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Published in: BMC Surgery 1/2014

Open Access 01-12-2014 | Case report

Successful surgical approach for a patient with encapsulating peritoneal sclerosis after hyperthermic intraperitoneal chemotherapy: a case report and literature review

Authors: Katsushi Takebayashi, Hiromichi Sonoda, Tomoharu Shimizu, Hiroyuki Ohta, Mitsuaki Ishida, Eiji Mekata, Yoshihiro Endo, Tohru Tani, Masaji Tani

Published in: BMC Surgery | Issue 1/2014

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Abstract

Background

Encapsulating peritoneal sclerosis (EPS) is a rare surgical complication that can occur after intraperitoneal treatment. It is also a serious and potentially fatal complication of continuous ambulatory peritoneal dialysis. The present report describes a case of surgically treated EPS that probably occurred as a complication of hyperthermic intraperitonal chemotherapy (HIPEC).

Case presentation

A 39-year-old man required sigmoidectomy for serosal invasive advanced sigmoid colon cancer. HIPEC with oxaliplatin, 5-fluorouracil and mitomycin C were given as adjuvant therapy. Subsequently, intestinal obstruction developed at 15 months postoperatively, and the patient was hospitalized. Abdominal computed tomography showed a dilated small intestine enveloped by a thickened membrane. We found no evidence of peritoneal recurrence, but exploratory surgery revealed EPS, probably caused by HIPEC. We peeled the capsule off of the intestine. The patient’s postoperative course was uneventful, and sufficient nutritional intake after surgery was noted. Seven months after surgery, he is well with no recurrence.

Conclusion

The surgical treatment via peritonectomy and enterolysis for postoperative EPS appears safe and effective. A diagnosis of EPS should be considered when intestinal obstruction does not show improvement with conservative treatment in patients who have undergone HIPEC, provided the possibility of peritoneal cancer recurrence is excluded.
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Metadata
Title
Successful surgical approach for a patient with encapsulating peritoneal sclerosis after hyperthermic intraperitoneal chemotherapy: a case report and literature review
Authors
Katsushi Takebayashi
Hiromichi Sonoda
Tomoharu Shimizu
Hiroyuki Ohta
Mitsuaki Ishida
Eiji Mekata
Yoshihiro Endo
Tohru Tani
Masaji Tani
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Surgery / Issue 1/2014
Electronic ISSN: 1471-2482
DOI
https://doi.org/10.1186/1471-2482-14-57

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