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Open Access 01-12-2012 | Case report

Artemether–lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania

Authors: Anna Färnert, Johan Ursing, Thomas Tolfvenstam, Josea Rono, Lillemor Karlsson, Elda Sparrelid, Niklas Lindegårdh

Published in: Malaria Journal | Issue 1/2012

Abstract

Artemether-lumefantrine is currently first-line therapy of Plasmodium falciparum malaria in many countries. This report describes a treatment failure despite adequate drug concentrations in a traveller returning from sub-Saharan Africa. Genotyping confirmed recrudescence and suggested reduced sensitivity. Potential sub-optimal effect of artemether-lumefantrine highlights the need to follow non-immune individuals the weeks after treatment.

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Title: Artemether–lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania
Authors: Anna Färnert
Johan Ursing
Thomas Tolfvenstam
Josea Rono
Lillemor Karlsson
Elda Sparrelid
Niklas Lindegårdh
Publication date: 01-12-2012
Publisher: BioMed Central
Published in: Malaria Journal / Issue 1/2012
Electronic ISSN: 1475-2875
DOI: https://doi.org/10.1186/1475-2875-11-176

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