Kleinschmidt I, Goodman C, Kachur SP: Getting antimalarials on target: impact of national roll-out of malaria rapid diagnostic tests on health facility treatment in three regions of Tanzania. Trop Med Int Health. 2013, 18: 1269-1282. 10.1111/tmi.12168.PubMedCentralCrossRefPubMed Bruxvoort K, Kalolella A, Nchimbi H, Festo C, Taylor M, Thomson R, Cairns M, Thwing J, Kleinschmidt I, Goodman C, Kachur SP: Getting antimalarials on target: impact of national roll-out of malaria rapid diagnostic tests on health facility treatment in three regions of Tanzania. Trop Med Int Health. 2013, 18: 1269-1282. 10.1111/tmi.12168.PubMedCentralCrossRefPubMed
7.
8.
go back to reference Hamer DH, Ndhlovu M, Zurovac D, Fox M, Yeboah-Antwi K, Chanda P, Sipilinyambe N, Simon JL, Snow RW: Improved diagnostic testing and malaria treatment practices in Zambia. JAMA. 2007, 297: 2227-2231. 10.1001/jama.297.20.2227.PubMedCentralCrossRefPubMed Hamer DH, Ndhlovu M, Zurovac D, Fox M, Yeboah-Antwi K, Chanda P, Sipilinyambe N, Simon JL, Snow RW: Improved diagnostic testing and malaria treatment practices in Zambia. JAMA. 2007, 297: 2227-2231. 10.1001/jama.297.20.2227.PubMedCentralCrossRefPubMed
9.
go back to reference Abdelgader TM, Ibrahim AM, Elmardi KA, Githinji S, Zurovac D, Snow RW, Noor AM: Progress towards implementation of ACT malaria case-management in public health facilities in the Republic of Sudan: a cluster-sample survey. BMC Public Health. 2012, 12: 11-10.1186/1471-2458-12-11.PubMedCentralCrossRefPubMed Abdelgader TM, Ibrahim AM, Elmardi KA, Githinji S, Zurovac D, Snow RW, Noor AM: Progress towards implementation of ACT malaria case-management in public health facilities in the Republic of Sudan: a cluster-sample survey. BMC Public Health. 2012, 12: 11-10.1186/1471-2458-12-11.PubMedCentralCrossRefPubMed
10.
go back to reference Martins JS, Zwi AB, Hobday K, Bonaparte F, Kelly PM: The implementation of a new Malaria Treatment Protocol in Timor-Leste: challenges and constraints. Health Policy Plan. 2012, 27: 677-686. 10.1093/heapol/czs019.PubMedCentralCrossRefPubMed Martins JS, Zwi AB, Hobday K, Bonaparte F, Kelly PM: The implementation of a new Malaria Treatment Protocol in Timor-Leste: challenges and constraints. Health Policy Plan. 2012, 27: 677-686. 10.1093/heapol/czs019.PubMedCentralCrossRefPubMed
11.
go back to reference WHO: World Malaria Report 2012. 2012, Geneva: World Health Organization WHO: World Malaria Report 2012. 2012, Geneva: World Health Organization
12.
go back to reference WHO: World Malaria Report 2010. 2010, Geneva: World Health Organization WHO: World Malaria Report 2010. 2010, Geneva: World Health Organization
13.
go back to reference Betuela I, Rosanas-Urgell A, Kiniboro B, Stanisic DI, Samol L, de Lazzari E, Del Portillo HA, Siba P, Alonso PL, Bassat Q, Mueller I: Relapses contribute significantly to the risk of Plasmodium vivax infection and disease in Papua New Guinean children 1–5 years of age. J Infect Dis. 2012, 206: 1771-1780. 10.1093/infdis/jis580.CrossRefPubMed Betuela I, Rosanas-Urgell A, Kiniboro B, Stanisic DI, Samol L, de Lazzari E, Del Portillo HA, Siba P, Alonso PL, Bassat Q, Mueller I: Relapses contribute significantly to the risk of Plasmodium vivax infection and disease in Papua New Guinean children 1–5 years of age. J Infect Dis. 2012, 206: 1771-1780. 10.1093/infdis/jis580.CrossRefPubMed
14.
go back to reference Hetzel MW, Pulford J, Maraga S, Barnedas C, Reimer L, Tavul L, Jamea-Maiasa S, Tandrapah A, Maalsen A, Makita L: Evaluation of the Global Fund-supported National Malaria Control Program in Papua New Guinea, 2009–2014. P N G Med J. in press Hetzel MW, Pulford J, Maraga S, Barnedas C, Reimer L, Tavul L, Jamea-Maiasa S, Tandrapah A, Maalsen A, Makita L: Evaluation of the Global Fund-supported National Malaria Control Program in Papua New Guinea, 2009–2014. P N G Med J. in press
15.
go back to reference WHO: Health Service Delivery Profile: Papua New Guinea, 2012. 2013, Geneva: World Health Organization WHO: Health Service Delivery Profile: Papua New Guinea, 2012. 2013, Geneva: World Health Organization
16.
go back to reference Hensen B, Paintain LS, Shretta R, Bruce J, Jones C, Webster J: Taking stock: provider prescribing practices in the presence and absence of ACT stock. Malar J. 2011, 10: 218-10.1186/1475-2875-10-218.PubMedCentralCrossRefPubMed Hensen B, Paintain LS, Shretta R, Bruce J, Jones C, Webster J: Taking stock: provider prescribing practices in the presence and absence of ACT stock. Malar J. 2011, 10: 218-10.1186/1475-2875-10-218.PubMedCentralCrossRefPubMed
17.
go back to reference Hetzel MW, Obrist B, Lengeler C, Msechu JJ, Nathan R, Dillip A, Makemba AM, Mshana C, Schulze A, Mshinda H: Obstacles to prompt and effective malaria treatment lead to low community-coverage in two rural districts of Tanzania. BMC Public Health. 2008, 8: 317-10.1186/1471-2458-8-317.PubMedCentralCrossRefPubMed Hetzel MW, Obrist B, Lengeler C, Msechu JJ, Nathan R, Dillip A, Makemba AM, Mshana C, Schulze A, Mshinda H: Obstacles to prompt and effective malaria treatment lead to low community-coverage in two rural districts of Tanzania. BMC Public Health. 2008, 8: 317-10.1186/1471-2458-8-317.PubMedCentralCrossRefPubMed
18.
go back to reference Macfarlane JE: A focused ethnography about treatment-seeking behaviour and traditional medicine in the Nasioi area of Bougainville. P N G Med J. 2008, 51: 29-42.PubMed Macfarlane JE: A focused ethnography about treatment-seeking behaviour and traditional medicine in the Nasioi area of Bougainville. P N G Med J. 2008, 51: 29-42.PubMed
19.
go back to reference Angwin A, Hetzel MW, Mueller I, Siba P, Pulford J: A qualitative study of how affected individuals or their caregivers respond to suspected malaria infection in rural Papua New Guinea. P N G Med J. in press Angwin A, Hetzel MW, Mueller I, Siba P, Pulford J: A qualitative study of how affected individuals or their caregivers respond to suspected malaria infection in rural Papua New Guinea. P N G Med J. in press
20.
go back to reference National Competency Training Project: Malaria Diagnosis and the New Treatment Protocol: A Training Manual for Health Workers in Papua New Guinea. 2010, Port Moresby, PNG: Birdwing Publishing National Competency Training Project: Malaria Diagnosis and the New Treatment Protocol: A Training Manual for Health Workers in Papua New Guinea. 2010, Port Moresby, PNG: Birdwing Publishing
21.
go back to reference Ansah EK, Narh-Bana S, Epokor M, Akanpigbiam S, Quartey AA, Gyapong J, Whitty CJ: Rapid testing for malaria in settings where microscopy is available and peripheral clinics where only presumptive treatment is available: a randomised controlled trial in Ghana. BMJ. 2010, 340: c930-10.1136/bmj.c930.PubMedCentralCrossRefPubMed Ansah EK, Narh-Bana S, Epokor M, Akanpigbiam S, Quartey AA, Gyapong J, Whitty CJ: Rapid testing for malaria in settings where microscopy is available and peripheral clinics where only presumptive treatment is available: a randomised controlled trial in Ghana. BMJ. 2010, 340: c930-10.1136/bmj.c930.PubMedCentralCrossRefPubMed
22.
go back to reference Kyabayinze DJ, Asiimwe C, Nakanjako D, Nabakooza J, Counihan H, Tibenderana JK: Use of RDTs to improve malaria diagnosis and fever case management at primary health care facilities in Uganda. Malar J. 2010, 9: 200-10.1186/1475-2875-9-200.PubMedCentralCrossRefPubMed Kyabayinze DJ, Asiimwe C, Nakanjako D, Nabakooza J, Counihan H, Tibenderana JK: Use of RDTs to improve malaria diagnosis and fever case management at primary health care facilities in Uganda. Malar J. 2010, 9: 200-10.1186/1475-2875-9-200.PubMedCentralCrossRefPubMed
23.
go back to reference Sudoi RK, Githinji S, Nyandigisi A, Muturi A, Snow RW, Zurovac D: The magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in Kenya. Malar J. 2012, 11: 37-10.1186/1475-2875-11-37.PubMedCentralCrossRefPubMed Sudoi RK, Githinji S, Nyandigisi A, Muturi A, Snow RW, Zurovac D: The magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in Kenya. Malar J. 2012, 11: 37-10.1186/1475-2875-11-37.PubMedCentralCrossRefPubMed
24.
go back to reference Senn N, Rarau P, Manong D, Salib M, Siba P, Robinson LJ, Reeder J, Rogerson S, Mueller I, Genton B: Rapid diagnostic test-based management of malaria: an effectiveness study in Papua New Guinean infants with Plasmodium falciparum and Plasmodium vivax malaria. Clin Infect Dis. 2012, 54: 644-651. 10.1093/cid/cir901.CrossRefPubMed Senn N, Rarau P, Manong D, Salib M, Siba P, Robinson LJ, Reeder J, Rogerson S, Mueller I, Genton B: Rapid diagnostic test-based management of malaria: an effectiveness study in Papua New Guinean infants with Plasmodium falciparum and Plasmodium vivax malaria. Clin Infect Dis. 2012, 54: 644-651. 10.1093/cid/cir901.CrossRefPubMed
25.
go back to reference World Health Organisation: Global plan for artemisinin resistance containment (GPARC). 2011, Geneva: World Health Organisation World Health Organisation: Global plan for artemisinin resistance containment (GPARC). 2011, Geneva: World Health Organisation
26.
go back to reference Batwala V, Magnussen P, Hansen KS, Nuwaha F: Cost-effectiveness of malaria microscopy and rapid diagnostic tests versus presumptive diagnosis: implications for malaria control in Uganda. Malar J. 2011, 10: 372-10.1186/1475-2875-10-372.PubMedCentralCrossRefPubMed Batwala V, Magnussen P, Hansen KS, Nuwaha F: Cost-effectiveness of malaria microscopy and rapid diagnostic tests versus presumptive diagnosis: implications for malaria control in Uganda. Malar J. 2011, 10: 372-10.1186/1475-2875-10-372.PubMedCentralCrossRefPubMed
27.
go back to reference Amexo M, Tolhurst R, Barnish G, Bates I: Malaria misdiagnosis: effects on the poor and vulnerable. Lancet. 2004, 364: 1896-1898. 10.1016/S0140-6736(04)17446-1.CrossRefPubMed Amexo M, Tolhurst R, Barnish G, Bates I: Malaria misdiagnosis: effects on the poor and vulnerable. Lancet. 2004, 364: 1896-1898. 10.1016/S0140-6736(04)17446-1.CrossRefPubMed
28.
go back to reference Rowe AK, de Savigny D, Lanata CF, Victora CG: How can we achieve and maintain high-quality performance of health workers in low-resource settings?. Lancet. 2005, 366: 1026-1035. 10.1016/S0140-6736(05)67028-6.CrossRefPubMed Rowe AK, de Savigny D, Lanata CF, Victora CG: How can we achieve and maintain high-quality performance of health workers in low-resource settings?. Lancet. 2005, 366: 1026-1035. 10.1016/S0140-6736(05)67028-6.CrossRefPubMed
29.
go back to reference Bande G, Hetzel MW, Iga J, Barnadas C, Mueller I, Siba P, Horwood PF: An investigation into febrile illnesses of unknown aetiology in Wipim, Papua New Guinea. P N G Med J. In press Bande G, Hetzel MW, Iga J, Barnadas C, Mueller I, Siba P, Horwood PF: An investigation into febrile illnesses of unknown aetiology in Wipim, Papua New Guinea. P N G Med J. In press
30.
go back to reference Senn N, Luang-Suarkia D, Manong D, Siba PM, McBride WJ: Contribution of dengue fever to the burden of acute febrile illnesses in Papua New Guinea: an age-specific prospective study. Am J Trop Med Hyg. 2011, 85: 132-137. 10.4269/ajtmh.2011.10-0482.PubMedCentralCrossRefPubMed Senn N, Luang-Suarkia D, Manong D, Siba PM, McBride WJ: Contribution of dengue fever to the burden of acute febrile illnesses in Papua New Guinea: an age-specific prospective study. Am J Trop Med Hyg. 2011, 85: 132-137. 10.4269/ajtmh.2011.10-0482.PubMedCentralCrossRefPubMed
31.
go back to reference Horwood P, Dagina R, Bande G, Reimer L, Koimbu G, Katusele M, Jimmy S, Ropa B, Siba P, Pavlin B: Outbreak of chikungunya virus infection, Vanimo, Papua New Guinea. Emerg Infect Dis. 2013, 19: 1535-1538. 10.3201/eid1909.130130.PubMedCentralCrossRefPubMed Horwood P, Dagina R, Bande G, Reimer L, Koimbu G, Katusele M, Jimmy S, Ropa B, Siba P, Pavlin B: Outbreak of chikungunya virus infection, Vanimo, Papua New Guinea. Emerg Infect Dis. 2013, 19: 1535-1538. 10.3201/eid1909.130130.PubMedCentralCrossRefPubMed
Metadata
Title
Malaria case management in Papua New Guinea following the introduction of a revised treatment protocol
Publication date
01-12-2013
Published in
Malaria Journal / Issue 1/2013
Electronic ISSN: 1475-2875
DOI
https://doi.org/10.1186/1475-2875-12-433

Other articles of this Issue 1/2013

Malaria Journal 1/2013 Go to the issue